HPV DNA detection in urine: effect of a first-void urine collection device and time of collection

Abstract

Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV is not a sufficient cause, but it is a component cause of cervical cancer and genital warts (Lacy et al ., 2006). HPV can be detected in humans using samples from cervix or urine. The purpose of this studies is to evaluate the efficiency of a proptotype first-void urine collection device (Colli-Pee) against the standard collection cup and to assess the effect of time of collection on the detection of human and HPV DNA in women. The effect of human DNA on the detection of HPV DNA was also investigated. The dependency of the likelihood of positive HPV and the amount of HPV DNA was also investigated.