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http://hdl.handle.net/1942/24330
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DC Field | Value | Language |
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dc.contributor.author | Van Der Berg, Julianne D. | - |
dc.contributor.author | Van Der Velde, Jeroenh. P. M. | - |
dc.contributor.author | De Waard, Ellis A. C. | - |
dc.contributor.author | Bosma, Hans | - |
dc.contributor.author | Savelberg, Hans H. C. M. | - |
dc.contributor.author | Schaper, Nicolaas C. | - |
dc.contributor.author | VAN DEN BERGH, Joop | - |
dc.contributor.author | GEUSENS, Piet | - |
dc.contributor.author | Schram, Miranda T. | - |
dc.contributor.author | Sep, Simone J. S. | - |
dc.contributor.author | VAN DER KALLEN, Carla | - |
dc.contributor.author | Henry, Ronaldm. A. | - |
dc.contributor.author | Dagnelie, Pieter C. | - |
dc.contributor.author | Eussen, Simone J. P. M. | - |
dc.contributor.author | Van Dongen, Martien C. J. M. | - |
dc.contributor.author | Kohler, Sebastian | - |
dc.contributor.author | Kroon, Abraham A. | - |
dc.contributor.author | Stehouwer, Coen D. A. | - |
dc.contributor.author | Koster, Annemarie | - |
dc.date.accessioned | 2017-08-31T08:44:34Z | - |
dc.date.available | 2017-08-31T08:44:34Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 49(7), p. 1347-1354 | - |
dc.identifier.issn | 0195-9131 | - |
dc.identifier.uri | http://hdl.handle.net/1942/24330 | - |
dc.description.abstract | Introduction: Sedentary time has been associated with detrimental health effects, so in some countries, guidelines to reduce sedentary time have been developed. As reducing sedentary time inevitably results in more nonsedentary time, effects of this reduction may depend on the activity with which it is replaced. Purpose: This study aimed to examine associations of theoretical reallocations of sedentary time to standing or stepping with cardiometabolic outcomes and type 2 diabetes. Methods: We included 2213 participants (51% men, mean +/- SD age = 60.0 +/- 8.1 yr) of the Maastricht Study who were asked to wear an accelerometer 24 h.d(-1) for a week. We calculated daily sedentary, standing, and stepping time. An isotemporal substitution modeling approach was applied to examine effects on waist circumference; body mass index; cholesterol, triacylglycerol, glucose, and insulin levels; metabolic syndrome; and type 2 diabetes. Results: Replacement of sedentary time (30 min.d(-1)) with stepping was associated with lower odds for metabolic syndrome (odds ratio [OR] = 0.72, 95% confidence interval [CI] = 0.66-0.78) and type 2 diabetes (OR = 0.79, 95% CI = 0.72-0.87), more favorable waist circumference (B = -1.42, 95% CI = -1.78 to -1.06), and body mass index (B = -0.48, 95% CI = -0.62 to -0.35) and improved cholesterol, triacylglycerol, glucose, and insulin levels. Replacing sedentary time with standing was associated with lower odds for metabolic syndrome and type 2 diabetes and favorable outcomes in waist circumference, cholesterol, triacylglycerol, and insulin levels. Conclusion: Theoretical replacements of sedentary time with nonsedentary time (both standing and stepping) were associated with lower odds for metabolic syndrome, type 2 diabetes, and beneficial metabolic outcomes. These results could be important for the general population, including those who cannot meet physical activity guidelines. Consideration should be given to developing recommendations for daily reallocating sedentary time. | - |
dc.description.sponsorship | This study was supported by the European Regional Development Fund via OP-Zuid, the Province of Limburg, the Dutch Ministry of Economic Affairs (grant no. 31O.041), Stichting De Weijerhorst (Maastricht, the Netherlands), the Pearl String Initiative Diabetes (Amsterdam, the Netherlands), the Cardiovascular Center (CVC, Maastricht, the Netherlands), CARIM School for Cardiovascular Diseases (Maastricht, the Netherlands), CAPHRI School for Public Health and Primary Care (Maastricht, the Netherlands), NUTRIM School for Nutrition and Translational Research in Metabolism (Maastricht, the Netherlands), Stichting Annadal (Maastricht, the Netherlands), and Health Foundation Limburg (Maastricht, the Netherlands) and by unrestricted grants from Janssen-Cilag B.V. (Tilburg, the Netherlands), Novo Nordisk Farma B.V. (Alphen aan den Rijn, the Netherlands), and Sanofi-Aventis Netherlands B.V. (Gouda, the Netherlands). A Koster has received funding from the European Union Seventh Framework Programme (FP7-PEOPLE-2011-CIG) under grant agreement PCIG09-GA-2011-293621. | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.rights | Copyright © 2017 American College of Sports Medicine | - |
dc.subject.other | SEDENTARY LIFESTYLE; DIABETES MELLITUS TYPE 2; METABOLIC SYNDROME; ACCELEROMETRY; ISOTEMPORAL SUBSTITUTION MODELING | - |
dc.subject.other | accelerometer; doubly-labeled water; physical activity questionnaire; cardiometabolic risk; endocrine health; exercise | - |
dc.title | Replacement Effects of Sedentary Time on Metabolic Outcomes: The Maastricht Study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1354 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1347 | - |
dc.identifier.volume | 49 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Van Der Berg, Julianne D.; Bosma, Hans; Koster, Annemarie] Maastricht Univ, Dept Social Med, Maastricht, Netherlands. [Van Der Berg, Julianne D.; Bosma, Hans; Schaper, Nicolaas C.; Geusens, Piet P. M. M.; Dagnelie, Pieter C.; Eussen, Simone J. P. M.; Van Dongen, Martien C. J. M.; Koster, Annemarie] Maastricht Univ, CAPHRI Care & Publ Hlth Res Inst, Maastricht, Netherlands. [Van Der Berg, Julianne D.] Radboud Univ Nijmegen, Radboud Inst Hlth Sci, Med Ctr, Nijmegen, Netherlands. [Van Der Velde, Jeroenh. P. M.; Savelberg, Hans H. C. M.] Maastricht Univ, Dept Human Movement Sci, Maastricht, Netherlands. [Van Der Velde, Jeroenh. P. M.; De Waard, Ellis A. C.; Savelberg, Hans H. C. M.; Van Den Bergh, Joop P. W.] Maastricht Univ, NUTRIM Sch Nutr & Translat Res Metab, Maastricht, Netherlands. [Van Der Velde, Jeroenh. P. M.; De Waard, Ellis A. C.; Schaper, Nicolaas C.; Van Den Bergh, Joop P. W.; Geusens, Piet P. M. M.; Schram, Miranda T.; Sep, Simone J. S.; Van Der Kallen, Carla J. H.; Henry, Ronaldm. A.; Kroon, Abraham A.; Stehouwer, Coen D. A.] Maastricht Univ, Dept Internal Med, Med Ctr, Maastricht, Netherlands. [Schaper, Nicolaas C.; Schram, Miranda T.; Sep, Simone J. S.; Van Der Kallen, Carla J. H.; Henry, Ronaldm. A.; Dagnelie, Pieter C.; Eussen, Simone J. P. M.; Kroon, Abraham A.; Stehouwer, Coen D. A.] Maastricht Univ, CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. [Van Den Bergh, Joop P. W.; Geusens, Piet P. M. M.] Univ Hasselt, Biomed Res Inst, Diepenbeek, Belgium. [Van Den Bergh, Joop P. W.] VieCuri Med Ctr, Dept Internal Med, Venlo, Netherlands. [Dagnelie, Pieter C.; Eussen, Simone J. P. M.; Van Dongen, Martien C. J. M.] Maastricht Univ, Dept Epidemiol, Maastricht, Netherlands. [Kohler, Sebastian] Maastricht Univ, Dept Psychiat & Neuropsychol, Maastricht, Netherlands. [Kohler, Sebastian] Maastricht Univ, MHeNS Sch Mental Hlth & Neurosci, Maastricht, Netherlands. | - |
local.publisher.place | PHILADELPHIA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1249/MSS.0000000000001248 | - |
dc.identifier.isi | 000403552100008 | - |
item.fulltext | With Fulltext | - |
item.contributor | Van Der Berg, Julianne D. | - |
item.contributor | Van Der Velde, Jeroenh. P. M. | - |
item.contributor | De Waard, Ellis A. C. | - |
item.contributor | Bosma, Hans | - |
item.contributor | Savelberg, Hans H. C. M. | - |
item.contributor | Schaper, Nicolaas C. | - |
item.contributor | VAN DEN BERGH, Joop | - |
item.contributor | GEUSENS, Piet | - |
item.contributor | Schram, Miranda T. | - |
item.contributor | Sep, Simone J. S. | - |
item.contributor | VAN DER KALLEN, Carla | - |
item.contributor | Henry, Ronaldm. A. | - |
item.contributor | Dagnelie, Pieter C. | - |
item.contributor | Eussen, Simone J. P. M. | - |
item.contributor | Van Dongen, Martien C. J. M. | - |
item.contributor | Kohler, Sebastian | - |
item.contributor | Kroon, Abraham A. | - |
item.contributor | Stehouwer, Coen D. A. | - |
item.contributor | Koster, Annemarie | - |
item.accessRights | Open Access | - |
item.fullcitation | Van Der Berg, Julianne D.; Van Der Velde, Jeroenh. P. M.; De Waard, Ellis A. C.; Bosma, Hans; Savelberg, Hans H. C. M.; Schaper, Nicolaas C.; VAN DEN BERGH, Joop; GEUSENS, Piet; Schram, Miranda T.; Sep, Simone J. S.; VAN DER KALLEN, Carla; Henry, Ronaldm. A.; Dagnelie, Pieter C.; Eussen, Simone J. P. M.; Van Dongen, Martien C. J. M.; Kohler, Sebastian; Kroon, Abraham A.; Stehouwer, Coen D. A. & Koster, Annemarie (2017) Replacement Effects of Sedentary Time on Metabolic Outcomes: The Maastricht Study. In: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 49(7), p. 1347-1354. | - |
item.validation | ecoom 2018 | - |
crisitem.journal.issn | 0195-9131 | - |
crisitem.journal.eissn | 1530-0315 | - |
Appears in Collections: | Research publications |
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aaa.pdf | Peer-reviewed author version | 2 MB | Adobe PDF | View/Open |
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