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http://hdl.handle.net/1942/29110
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DC Field | Value | Language |
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dc.contributor.author | Conte, Valeria | - |
dc.contributor.author | BIANCHI, Anna | - |
dc.contributor.author | Selva, Anna | - |
dc.contributor.author | Petringa, Giada | - |
dc.contributor.author | Cirrone, G. A. Pablo | - |
dc.contributor.author | Parisi, Alessio | - |
dc.contributor.author | Vanhavere, Filip | - |
dc.contributor.author | Colautti, Paolo | - |
dc.date.accessioned | 2019-09-06T13:48:06Z | - |
dc.date.available | 2019-09-06T13:48:06Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Physica Medica-European Journal of Medical Physics, 64(3), p. 114-122 | - |
dc.identifier.issn | 1120-1797 | - |
dc.identifier.uri | http://hdl.handle.net/1942/29110 | - |
dc.description.abstract | A new mini-TEPC with cylindrical sensitive volume of 0.9mm in diameter and height, and with external diameter of 2.7 mm, has been developed to work without gas flow. With such a mini counter we have measured the physical quality of the 62 MeV therapeutic proton beam of CATANA (Catania, Italy). Measurements were performed at six precise positions along the Spread-Out Bragg Peak (SOBP): 1.4, 19.4, 24.6, 29.0, 29.7 and 30.8 mm, corresponding to positions of clinical relevance (entrance, proximal, central, and distal-edge of the SOBP) or of high lineal energy transfer (LET) increment (distal-dose drop off). Without refilling the microdosimeter with new gas, the measurements were repeated at the same positions 4 months later, in order to study the stability of the response in sealed-mode operation. From the microdosimetric spectra the frequency-mean lineal energy yF and the dose-mean lineal energy yD were derived and compared with average LET values calculated by means of Geant4 simulations. The comparison points out, in particular, a good agreement between microdosimetric yD and the total dose-average LET_d, which is the average LET of the mixed radiation field, including the contribution by nuclear reactions. | - |
dc.description.sponsorship | This work was supported by the Italian Institute for Nuclear Physics(INFN). The Belgian nuclear research centre SCK·CEN and HasseltUniversity provide a Phd scholarship | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | 2019 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved | - |
dc.subject.other | TEPC; Microdosimetry; Proton therapy; Proton RBE | - |
dc.title | Microdosimetry at the CATANA 62 MeV proton beam with a sealed miniaturized TEPC | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 122 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 114 | - |
dc.identifier.volume | 64 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | - |
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[30] Pihet P, Menzel HG, Schmidt R, Beauduin M, Wambersie A. Biological weighting function for RBE specification of neutron therapy beams. Intercomparison of 9 European centres. Rad. Prot. Dosim. 1990;31(1-4):437–42. [31] Gueulette J, et al. Intestinal crypt regeneration in mice: A biological system for quality assurance in non-conventional radiation therapy. Radiother Oncol 2005;73(Suppl 2):S148–54. [32] Friedrich T, Scholz U, Elsässer T, Durante M, Scholz M. Systematic analysis of RBE and related quantities using a database of cell survival experiments with ion beam irradiation. J Radiat Res 2013;54(3):494–514. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.source.type | Article | - |
dc.identifier.doi | 10.1016/j.ejmp.2019.06.011 | - |
dc.identifier.isi | WOS:000485006200016 | - |
dc.identifier.eissn | - | |
local.provider.type | Web of Science | - |
item.validation | ecoom 2020 | - |
item.fulltext | With Fulltext | - |
item.contributor | Conte, Valeria | - |
item.contributor | BIANCHI, Anna | - |
item.contributor | Selva, Anna | - |
item.contributor | Petringa, Giada | - |
item.contributor | Cirrone, G. A. Pablo | - |
item.contributor | Parisi, Alessio | - |
item.contributor | Vanhavere, Filip | - |
item.contributor | Colautti, Paolo | - |
item.accessRights | Restricted Access | - |
item.fullcitation | Conte, Valeria; BIANCHI, Anna; Selva, Anna; Petringa, Giada; Cirrone, G. A. Pablo; Parisi, Alessio; Vanhavere, Filip & Colautti, Paolo (2019) Microdosimetry at the CATANA 62 MeV proton beam with a sealed miniaturized TEPC. In: Physica Medica-European Journal of Medical Physics, 64(3), p. 114-122. | - |
crisitem.journal.issn | 1120-1797 | - |
crisitem.journal.eissn | 1724-191X | - |
Appears in Collections: | Research publications |
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