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http://hdl.handle.net/1942/30363
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DC Field | Value | Language |
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dc.contributor.author | VONCK, Sharona | - |
dc.contributor.author | Staelens, Anneleen Simone | - |
dc.contributor.author | LANSSENS, Dorien | - |
dc.contributor.author | TOMSIN, Kathleen | - |
dc.contributor.author | OBEN, Jolien | - |
dc.contributor.author | DREESEN, Pauline | - |
dc.contributor.author | BRUCKERS, Liesbeth | - |
dc.contributor.author | GYSELAERS, Wilfried | - |
dc.date.accessioned | 2020-01-22T07:53:33Z | - |
dc.date.available | 2020-01-22T07:53:33Z | - |
dc.date.issued | 2019 | - |
dc.date.submitted | 2020-01-20T08:56:13Z | - |
dc.identifier.citation | FETAL DIAGNOSIS AND THERAPY, 46 (4) , p. 238 -245 | - |
dc.identifier.issn | 1015-3837 | - |
dc.identifier.uri | http://hdl.handle.net/1942/30363 | - |
dc.description.abstract | Background: Pregnancies complicated with small for gestational age (SGA) neonates are reported with maternal circulatory maladaptations. Objectives: We aimed to understand the pathophysiology of the maternal circulation in normotensive SGA pregnancies and to point out the trimestral differences from those with appropriate-to-large (non-SGA [NGA]) neonates. Methods: An observational study was conducted in 3 trimestral cohorts of normotensive pregnancies, categorized after birth according to neonatal birth weight percentile (BW%) as SGA (BW% <= 10, n = 158) or NGA (BW% > 10, n = 1,038). Standardized electrocardiogram-Doppler ultrasound, impedance cardiography, and bio-impedance were used to assess the maternal heart, arteries, veins, and fluid. Results: Diastolic blood pressure and mean arterial pressure were not significantly different, unless in the third trimester. In SGA compared to NGA pregnancies, total peripheral resistance (TPR) was higher and total arterial compliance, cardiac output (CO), and total body water (TBW) were lower throughout pregnancy. Venous return-enhancing functions were activated. In NGA but not SGA pregnancies, a positive correlation was found between BW% and CO + TBW and a negative correlation between BW% and TPR. Conclusions: SGA pregnancies are characterized by lower maternal body fluid volume and CO, while normal blood pressures are maintained via increased TPR already from the first trimester onwards. Pregnancy-induced hemodynamic changes are superimposed on these characteristics. | - |
dc.description.sponsorship | Agency for Innovation by Science and Technology (IWT) in Brussels, BelgiumInstitute for the Promotion of Innovation by Science and Technology in Flanders (IWT) | - |
dc.language.iso | en | - |
dc.publisher | KARGER | - |
dc.rights | 2019 S. Karger AG, Basel | - |
dc.subject.other | Small for gestational age | - |
dc.subject.other | Maternal hemodynamics | - |
dc.subject.other | Pregnancy | - |
dc.subject.other | Pathophysiology | - |
dc.title | Low Volume Circulation in Normotensive Women Pregnant with Neonates Small for Gestational Age | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 245 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 238 | - |
dc.identifier.volume | 46 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Vonck, S (reprint author), Ziekenhuis Oost Limburg, Dept Obstet & Gynaecol, Schiepse Bos 6, BE-3600 Genk, Belgium. | - |
dc.description.notes | sharonavonck@hotmail.com | - |
local.publisher.place | ALLSCHWILERSTRASSE 10, CH-4009 BASEL, SWITZERLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.source.type | Article | - |
dc.identifier.doi | 10.1159/000495507 | - |
dc.identifier.pmid | 30726847 | - |
dc.identifier.isi | WOS:000492976400004 | - |
dc.identifier.eissn | 1421-9964 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
item.contributor | VONCK, Sharona | - |
item.contributor | Staelens, Anneleen Simone | - |
item.contributor | LANSSENS, Dorien | - |
item.contributor | TOMSIN, Kathleen | - |
item.contributor | OBEN, Jolien | - |
item.contributor | DREESEN, Pauline | - |
item.contributor | BRUCKERS, Liesbeth | - |
item.contributor | GYSELAERS, Wilfried | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2020 | - |
item.fullcitation | VONCK, Sharona; Staelens, Anneleen Simone; LANSSENS, Dorien; TOMSIN, Kathleen; OBEN, Jolien; DREESEN, Pauline; BRUCKERS, Liesbeth & GYSELAERS, Wilfried (2019) Low Volume Circulation in Normotensive Women Pregnant with Neonates Small for Gestational Age. In: FETAL DIAGNOSIS AND THERAPY, 46 (4) , p. 238 -245. | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 1015-3837 | - |
crisitem.journal.eissn | 1421-9964 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Revised Manuscript_clean.pdf | Peer-reviewed author version | 196.63 kB | Adobe PDF | View/Open |
published version.pdf Restricted Access | Published version | 291.4 kB | Adobe PDF | View/Open Request a copy |
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