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http://hdl.handle.net/1942/26353
Title: | Thrombo-embolic prevention after transcatheter aortic valve implantation | Authors: | VRANCKX, Pascal Windecker, Stephan Welsh, Robert C. Valgimigli, Marco Mehran, Roxana Dangas, George |
Issue Date: | 2017 | Publisher: | OXFORD UNIV PRESS | Source: | EUROPEAN HEART JOURNAL, 38(45), p. 3341-3350 | Abstract: | Transcatheter aortic valve implantation (TAVI) has emerged as a valuable treatment alternative to surgical aortic valve replacement among patients with symptomatic aortic stenosis at increased surgical risk. The rapid technological evolution from early to current-generation TAVI systems with low-profile delivery catheters, bioprosthetic valves with proven midterm durability, and improved positioning and retrieval features have made important contributions to the widespread clinical use of this minimal invasive therapy. Although peri-procedural and long-term thrombotic and bleeding events after TAVI remain a relevant concern, the optimal antithrombotic strategy and duration to mitigate these risks remain unclear. This review provides an overview of recent insights in this field, and highlights current and future antithrombotic trials focusing on optimizing outcomes in patients undergoing TAVI. | Notes: | [Vranckx, Pascal] Jessa Ziekenhuis, Hartctr Hasselt, Dept Cardiol & Crit Care Med, Stadsomvaart 11, B-3500 Hasselt, Belgium. [Vranckx, Pascal] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. [Windecker, Stephan; Valgimigli, Marco] Bern Univ Hosp, Swiss Cardiovasc Ctr Bern, Freiburgstr 8, CH-3010 Bern, Switzerland. [Welsh, Robert C.; Mehran, Roxana; Dangas, George] Univ Alberta, Mazankowski Alberta Heart Inst, 11220 83 Ave NW, Edmonton, AB T6G 2B7, Canada. Icahn Sch Med Mt Sinai, One Gustave L Levy Pl,Box 1030, New York, NY 10029 USA. | Keywords: | Aortic valve; TAVI; Anticoagulation;aortic valve; TAVI; anticoagulation | Document URI: | http://hdl.handle.net/1942/26353 | ISSN: | 0195-668X | e-ISSN: | 1522-9645 | DOI: | 10.1093/eurheartj/ehx390 | ISI #: | 000417194000007 | Rights: | (C) The Author 2017. For permissions, please email: journals.permissions@oup.com. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2018 |
Appears in Collections: | Research publications |
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