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http://hdl.handle.net/1942/30398
Title: | Case report of delayed seroprotection rather than non-response after primary three-dose hepatitis B vaccination | Authors: | KOC, Ozgur Damoiseaux, Jan van Loo, Inge H.M. Masquillier, Heloise I.L. Oude Lashof, Astrid M.L. |
Issue Date: | 2020 | Publisher: | ELSEVIER SCI LTD | Source: | VACCINE, 38 (2) , p. 112 -114 | Abstract: | We describe a delayed hepatitis B seroprotection 12 weeks after the primary vaccination schedule in a 57-year-old male with smoldering multiple myeloma. Based on undetectable anti-HBs antibodies 6 weeks after the third vaccination, the index person was previously considered to be a hepatitis B vaccine non-responder. Because hepatitis B vaccination started in the 1980s, many hepatitis B vaccine non-responders have received a revaccination regimen. If more cases of genuine delayed hepatitis B seroprotection surface in patients with hematologic malignancies, delayed seroprotection should be considered before the commencement of hepatitis B revaccination. | Keywords: | Hepatitis B;Vaccine;Non-responder;Humoral Immunity;Delayed seroprotection | Document URI: | http://hdl.handle.net/1942/30398 | ISSN: | 0264-410X | e-ISSN: | 1873-2518 | DOI: | 10.1016/j.vaccine.2019.10.022 | ISI #: | WOS:000509612700003 | Rights: | Copyright 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2021 |
Appears in Collections: | Research publications |
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1-s2.0-S0264410X19313854-main.pdf | Published version | 238.81 kB | Adobe PDF | View/Open |
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