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Title: | Arenavirus infection correlates with lower survival of its natural rodent host in a long-term capture-mark-recapture study | Authors: | Marien, Joachim Sluydts, Vincent BORREMANS, Benny Gryseels, Sophie Broecke, Bram Vanden Sabuni, Christopher A. Katakweba, Abdul A. S. Mulungu, Loth S. Guenther, Stephan de Bellocq, Joelle Gouy Massawe, Apia W. Leirs, Herwig |
Issue Date: | 2018 | Source: | PARASITES & VECTORS, 11 (Art N° 90) | Abstract: | Background: Parasite evolution is hypothesized to select for levels of parasite virulence that maximise transmission success. When host population densities fluctuate, low levels of virulence with limited impact on the host are expected, as this should increase the likelihood of surviving periods of low host density. We examined the effects of Morogoro arenavirus on the survival and recapture probability of multimammate mice (Mastomys natalensis) using a seven-year capture-mark-recapture time series. Mastomys natalensis is the natural host of Morogoro virus and is known for its strong seasonal density fluctuations. Results: Antibody presence was negatively correlated with survival probability (effect size: 5-8% per month depending on season) but positively with recapture probability (effect size: 8%). Conclusions: The small negative correlation between host survival probability and antibody presence suggests that either the virus has a negative effect on host condition, or that hosts with lower survival probability are more likely to obtain Morogoro virus infection, for example due to particular behavioural or immunological traits. The latter hypothesis is supported by the positive correlation between antibody status and recapture probability which suggests that risky behaviour might increase the probability of becoming infected. | Notes: | Marien, J (reprint author), Univ Antwerp, Evolutionary Ecol Grp, Antwerp, Belgium. joachim.marien@uantwerpen.be | Keywords: | arenavirus; morogoro virus; survival analysis; capture-mark-recapture; host-parasite interaction | Document URI: | http://hdl.handle.net/1942/26438 | ISSN: | 1756-3305 | e-ISSN: | 1756-3305 | DOI: | 10.1186/s13071-018-2674-2 | ISI #: | 000424784300004 | Rights: | © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2019 |
Appears in Collections: | Research publications |
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