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http://hdl.handle.net/1942/27694
Title: | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes | Authors: | NEUPANE, Shova De Smet, Yana RENNER, Frank LOSADA-PEREZ, Patricia |
Issue Date: | 2018 | Publisher: | FRONTIERS MEDIA SA | Source: | Frontiers in Materials, 5 (Art N° 46) | Abstract: | Solid-supported lipid membranes are popular models that connect biological and artificial materials used in bio-technological applications. Controlling the lipid organization and the related functions of these model systems entails understanding and characterizing their phase behavior. Quartz crystal microbalance with dissipation monitoring (QCM-D) is an acoustic-based surface-sensitive technique which is widely used in bio-interfacial science of solid-supported lipid membranes. Its sensitivity to mass and energy dissipation changes at the solid-lipid layer-liquid interface allows the detection of phase transformations of solid-supported membrane geometries. In this perspective, we highlight this valuable feature and its related methodology, review current advances and briefly discuss future perspectives. Furthermore, a specific example is also provided on the ability of QCM-D to detect changes in lipid organization of cholesterol containing solid-supported lipid vesicle layers (SVLs) upon the addition of aspirin. | Notes: | [Neupane, Shova; De Smet, Yana; Renner, Frank U.] Hasselt Univ, Inst Mat Res, Diepenbeek, Belgium. [Neupane, Shova; Renner, Frank U.] IMEC VZW, Div IMOMEC, Diepenbeek, Belgium. [Losada-Perez, Patricia] Univ Libre Bruxelles, Soft Matter Phys Lab, Campus La Plaine, Brussels, Belgium. | Keywords: | QCM-D; model mebranes; phase transitions biological condensed matter; viscoelastic properties; biointerfaces;QCM-D; model mebranes; phase transitions biological condensed matter; viscoelastic properties; biointerfaces | Document URI: | http://hdl.handle.net/1942/27694 | ISSN: | 2296-8016 | e-ISSN: | 2296-8016 | DOI: | 10.3389/fmats.2018.00046 | ISI #: | 000441383300001 | Rights: | Copyright © 2018 Neupane, De Smet, Renner and Losada-Pérez. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2019 |
Appears in Collections: | Research publications |
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neupane 1.pdf | Published version | 1.3 MB | Adobe PDF | View/Open |
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