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http://hdl.handle.net/1942/30388
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DC Field | Value | Language |
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dc.contributor.author | BATEN, Evert | - |
dc.contributor.author | Van der Aa, F. | - |
dc.contributor.author | Orye, C. | - |
dc.contributor.author | Cartuyvels, R. | - |
dc.contributor.author | ARIJS, Ingrid | - |
dc.contributor.author | VAN RENTERGHEM, Koenraad | - |
dc.date.accessioned | 2020-01-24T09:20:48Z | - |
dc.date.available | 2020-01-24T09:20:48Z | - |
dc.date.issued | 2019 | - |
dc.date.submitted | 2020-01-23T10:23:12Z | - |
dc.identifier.citation | WORLD JOURNAL OF UROLOGY, 37 (11) , p. 2467 -2472 | - |
dc.identifier.uri | http://hdl.handle.net/1942/30388 | - |
dc.description.abstract | Purpose Antibiotic prophylaxis is standard procedure in transurethral resection of the prostate (TURP). We evaluated the necessity of antibiotic (AB) prophylaxis in TURP due to increasing microbial antibiotic resistance. Methods This is a prospective cohort study of 506 patients. Only patients with a pre-operative catheter/pyuria received AB-prophylaxis. Urine analysis (pre-operative, at discharge, and 3 week post-operative) was performed next to an analysis of the blood culture/irrigation fluid and of the resected prostatic tissue. Statistical analysis was performed using Fisher's exact test. Results 67/506 (13.2%) patients received prophylactic antibiotics. 56/67 (83.5%) patients had a pre-operative catheter and 11/67 (16.4%) had pre-operative pyuria in which a fluoroquinolone-resistance (FQ-R) rate of 69.2% in Escherichia coli (EC) was observed. Clinical infectious symptoms were present in 13/439 (2.9%) patients without antibiotic prophylaxis; 12/439 (2.7%) patients had uncomplicated fever (<38.5 degrees) during or after hospitalization and only 1/439 patient (0.2%) was high degree fever (> 38.5 degrees) observed. Uncomplicated fever developed in 7/67 (10.4%) patients who did receive AB-prophylaxis. FQ-R was observed in 60% of the positive urine cultures at discharge and in 53.8% 3 week post-operatively. Conclusions Our data show a low infectious complication rate (2.9%) in patients without a pre-operative catheter or pyuria,undergoing TURP without AB-prophylaxis. These findings might question the current use of AB prophylaxis in TURP in patients without a pre-operative catheter or pyuria, in times of antibiotic stewardship due to the high rate of microbial-resistance in our population. | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.subject.other | TURP | - |
dc.subject.other | Antibiotics | - |
dc.subject.other | Microbial resistance | - |
dc.subject.other | Bacteriuria | - |
dc.title | Antibiotic prophylaxis in TURP: a prospective analysis concerning antibiotic stewardship and a potential reduction of antibiotic use in TURP | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 2472 | - |
dc.identifier.issue | 11 | - |
dc.identifier.spage | 2467 | - |
dc.identifier.volume | 37 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Baten, E (reprint author), Jessa Hosp, B-3050 Hasselt, Belgium.; Baten, E (reprint author), UZ Leuven, Herestr, B-3000 Leuven, Belgium. | - |
local.publisher.place | 233 SPRING ST, NEW YORK, NY 10013 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1007/s00345-019-02676-z | - |
dc.identifier.isi | WOS:000493686100023 | - |
dc.identifier.eissn | - | |
dc.identifier.eissn | 1433-8726 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
item.fulltext | With Fulltext | - |
item.contributor | BATEN, Evert | - |
item.contributor | Van der Aa, F. | - |
item.contributor | Orye, C. | - |
item.contributor | Cartuyvels, R. | - |
item.contributor | ARIJS, Ingrid | - |
item.contributor | VAN RENTERGHEM, Koenraad | - |
item.accessRights | Restricted Access | - |
item.validation | ecoom 2020 | - |
item.fullcitation | BATEN, Evert; Van der Aa, F.; Orye, C.; Cartuyvels, R.; ARIJS, Ingrid & VAN RENTERGHEM, Koenraad (2019) Antibiotic prophylaxis in TURP: a prospective analysis concerning antibiotic stewardship and a potential reduction of antibiotic use in TURP. In: WORLD JOURNAL OF UROLOGY, 37 (11) , p. 2467 -2472. | - |
crisitem.journal.issn | 0724-4983 | - |
crisitem.journal.eissn | 1433-8726 | - |
Appears in Collections: | Research publications |
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Baten2019_Article_AntibioticProphylaxisInTURPAPr.pdf Restricted Access | Published version | 573.62 kB | Adobe PDF | View/Open Request a copy |
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