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http://hdl.handle.net/1942/24377
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DC Field | Value | Language |
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dc.contributor.author | Smit, G. Suzanne A. | - |
dc.contributor.author | PADALKO, Elizaveta | - |
dc.contributor.author | Van Acker, Jos | - |
dc.contributor.author | HENS, Niel | - |
dc.contributor.author | Dorny, Pierre | - |
dc.contributor.author | Speybroeck, Niko | - |
dc.contributor.author | Devleesschauwer, Brecht | - |
dc.date.accessioned | 2017-09-06T11:43:00Z | - |
dc.date.available | 2017-09-06T11:43:00Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | CLINICAL INFECTIOUS DISEASES, 65(4), p. 661-668 | - |
dc.identifier.issn | 1058-4838 | - |
dc.identifier.uri | http://hdl.handle.net/1942/24377 | - |
dc.description.abstract | Congenital toxoplasmosis (CT) and cytomegalovirus infection (cCMV) may cause significant morbidity and even fetal or neonatal mortality. We aimed to quantify the disease burden of CT and cCMV in Belgium in terms of disability-adjusted life years (DALYs) and identify data gaps. The public health impact of CT and cCMV in Belgium in 2013 was 188 (95% uncertainty interval [UI], 43-419) and 1976 (95% UI, 757-4067) DALYs, respectively. The major data gaps identified were representative Belgian studies; information on important sequelae, intrauterine mortality, and termination of pregnancy; and late onset sequelae. A scenario analysis showed important increases in years of life lost when the burden due to fetal losses was included and decreases in DALYs when comprehensive CT prevention measures were conducted. Addressing the key data gaps identified may allow generation of the data needed to break the vicious circle of underrecognition. | - |
dc.description.sponsorship | This work was supported by the Research Foundation-Flanders (FWO Aspirant), Brussels, Belgium. N. H. gratefully acknowledges support from the University of Antwerp Scientific Chair in Evidence-Based Vaccinology, financed in 2009-2016 by a gift from Pfizer and in 2016 from GSK. | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS INC | - |
dc.rights | © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. | - |
dc.subject.other | congenital infections; data gaps; burden of disease; DALY | - |
dc.subject.other | congenital infections; data gaps; burden of disease; DALY | - |
dc.title | Public Health Impact of Congenital Toxoplasmosis and Cytomegalovirus Infection in Belgium, 2013: A Systematic Review and Data Synthesis | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 668 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 661 | - |
dc.identifier.volume | 65 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Smit, G. Suzanne A.; Dorny, Pierre] Univ Ghent, Fac Vet Med, Dept Virol Parasitol & Immunol, Salisburylaan 133, B-9820 Merelbeke, Belgium. [Smit, G. Suzanne A.; Dorny, Pierre] Inst Trop Med, Dept Biomed Sci, Antwerp, Belgium. [Smit, G. Suzanne A.; Speybroeck, Niko] Catholic Univ Louvain, Inst Hlth & Soc, Brussels, Belgium. [Padalko, Elizaveta] Ghent Univ Hosp, Dept Clin Biol Microbiol & Immunol, Diepenbeek, Belgium. [Padalko, Elizaveta] Hasselt Univ, Sch Life Sci, Diepenbeek, Belgium. [Van Acker, Jos] AZ Sint Lucas, Lab Clin Microbiol, Ghent, Belgium. [Hens, Niel] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Diepenbeek, Belgium. [Hens, Niel] Vaccine & Infect Dis Inst, Ctr Hlth Econ Res & Modelling Infect Dis, Antwerp, Belgium. [Hens, Niel] Univ Antwerp, Epidemiol & Social Med, Antwerp, Belgium. [Devleesschauwer, Brecht] Sci Inst Publ Hlth, Dept Publ Hlth & Surveillance, Brussels, Belgium. | - |
local.publisher.place | CARY | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1093/cid/cix344 | - |
dc.identifier.isi | 000406670800019 | - |
item.validation | ecoom 2018 | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.fullcitation | Smit, G. Suzanne A.; PADALKO, Elizaveta; Van Acker, Jos; HENS, Niel; Dorny, Pierre; Speybroeck, Niko & Devleesschauwer, Brecht (2017) Public Health Impact of Congenital Toxoplasmosis and Cytomegalovirus Infection in Belgium, 2013: A Systematic Review and Data Synthesis. In: CLINICAL INFECTIOUS DISEASES, 65(4), p. 661-668. | - |
item.contributor | Smit, G. Suzanne A. | - |
item.contributor | PADALKO, Elizaveta | - |
item.contributor | Van Acker, Jos | - |
item.contributor | HENS, Niel | - |
item.contributor | Dorny, Pierre | - |
item.contributor | Speybroeck, Niko | - |
item.contributor | Devleesschauwer, Brecht | - |
crisitem.journal.issn | 1058-4838 | - |
crisitem.journal.eissn | 1537-6591 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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smit2017.pdf Restricted Access | Published version | 330.76 kB | Adobe PDF | View/Open Request a copy |
SRB_manuscript_AuthorsVersion.pdf | Peer-reviewed author version | 5.02 MB | Adobe PDF | View/Open |
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