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http://hdl.handle.net/1942/30328
Title: | Semiparametric linear transformation models: Effect measures, estimators, and applications | Authors: | De Neve, Jan THAS, Olivier Gerds, Thomas A. |
Issue Date: | 2019 | Publisher: | WILEY | Source: | STATISTICS IN MEDICINE, 38(8), p. 1484-1501 | Abstract: | Semiparametric linear transformation models form a versatile class of regression models with the Cox proportional hazards model being the most well-known member. These models are well studied for right censored outcomes and are typically used in survival analysis. We consider transformation models as a tool for situations with uncensored continuous outcomes where linear regression is not appropriate. We introduce the probabilistic index as a uniform effect measure for the class of transformation models. We discuss and compare three estimators using a working Cox regression model: the partial likelihood estimator, an estimator based on binary generalized linear models and one based on probabilistic index model estimating equations. The latter has a superior performance in terms of bias and variance when the working model is misspecified. For the purpose of illustration, we analyze data that were collected at an urban alcohol and drug detoxification unit. | Notes: | [De Neve, Jan] Univ Ghent, Dept Data Anal, Henri Dunantlaan 2, B-9000 Ghent, Belgium. [Thas, Olivier] Hasselt Univ, Ctr Stat, Diepenbeek, Belgium. [Thas, Olivier] Univ Wollongong, Natl Inst Appl Stat Res Australia, Wollongong, NSW, Australia. [Gerds, Thomas A.] Univ Copenhagen, Dept Biostat, Copenhagen, Denmark. | Keywords: | probabilistic index;proportional hazard model;proportional odds model;semiparametric regression | Document URI: | http://hdl.handle.net/1942/30328 | ISSN: | 0277-6715 | e-ISSN: | 1097-0258 | DOI: | 10.1002/sim.8078 | ISI #: | 000460319700013 | Rights: | 2019 John Wiley & Sons, Ltd. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2020 |
Appears in Collections: | Research publications |
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