Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/25038
Title: Introducing SPAAC and SPIEDAC coupling chemistry into the VCAM-1 targeting nanobody for advanced medical biomaterials
Authors: HANSEN, Rebekka 
ADRIAENSENS, Peter 
GUEDENS, Wanda 
Issue Date: 2017
Source: Symposium 'Advanced Materials for Biomedical Applications' (AMBA 2017), Ghent, Belgium, 27-29/09/2017
Abstract: The goal of this project is to site-specifically functionalize nanobodies with a copper-free ‘click’ functionality, to allow an oriented and covalent coupling to a complementary functionalized surface. A methodology is proposed in which an unnatural amino acid is introduced in the protein structure, with applications towards biosensor chips and affinity-based chromatography.
Document URI: http://hdl.handle.net/1942/25038
Category: C2
Type: Conference Material
Appears in Collections:Research publications

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