Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/29967
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rothenbuehler, Martina | - |
dc.contributor.author | Valgimigli, Marco | - |
dc.contributor.author | Odutayo, Ayodele | - |
dc.contributor.author | Frigoli, Enrico | - |
dc.contributor.author | Leonardi, Sergio | - |
dc.contributor.author | VRANCKX, Pascal | - |
dc.contributor.author | Turturo, Maurizio | - |
dc.contributor.author | Moretti, Luciano | - |
dc.contributor.author | Amico, Francesco | - |
dc.contributor.author | Uguccioni, Lucia | - |
dc.contributor.author | Contarini, Marco | - |
dc.contributor.author | Antoni Gomez-Hospital, Joan | - |
dc.contributor.author | Mainar, Vicente | - |
dc.contributor.author | Creaco, Manuela | - |
dc.contributor.author | Petronio, Anna Sonia | - |
dc.contributor.author | Cremonesi, Alberto | - |
dc.contributor.author | Tamburino, Corrado | - |
dc.contributor.author | Fresco, Claudio | - |
dc.contributor.author | Bonmassari, Roberto | - |
dc.contributor.author | Diaz Fernandez, Jose Francisco | - |
dc.contributor.author | Romagnoli, Enrico | - |
dc.contributor.author | Beyersmann, Jan | - |
dc.contributor.author | Heg, Dik | - |
dc.contributor.author | Juni, Peter | - |
dc.date.accessioned | 2019-11-13T13:33:17Z | - |
dc.date.available | 2019-11-13T13:33:17Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | EUROPEAN HEART JOURNAL, 40(15), p. 1226-1232a | - |
dc.identifier.issn | 0195-668X | - |
dc.identifier.uri | http://hdl.handle.net/1942/29967 | - |
dc.description.abstract | Aims In the Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX (MATRIX) trial, adults with acute coronary syndrome undergoing coronary intervention who were allocated to radial access had a lower risk of bleeding, acute kidney injury (AKI), and all-cause mortality, as compared with those allocated to femoral access. The mechanism of the mortality benefit of radial access remained unclear. Methods and results We used multistate and competing risk models to determine the effects of radial and femoral access on bleeding, AKI and all-cause mortality in the MATRIX trial and to disentangle the relationship between these different types of events. There were large relative risk reductions in mortality for radial compared with femoral access for the transition from AKI to death [hazard ratio (HR) 0.55, 95% confidence interval (CI) 0.31-0.97] and for the pathway from coronary intervention to AKI to death (HR 0.49, 95% CI 0.26-0.92). Conversely, there was little evidence for a difference between radial and femoral groups for the transition from bleeding to death (HR 1.05, 95% CI 0.42-2.64) and the pathway from coronary intervention to bleeding to death (HR 0.84, 95% CI 0.28-2.49). Conclusion The prevention of AKI appeared predominantly responsible for the mortality benefit of radial as compared with femoral access in the MATRIX trial. There was little evidence for an equally important, independent role of bleeding. | - |
dc.description.sponsorship | The MATRIX programme was sponsored by the Italian Society of Invasive Cardiology (GISE), a non-profit organization, and received grant support from The Medicines Company and TERUMO. This research was completed, in part, with funding from the Canada Research Chairs Programme to P.J. | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.rights | The Author(s) 2019 | - |
dc.subject.other | Acute coronary syndrome; Percutaneous coronary intervention; Multistate model; Competing risk model | - |
dc.subject.other | Acute coronary syndrome; Percutaneous coronary intervention; Multistate model; Competing risk model | - |
dc.title | Association of acute kidney injury and bleeding events with mortality after radial or femoral access in patients with acute coronary syndrome undergoing invasivemanagement: secondary analysis of a randomized clinical trial | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1232a | - |
dc.identifier.issue | 15 | - |
dc.identifier.spage | 1226 | - |
dc.identifier.volume | 40 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Rothenbuehler, Martina; Frigoli, Enrico; Heg, Dik] Univ Bern, CTU Bern, Mittelstr 43, CH-3012 Bern, Switzerland. [Rothenbuehler, Martina; Frigoli, Enrico; Heg, Dik] Univ Bern, ISPM, Mittelstr 43, CH-3012 Bern, Switzerland. [Valgimigli, Marco] Bern Univ Hosp, Swiss Cardiovasc Ctr Bern, Freiburgstr 8, CH-3010 Bern, Switzerland. [Odutayo, Ayodele; Juni, Peter] Univ Toronto, Dept Med, St Michaels Hosp, Appl Hlth Res Ctr,Li Ka Shing Knowledge Inst, 30 Bond St, Toronto, ON M5B 1W8, Canada. [Odutayo, Ayodele; Juni, Peter] Univ Toronto, Inst Hlth Policy Management & Evaluat, 30 Bond St, Toronto, ON M5B 1W8, Canada. [Leonardi, Sergio] Fdn IRCCS Policlin San Matteo, Coronary Care Unit, Viale Golgi 19, I-27100 Pavia, Italy. [Vranckx, Pascal] Jessa Ziekenhuis, Hartctr Hasselt, Dept Cardiol & Crit Care Med, Stadsomvaart 11, B-3500 Hasselt, Belgium. [Vranckx, Pascal] Univ Hasselt, Fac Med & Life Sci, Martelarenlaan 42, B-3500 Hasselt, Belgium. [Turturo, Maurizio] Div Cardiol, PO Di Venere,Via Osped Venere 1, I-70131 Bari, Italy. [Moretti, Luciano] Mazzoni Hosp, Div Cardiol, Via Iris, I-63100 Ascoli Piceno, Italy. [Amico, Francesco] S Elia Hosp, Cardiol Unit, Via Luigi Russo 6, I-93100 Caltanissetta, Italy. [Uguccioni, Lucia] Osped Riuniti Marche Nord, Intervent Cardiol, Piazzale Cinelli 4, I-61121 Pesaro, Italy. [Contarini, Marco] Umberto I Hosp, Intervent Cardiol Unit, Via Testaferrata 1, I-96100 Siracusa, Italy. [Antoni Gomez-Hospital, Joan] Bellvitge Univ Hosp, Heart Dis Inst, Feixa Uarga S-N, Barcelona 08907, Spain. [Mainar, Vicente] Hosp Gen Alicante, Dept Cardiol, Pintor Baeza 11, Alicante 03010, Spain. [Creaco, Manuela] Gravina Hosp, Cardiol Unit, Via Portosalvo 9, I-95041 Caltagirone, Italy. [Petronio, Anna Sonia] Univ Pisa, Osped Cisanello, Cardiothorac & Vasc Dept, Unit Intervent Cardiol, Via Paradisa 2, I-56124 Pisa, Italy. [Cremonesi, Alberto] Humanitas Gavazzeni Hosp, Cardiovasc Dept, Via M Gavazzeni 21, I-24125 Bergamo, Italy. [Tamburino, Corrado] CAST Policlin Univ Hosp, Cardiothorax Vasc & Transplant Dept, Cardiol Div, Via S Sofia 76, I-95123 Catania, Italy. [Fresco, Claudio] Azienda Sanit Univ Integrata Udine, Cardiol Unit, Piazzale S Maria della Misericordia 15, I-33100 Udine, Italy. [Bonmassari, Roberto] Santa Chiara Hosp, Div Cardiol, Largo Medaglie Doro 9, I-38122 Trento, Italy. [Diaz Fernandez, Jose Francisco] Juan Ramon Jimenez Univ Hosp, Intervent Cardiol Dept, Ronda Norte Sn, Huelva 21005, Spain. [Romagnoli, Enrico] Fdn Policlin Univ A Gemelli, Dept Cardiol, Largo Agostino Gemelli 8, I-00168 Rome, Italy. [Beyersmann, Jan] Ulm Univ, Inst Stat, Helmholtzstr 20, D-89081 Ulm, Germany. | - |
local.publisher.place | OXFORD | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1093/eurheartj/ehy860 | - |
dc.identifier.isi | 000490013100017 | - |
item.fullcitation | Rothenbuehler, Martina; Valgimigli, Marco; Odutayo, Ayodele; Frigoli, Enrico; Leonardi, Sergio; VRANCKX, Pascal; Turturo, Maurizio; Moretti, Luciano; Amico, Francesco; Uguccioni, Lucia; Contarini, Marco; Antoni Gomez-Hospital, Joan; Mainar, Vicente; Creaco, Manuela; Petronio, Anna Sonia; Cremonesi, Alberto; Tamburino, Corrado; Fresco, Claudio; Bonmassari, Roberto; Diaz Fernandez, Jose Francisco; Romagnoli, Enrico; Beyersmann, Jan; Heg, Dik & Juni, Peter (2019) Association of acute kidney injury and bleeding events with mortality after radial or femoral access in patients with acute coronary syndrome undergoing invasivemanagement: secondary analysis of a randomized clinical trial. In: EUROPEAN HEART JOURNAL, 40(15), p. 1226-1232a. | - |
item.contributor | Rothenbuehler, Martina | - |
item.contributor | Valgimigli, Marco | - |
item.contributor | Odutayo, Ayodele | - |
item.contributor | Frigoli, Enrico | - |
item.contributor | Leonardi, Sergio | - |
item.contributor | VRANCKX, Pascal | - |
item.contributor | Turturo, Maurizio | - |
item.contributor | Moretti, Luciano | - |
item.contributor | Amico, Francesco | - |
item.contributor | Uguccioni, Lucia | - |
item.contributor | Contarini, Marco | - |
item.contributor | Antoni Gomez-Hospital, Joan | - |
item.contributor | Mainar, Vicente | - |
item.contributor | Creaco, Manuela | - |
item.contributor | Petronio, Anna Sonia | - |
item.contributor | Cremonesi, Alberto | - |
item.contributor | Tamburino, Corrado | - |
item.contributor | Fresco, Claudio | - |
item.contributor | Bonmassari, Roberto | - |
item.contributor | Diaz Fernandez, Jose Francisco | - |
item.contributor | Romagnoli, Enrico | - |
item.contributor | Beyersmann, Jan | - |
item.contributor | Heg, Dik | - |
item.contributor | Juni, Peter | - |
item.accessRights | Restricted Access | - |
item.validation | ecoom 2020 | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 0195-668X | - |
crisitem.journal.eissn | 1522-9645 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
rothenbuhler 1.pdf Restricted Access | Published version | 1.3 MB | Adobe PDF | View/Open Request a copy |
SCOPUSTM
Citations
8
checked on Sep 3, 2020
WEB OF SCIENCETM
Citations
26
checked on Aug 19, 2024
Page view(s)
84
checked on Jul 20, 2022
Download(s)
66
checked on Jul 20, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.