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http://hdl.handle.net/1942/26315
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DC Field | Value | Language |
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dc.contributor.author | Schoenfeld, Lisa-Maria | - |
dc.contributor.author | DOOLEY, Dearbhaile | - |
dc.contributor.author | Jahanshahi, Ali | - |
dc.contributor.author | Temel, Yasin | - |
dc.contributor.author | HENDRIX, Sven | - |
dc.date.accessioned | 2018-07-12T13:21:45Z | - |
dc.date.available | 2018-07-12T13:21:45Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 83, p. 298-312 | - |
dc.identifier.issn | 0149-7634 | - |
dc.identifier.uri | http://hdl.handle.net/1942/26315 | - |
dc.description.abstract | Damage to the motor cortex induced by stroke or traumatic brain injury (TBI) can result in chronic motor deficits. For the development and improvement of therapies, animal models which possess symptoms comparable to the clinical population are used. However, the use of experimental animals raises valid ethical and methodological concerns. To decrease discomfort by experimental procedures and to increase the quality of results, non-invasive and sensitive rodent motor tests are needed. A broad variety of rodent motor tests are available to determine deficits after stroke or TBI. The current review describes and evaluates motor tests that fall into three categories: Tests to evaluate fine motor skills and grip strength, tests for gait and inter-limb coordination and neurological deficit scores. In this review, we share our thoughts on standardized data presentation to increase data comparability between studies. We also critically evaluate current methods and provide recommendations for choosing the best behavioral test for a new research line. | - |
dc.description.sponsorship | This work was supported in part by a grant from Hasselt University (BOF11603BOFMO) to SH and a grant from the Hersenstichting Nederland to YT. | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.rights | © 2017 Elsevier Ltd. All rights reserved. | - |
dc.subject.other | Motor tests; Rodents; Stroke; TBI | - |
dc.subject.other | motor tests; rodents; stroke; TBI | - |
dc.title | Evaluating rodent motor functions: Which tests to choose? | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 312 | - |
dc.identifier.spage | 298 | - |
dc.identifier.volume | 83 | - |
local.format.pages | 15 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Schoenfeld, Lisa-Maria] Heinrich Heine Univ Disseldof, Comparat Psychol, Inst Expt Psychol, Dusseldorf, Germany. [Dooley, Dearbhaile] Univ Coll Dublin, Sch Med, Hlth Sci Ctr, Dublin, Ireland. [Jahanshahi, Ali; Temel, Yasin] Maastricht Univ, Dept Neurosci, Maastricht, Netherlands. [Temel, Yasin] Maastricht Univ, Dept Neurosurg, Med Ctr, Maastricht, Netherlands. [Hendrix, Sven] Hasselt Univ, Dept Morphol, Biomed Res Inst BIOMED, Hasselt, Belgium. | - |
local.publisher.place | OXFORD | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1016/j.neubiorev.2017.10.021 | - |
dc.identifier.isi | 000419418700027 | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.fullcitation | Schoenfeld, Lisa-Maria; DOOLEY, Dearbhaile; Jahanshahi, Ali; Temel, Yasin & HENDRIX, Sven (2017) Evaluating rodent motor functions: Which tests to choose?. In: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 83, p. 298-312. | - |
item.contributor | Schoenfeld, Lisa-Maria | - |
item.contributor | DOOLEY, Dearbhaile | - |
item.contributor | Jahanshahi, Ali | - |
item.contributor | Temel, Yasin | - |
item.contributor | HENDRIX, Sven | - |
crisitem.journal.issn | 0149-7634 | - |
crisitem.journal.eissn | 1873-7528 | - |
Appears in Collections: | Research publications |
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schoenfeld 1.pdf Restricted Access | Published version | 574.09 kB | Adobe PDF | View/Open Request a copy |
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