Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/29073
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Maron, Eva | - |
dc.contributor.author | Swisher, Jordan H. | - |
dc.contributor.author | HAVEN, Joris | - |
dc.contributor.author | Meyer, Tara Y. | - |
dc.contributor.author | JUNKERS, Tanja | - |
dc.contributor.author | Boerner, Hans G. | - |
dc.date.accessioned | 2019-08-30T09:42:49Z | - |
dc.date.available | 2019-08-30T09:42:49Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58 (31), p. 10747-10751 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/1942/29073 | - |
dc.description.abstract | Functional precision polymers based on monodisperse oligo(N-substituted acrylamide)s and oligo(2-substituted-alpha-hydroxy acid)s have been synthesized. The discrete sequences originate from a direct translation of side-chain functionality sequences of a peptide with well-studied properties. The peptide was previously selected to solubilize the photosensitizer meta-tetra(hydroxyphenyl)chlorin. The resulting peptidomimetic formulation additives preserve the drug solubilization and release characteristics of the parent peptide. In some cases, superior properties are obtained, reaching up to 40 % higher payloads and 27-times faster initial drug release. | - |
dc.description.sponsorship | H.G.B. acknowledges financial support by the European Research Council under the European Union's 7th Framework Program (FP07-13)/ERC Consolidator grant "Specifically Interacting Polymer-SIP" (ERC 305064). T.Y.M. acknowledges financial support from the National Science Foundation (CHE-1709144). Additional support for MALDI-TOF MS instrumentation was provided by a grant from the National Science Foundation (CHE-1625002). T.J. and J.J.H. are grateful for provision of the mass spectrometer through the Hercules fund Belgium. J.J.H. and T.J. thank J. Vandenbergh for contributing to the synthesis of the SUMI oligomers. | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.rights | 2019 Wiley-VCH Verlag GmbH&Co. KGaA,Weinheim | - |
dc.subject.other | drug deliverysystem; monodisperse polymers; peptide PEG conjugates; precision polymers; sequencedesign | - |
dc.subject.other | drug delivery system; monodisperse polymers; peptide PEG conjugates; precision polymers; sequence design | - |
dc.title | Learning from Peptides To Access Functional Precision Polymer Sequences | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 10751 | - |
dc.identifier.issue | 31 | - |
dc.identifier.spage | 10747 | - |
dc.identifier.volume | 58 | - |
local.format.pages | 5 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Maron, Eva; Boerner, Hans G.] Humboldt Univ, Dept Chem, Brook Taylor Str 2, D-12489 Berlin, Germany. [Swisher, Jordan H.; Meyer, Tara Y.] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA. [Haven, Joris J.; Junkers, Tanja] Monash Univ, Sch Chem, Polymer React Design Grp, 19 Rainforest Walk, Clayton, Vic 3800, Australia. [Junkers, Tanja] Hasselt Univ, Inst Mat Res, Martelarenlaan 42, B-3500 Hasselt, Belgium. | - |
local.publisher.place | WEINHEIM | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1002/anie.201902217 | - |
dc.identifier.isi | 000474091700001 | - |
item.fullcitation | Maron, Eva; Swisher, Jordan H.; HAVEN, Joris; Meyer, Tara Y.; JUNKERS, Tanja & Boerner, Hans G. (2019) Learning from Peptides To Access Functional Precision Polymer Sequences. In: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58 (31), p. 10747-10751. | - |
item.fulltext | With Fulltext | - |
item.contributor | Maron, Eva | - |
item.contributor | Swisher, Jordan H. | - |
item.contributor | HAVEN, Joris | - |
item.contributor | Meyer, Tara Y. | - |
item.contributor | JUNKERS, Tanja | - |
item.contributor | Boerner, Hans G. | - |
item.accessRights | Restricted Access | - |
crisitem.journal.issn | 1433-7851 | - |
crisitem.journal.eissn | 1521-3773 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
maron 1.pdf Restricted Access | Published version | 2.64 MB | Adobe PDF | View/Open Request a copy |
SCOPUSTM
Citations
7
checked on Sep 3, 2020
WEB OF SCIENCETM
Citations
31
checked on Sep 26, 2024
Page view(s)
168
checked on Sep 7, 2022
Download(s)
150
checked on Sep 7, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.