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Title: | Periodized home-based training: A new strategy to improve high intensity exercise therapy adherence in mildly affected patients with Multiple Sclerosis | Authors: | KEYTSMAN, Charly VAN NOTEN, Pieter SPAAS, Jan NIESTE, Ine VAN ASCH, Paul OP 'T EIJNDE, Bert |
Issue Date: | 2019 | Publisher: | ELSEVIER SCI LTD | Source: | MULTIPLE SCLEROSIS AND RELATED DISORDERS, 28, p. 91-97 | Abstract: | Introduction: Although high intensity exercise therapy (HIT) in Multiple Sclerosis (MS) induces substantial effects, longer term compliance to such a training program is not evident. When embedded in a periodized, home-based training strategy, high intensity exercise therapy adherence may improve. This is explored first in mildly affected persons with MS. Methods: Exercise capacity (maximal exercise test) and body composition (DEXA) of healthy controls (n = 22) and persons with MS (n = 23, EDSS: 1.9 +/- 1.1) were assessed at baseline (PRE). Next and within the context of an MS awareness project (climbing the Mont Ventoux, France), all participants were enrolled in a 6 m home-based periodized HIT oriented cycling program with remote (Polar (R) M200 activity tracker) supervision. Hereafter, POST measurements were performed similar to baseline. Results: Six months of periodized and home-based HIT oriented training induced improvements in body weight ( - 3%, p = 0.008), BMI ( - 3%, p = 0.01), total mass ( - 2%, p = 0.023), VO2max (+ 5%, p = 0.016), workload (+ 11%, p = 0.001), time until exhaustion (+ 14%, p = 0.001), recovery heart rate (+ 4%, p = 0.04), lactate peak ( + 16%, p = 0.03) and RER (+ 4%, p = 0.04) in MS. Furthermore, all persons with MS safely reached the top of the Mont Ventoux, except for two. Conclusion: The applied 6 m periodized, home-based and HIT-oriented cycling program provided good therapy adherence with similar improvements in exercise capacity compared to healthy controls. Furthermore, this exercise regimen trained mildly-affected persons with MS adequately to climb the Mont Ventoux. | Notes: | [Keytsman, Charly; Van Noten, Pieter; Spaas, Jan; Nieste, Ine; Eijnde, Bert O.] Hasselt Univ, Fac Med & Life Sci, REVAL Rehabil Res Ctr, Biomed Res Inst BIOMED, Agoralaan Bldg A, B-3590 Diepenbeek, Belgium. [Van Asch, Paul] Move Sport Fdn, Mechelsesteenweg, Kontich, Belgium. | Document URI: | http://hdl.handle.net/1942/30312 | ISSN: | 2211-0348 | e-ISSN: | 2211-0356 | DOI: | 10.1016/j.msard.2018.12.018 | ISI #: | 000459833100018 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2020 |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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keytsman 1.pdf Restricted Access | Published version | 708.61 kB | Adobe PDF | View/Open Request a copy |
20181125 Clean version - MSARD.pdf | Peer-reviewed author version | 385.88 kB | Adobe PDF | View/Open |
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