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http://hdl.handle.net/1942/24988
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DC Field | Value | Language |
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dc.contributor.author | Aminipour, Zahra | - |
dc.contributor.author | KHORSHID, Mehran | - |
dc.contributor.author | Bayoumi, Mariam | - |
dc.contributor.author | LOSADA-PEREZ, Patricia | - |
dc.contributor.author | THOELEN, Ronald | - |
dc.contributor.author | Bonakdar, Shahin | - |
dc.contributor.author | Keshvari, Hamid | - |
dc.contributor.author | Maglia, Giovanni | - |
dc.contributor.author | WAGNER, Patrick | - |
dc.contributor.author | Van der Bruggen, Bart | - |
dc.date.accessioned | 2017-10-10T13:43:00Z | - |
dc.date.available | 2017-10-10T13:43:00Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 214(9), p. 1-8 (Art N° 1700104) | - |
dc.identifier.issn | 1862-6300 | - |
dc.identifier.uri | http://hdl.handle.net/1942/24988 | - |
dc.description.abstract | Black lipid membranes (BLMs) are planar lipid bilayers that can be formed in porous supports such as filters. A BLM as a biomimetic membrane has important applications in, for instance, biosensing and drug-permeability assays. In the present study, BLMs were formed in the pores of three different filters to investigate their ability to support the formation of a high-quality lipid bilayer. Poly (vinylidene fluoride) (PVDF), poly(acrylonitrile) (PAN), and polypropylene/polyethylene (PP/PE) filters were utilized as filter supports, and the bilayer formation was monitored in situ by capacitance measurements. The maximum capacitance was obtained for PVDF (5.34Fcm(-2)) versus PP/PE and PAN (2.95 and 0.91Fcm(-2), respectively). Additionally, BLM leakage current measurements by wave deviation provided consistent results. Thickness and compactness of the bilayers were evaluated using pore forming protein (ClyA) insertion. The results show that PVDF with the highest porosity level was the most suitable support for BLM formation. The optimal thickness for the BLM in PVDF was 3-5nm, where the most efficient protein insertion took place, in comparison with other filters. | - |
dc.description.sponsorship | This study was funded by the Research Foundation Flanders (FWO), project G.0B62.13N. Technical support on flow cell design by Dr. P. Cornelis, Drs. G. Wackers, W. Neefs (lab technician), proofreading by Dr. D. Yongabi, assistance on SEM measurements by Dr. V. Zharinov, and Prof. J. Van de Vondel (all from Department of Physics and Astronomy, KULeuven) are gratefully appreciated. We would also like to thank Dr. H. Farrokhzad, lab technicians, M. Vanroelen, and H. Tollet (Department of Chemical Engineering, KULeuven), and Dr. E. Darestani Farahani (Department of Medicine, KULeuven) cordially for many stimulating discussions and data analysis. | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.rights | (C) 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim | - |
dc.subject.other | bilayers; biosensors; black lipid membranes; filters; porous materials; protein nanopores | - |
dc.subject.other | bilayers; biosensors; black lipid membranes; filters; porous materials; protein nanopores | - |
dc.title | Formation and electrical characterization of black lipid membranes in porous filter materials | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 8 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 1 | - |
dc.identifier.volume | 214 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Aminipour, Zahra; Keshvari, Hamid] Amirkabir Univ Technol, Fac Biomed Engn, 424 Hafez Ave, Tehran, Iran. [Aminipour, Zahra; Khorshid, Mehran; Van der Bruggen, Bart] KULeuven, Dept Chem Engn, Proc Engn Sustainable Syst, Celestijnenlaan 200 F, B-3001 Leuven, Belgium. [Wagner, Patrick] KULeuven, Dept Phys & Astron, Soft Matter Phys & Biophys Sect, Celestijnenlaan 200 D, B-3001 Leuven, Belgium. [Khorshid, Mehran; Losada-Perez, Patricia; Thoelen, Ronald] Hasselt Univ, Inst Mat Res, Wetenschapspk 1, B-3590 Diepenbeek, Belgium. [Bayoumi, Mariam; Maglia, Giovanni] KULeuven, Dept Chem, Celestijnenlaan 200 G, B-3001 Leuven, Belgium. [Bonakdar, Shahin] Pasteur Inst Iran, Natl Cell Bank, 12th Farwardin Ave 69, Tehran, Iran. [Maglia, Giovanni] Univ Groningen, Groningen Biomol Sci & Biotechnol Inst, Nijenborgh 7, NL-9747 AG Groningen, Netherlands. [Van der Bruggen, Bart] Tshwane Univ Technol, Fac Engn & Built Environm, Private Bag X680, ZA-0001 Pretoria, South Africa. | - |
local.publisher.place | WEINHEIM | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 1700104 | - |
dc.identifier.doi | 10.1002/pssa.201700104 | - |
dc.identifier.isi | 000409906900031 | - |
item.contributor | Aminipour, Zahra | - |
item.contributor | KHORSHID, Mehran | - |
item.contributor | Bayoumi, Mariam | - |
item.contributor | LOSADA-PEREZ, Patricia | - |
item.contributor | THOELEN, Ronald | - |
item.contributor | Bonakdar, Shahin | - |
item.contributor | Keshvari, Hamid | - |
item.contributor | Maglia, Giovanni | - |
item.contributor | WAGNER, Patrick | - |
item.contributor | Van der Bruggen, Bart | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2018 | - |
item.fullcitation | Aminipour, Zahra; KHORSHID, Mehran; Bayoumi, Mariam; LOSADA-PEREZ, Patricia; THOELEN, Ronald; Bonakdar, Shahin; Keshvari, Hamid; Maglia, Giovanni; WAGNER, Patrick & Van der Bruggen, Bart (2017) Formation and electrical characterization of black lipid membranes in porous filter materials. In: PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 214(9), p. 1-8 (Art N° 1700104). | - |
item.accessRights | Restricted Access | - |
crisitem.journal.issn | 1862-6300 | - |
crisitem.journal.eissn | 1862-6319 | - |
Appears in Collections: | Research publications |
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pssa201700104.pdf Restricted Access | Published version | 975.99 kB | Adobe PDF | View/Open Request a copy |
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