Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/30599
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDIERCKX, Tess-
dc.contributor.authorBOGIE, Jeroen-
dc.contributor.authorHENDRIKS, Jerome-
dc.date.accessioned2020-02-25T13:35:50Z-
dc.date.available2020-02-25T13:35:50Z-
dc.date.issued2019-
dc.date.submitted2020-02-20T11:03:44Z-
dc.identifier.citationCURRENT MEDICINAL CHEMISTRY, 26 (37) , p. 6750 -6765-
dc.identifier.urihttp://hdl.handle.net/1942/30599-
dc.description.abstractThe central nervous system (CNS) is the most cholesterol-rich organ in mammals. Cholesterol homeostasis is essential for proper brain functioning and dysregulation of cholesterol metabolism can lead to neurological problems. Multiple sclerosis (MS) and Alzheimer's disease (AD) are examples of neurological diseases that are characterized by a disturbed cholesterol metabolism. Phytosterols (PS) are plant-derived components that structurally and functionally resemble cholesterol. PS are known for their cholesterol-lowering properties. Due to their ability to reach the brain, researchers have started to investigate the physiological role of PS in the CNS. In this review, the metabolism and function of PS in the diseased and healthy CNS are discussed.-
dc.description.sponsorshipThis work was supported by grants of the Research Foundation Flanders (FWO; 12J9116N, 12JG119N, and G099618N to Tess Dierckx, Jeroen F.J. Bogie and Jerome J.A. Hendriks).-
dc.language.isoen-
dc.publisherBENTHAM SCIENCE PUBL LTD-
dc.rights2019 Bentham Science Publishers-
dc.subject.otherPhytosterols-
dc.subject.othercholesterol-
dc.subject.othercentral nervous system-
dc.subject.othermultiple sclerosis-
dc.subject.otherAlzheimer's disease-
dc.subject.otheradd-on therapy-
dc.titleThe Impact of Phytosterols on the Healthy and Diseased Brain-
dc.typeJournal Contribution-
dc.identifier.epage6765-
dc.identifier.issue37-
dc.identifier.spage6750-
dc.identifier.volume26-
local.format.pages16-
local.bibliographicCitation.jcatA1-
dc.description.notesHendriks, JJA (reprint author), Hasselt Univ, Biomed Res Inst, Diepenbeek, Hassett, Belgium.-
dc.description.notesjerome.hendriks@uhasselt.be-
dc.description.otherHendriks, JJA (reprint author), Hasselt Univ, Biomed Res Inst, Diepenbeek, Hassett, Belgium. jerome.hendriks@uhasselt.be-
local.publisher.placeEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB-
local.publisher.placeEMIRATES-
local.type.refereedRefereed-
local.type.specifiedReview-
dc.identifier.doi10.2174/0929867325666180706113844-
dc.identifier.isiWOS:000503163900006-
dc.identifier.eissn-
dc.identifier.eissn1875-533X-
local.provider.typewosris-
local.uhasselt.uhpubyes-
item.fulltextNo Fulltext-
item.accessRightsClosed Access-
item.fullcitationDIERCKX, Tess; BOGIE, Jeroen & HENDRIKS, Jerome (2019) The Impact of Phytosterols on the Healthy and Diseased Brain. In: CURRENT MEDICINAL CHEMISTRY, 26 (37) , p. 6750 -6765.-
item.contributorDIERCKX, Tess-
item.contributorBOGIE, Jeroen-
item.contributorHENDRIKS, Jerome-
crisitem.journal.issn0929-8673-
crisitem.journal.eissn1875-533X-
Appears in Collections:Research publications
Show simple item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.