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http://hdl.handle.net/1942/24321
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DC Field | Value | Language |
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dc.contributor.author | PETERS, Martijn | - |
dc.contributor.author | Scharmga, A. | - |
dc.contributor.author | van Tubergen, A. | - |
dc.contributor.author | Arts, J. | - |
dc.contributor.author | Loeffen, D. | - |
dc.contributor.author | Weijers, R. | - |
dc.contributor.author | van Rietbergen, B. | - |
dc.contributor.author | GEUSENS, Piet | - |
dc.contributor.author | VAN DEN BERGH, Joop | - |
dc.date.accessioned | 2017-08-31T08:01:18Z | - |
dc.date.available | 2017-08-31T08:01:18Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | CALCIFIED TISSUE INTERNATIONAL, 101(2), p. 132-140 | - |
dc.identifier.issn | 0171-967X | - |
dc.identifier.uri | http://hdl.handle.net/1942/24321 | - |
dc.description.abstract | We developed a semi-automated algorithm for the detection of cortical interruptions in finger joints using high-resolution peripheral quantitative computed tomography (HR-pQCT). Here, we tested its reliability compared to microCT (A mu CT) as gold standard. Nineteen joints of 10 female anatomic index fingers were imaged by HR-pQCT and A mu CT (82 and 18 A mu m isotropic voxel sizes, respectively). The algorithm was applied for detection of cortical interruptions of different minimum diameters (range > 0.16 to > 0.50 mm). Reliability was tested at the joint level with intra-class correlation coefficient (ICC) for the number of interruptions and interruption surface, and at the level of a single interruption for matching between HR-pQCT and A mu CT with a fixed interruption diameter (> 0.10 mm) on A mu CT. The positive predictive value (PPV0.10mm) and sensitivity(0.10mm) were evaluated. The mean number of interruptions per joint depended on the diameter cut-off and ranged from 3.4 to 53.5 on HR-pQCT and from 1.8 to 45.1 on A mu CT for interruptions > 0.50 to > 0.16 mm, respectively. Reliability at the joint level was almost perfect (ICC >= 0.81) for both the number and surface of interruptions > 0.16 and > 0.33 mm. As expected, the PPV0.10mm increased with increasing interruption diameter from 84.9 to 100%, for interruptions > 0.16 and > 0.50 mm, respectively. However, the sensitivity(0.10mm) decreased with increasing interruption diameter from 62.4 to 4.7%. This semi-automated algorithm for HR-pQCT in finger joints performed best for the detection of cortical interruptions with a minimum diameter of > 0.16 or > 0.33 mm, showing almost perfect reliability at the joint level and interruptions matched with those on A mu CT. | - |
dc.description.sponsorship | The study is supported by unrestricted grants from the Weijerhorst foundation and Pfizer. | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.rights | © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. | - |
dc.subject.other | Cortical interruptions; High resolution peripheral quantitative computed tomography; Micro computed tomography; Finger joints; Rheumatoid arthritis | - |
dc.subject.other | cortical interruptions; high resolution peripheral quantitative computed tomography; micro computed tomography; finger joints; rheumatoid arthritis | - |
dc.title | The Reliability of a Semi-automated Algorithm for Detection of Cortical Interruptions in Finger Joints on High Resolution CT Compared to MicroCT | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 140 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 132 | - |
dc.identifier.volume | 101 | - |
local.format.pages | 9 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Peters, M.; Scharmga, A.; van Tubergen, A.; Geusens, P.; van den Bergh, J. P.] Maastricht Univ, Div Rheumatol, Dept Internal Med, Med Ctr, POB 5800, NL-6202 AZ Maastricht, Netherlands. [Peters, M.; Scharmga, A.; van Tubergen, A.; Geusens, P.] Res Sch CAPHRI, Sch Publ Hlth & Primary Care, Maastricht, Netherlands. [Peters, M.; Scharmga, A.; van den Bergh, J. P.] Maastricht Univ, NUTRIM Sch Nutr & Translat Res Metab, Maastricht, Netherlands. [Arts, J.; van Rietbergen, B.] Maastricht Univ, Dept Orthopaed Surg, Med Ctr, Maastricht, Netherlands. [Arts, J.; van Rietbergen, B.] Eindhoven Univ Technol, Fac Biomed Engn, Eindhoven, Netherlands. [Loeffen, D.; Weijers, R.] Maastricht Univ, Dept Radiol, Med Ctr, Maastricht, Netherlands. [Geusens, P.; van den Bergh, J. P.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. [van den Bergh, J. P.] VieCuri Med Ctr, Dept Internal Med, Venlo, Netherlands. | - |
local.publisher.place | NEW YORK | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.class | dsPublValOverrule/author_version_not_expected | - |
dc.identifier.doi | 10.1007/s00223-017-0264-5 | - |
dc.identifier.isi | 000404907500002 | - |
item.accessRights | Open Access | - |
item.fullcitation | PETERS, Martijn; Scharmga, A.; van Tubergen, A.; Arts, J.; Loeffen, D.; Weijers, R.; van Rietbergen, B.; GEUSENS, Piet & VAN DEN BERGH, Joop (2017) The Reliability of a Semi-automated Algorithm for Detection of Cortical Interruptions in Finger Joints on High Resolution CT Compared to MicroCT. In: CALCIFIED TISSUE INTERNATIONAL, 101(2), p. 132-140. | - |
item.contributor | PETERS, Martijn | - |
item.contributor | Scharmga, A. | - |
item.contributor | van Tubergen, A. | - |
item.contributor | Arts, J. | - |
item.contributor | Loeffen, D. | - |
item.contributor | Weijers, R. | - |
item.contributor | van Rietbergen, B. | - |
item.contributor | GEUSENS, Piet | - |
item.contributor | VAN DEN BERGH, Joop | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2018 | - |
crisitem.journal.issn | 0171-967X | - |
crisitem.journal.eissn | 1432-0827 | - |
Appears in Collections: | Research publications |
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