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http://hdl.handle.net/1942/26122
Title: | Western lifestyle and immunopathology of multiple sclerosis. | Authors: | MATVEEVA-KOLM, Olga BOGIE, Jeroen HENDRIKS, Jerome Linker, Ralf A. Haghikia, Aiden KLEINEWIETFELD, Markus |
Issue Date: | 2018 | Source: | Annals of the New York Academy of Sciences, 1417(1), p. 71-86 | Abstract: | There is increasing evidence for a sudden and unprecedented rise in the incidence of multiple sclerosis (MS) in Westernized countries over the past decades, emphasizing the role of environmental factors. Among many candidates, rapid changes in dietary habits seem to play a role in the pathogenesis of MS. Here, we summarize and discuss the available evidence for the role of dietary nutrients, such as table salt, fatty acids, and flavonoids, in the development and pathogenesis of MS. We also discuss new and emerging risk factors accompanying Western lifestyle, such as shift work, sleep, and circadian disruption. | Keywords: | diet; environmental risk factors; FOXP3(+) T-reg cells; multiple sclerosis; Western lifestyle; T(H)17 cells | Document URI: | http://hdl.handle.net/1942/26122 | ISSN: | 0077-8923 | e-ISSN: | 1749-6632 | DOI: | 10.1111/nyas.13583 | ISI #: | 000431488700005 | Rights: | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2019 |
Appears in Collections: | Research publications |
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Matveeva_et_al-2018-Annals_of_the_New_York_Academy_of_Sciences.pdf | Published version | 419.67 kB | Adobe PDF | View/Open |
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