Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/24158
Title: All-diamond functional surface micro-electrode arrays for brain-slice neural analysis
Authors: VAHIDPOUR, Farnoosh 
Curley, Lowry
Biro, Istvan
MCDONALD, Matthew 
CROUX, Dieter 
POBEDINSKAS, Paulius 
HAENEN, Ken 
Giugliano, Michele
Zivcova, Zuzana Vlckova
Kavan, Ladislav
NESLADEK, Milos 
Issue Date: 2017
Publisher: WILEY-V C H VERLAG GMBH
Source: PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 214(2) (Art N° 1532347)
Abstract: Diamond-based microelectrode arrays were fabricated by using nanocrystalline diamond as an insulating layer and conductive boron-doped in order to used them for analysis of brain cortical slices. MEA surface is solely composed of diamond, exposed to the cells. The impedance measurements showed negligible cross-talk between neighbouring diamond microelectrodes. Local field potentials related to neural signals were then successfully recorded from pharmacologically disinhibited rat cortical tissue slices, mechanically coupled on the surface of the MEA. The background signal level of the diamond MEAs was found to be lower than commercial Pt-based MEAs, under identical measurement conditions.
Notes: [Vahidpour, Farnoosh; McDonald, Matthew; Pobedinskas, Paulius; Haenen, Ken; Nesladek, Milos] Hasselt Univ, Inst Mat Res IMO, Hasselt, Belgium. [Curley, Lowry; Biro, Istvan; Giugliano, Michele] Univ Antwerp, Dept Biomed Sci, Theoret Neurobiol & Neuroengn Lab, Antwerp, Belgium. [McDonald, Matthew; Haenen, Ken; Giugliano, Michele; Nesladek, Milos] IMEC VZW, IMOMEC, Leuven, Belgium. [Giugliano, Michele] Swiss Fed Inst Technol Lausanne, Brain Mind Inst, Lausanne, Switzerland. [Giugliano, Michele] Univ Sheffield, Dept Comp Sci, Sheffield, S Yorkshire, England. [Zivcova, Zuzana Vlckova; Kavan, Ladislav] J Heyrovsky Inst Phys Chem AS CR, Vvi, Dept Elect Mat, Prague, Czech Republic.
Keywords: impedance spectroscopy; microelectrode arrays; surface termination;impedance spectroscopy; microelectrode arrays; surface termination
Document URI: http://hdl.handle.net/1942/24158
ISSN: 1862-6300
e-ISSN: 1862-6319
DOI: 10.1002/pssa.201532347
ISI #: 000395007800027
Rights: © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Category: A1
Type: Journal Contribution
Validations: ecoom 2018
Appears in Collections:Research publications

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