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http://hdl.handle.net/1942/30831
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DC Field | Value | Language |
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dc.contributor.author | NIJST, Petra | - |
dc.contributor.author | MARTENS, Pieter | - |
dc.contributor.author | VERBRUGGE, Frederik | - |
dc.contributor.author | DUPONT, Matthias | - |
dc.contributor.author | Tang, W. H. Wilson | - |
dc.contributor.author | MULLENS, Wilfried | - |
dc.date.accessioned | 2020-03-18T13:35:03Z | - |
dc.date.available | 2020-03-18T13:35:03Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-03-17T11:34:19Z | - |
dc.identifier.citation | JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 13(4), p. 519-527 | - |
dc.identifier.issn | 1937-5387 | - |
dc.identifier.uri | http://hdl.handle.net/1942/30831 | - |
dc.description.abstract | This study aimed to investigate the relationship between intravascular volume and intracardiac filling pressures in stable HF patients with reduced ejection fraction (HFrEF). A total of 40 HFrEF patients (LVEF 36 +/- 10%) (10 subjects with a pulmonary artery catheter) underwent intravascular volume expansion with 1 L hydroxyl-ethyl-starch over 3 h with coinciding intravascular volume measurements (technetium (99 tc)-labeled red blood cell technique). Intravascular blood volume increased from 5.0 +/- 1.0 L to 5.7 +/- 1.0 L (p < 0.0001). No change in clinical status, echocardiographic indices, or cardiac filling pressures was noticed. Invasively measured right atrial pressure and pulmonary arterial wedge pressure increased significantly immediately after start of infusion (4 +/- 2 mmHg to 8 +/- 4 mmHg; p = 0.01 and 10 +/- 3 mmHg to 15 +/- 6 mmHg; p = 0.01, respectively), decreased afterwards, and remained stable for 3 h (6 +/- 2 mmHg and 14 +/- 4 mmHg, respectively). The accuracy of cardiac filling pressure estimates to predict intravascular volume expansion was low (all AUC < 0.65). | - |
dc.description.sponsorship | P.N is supported by The Frans Van de Werf Fund for Clinical Cardiovascular Research. P.N., P.M., and W.M. are researchers for the Limburg Clinical Research Program (LCRP) UHasselt-ZOL-Jessa, supported by the foundation Limburg Sterk Merk (LSM), Hasselt University, Ziekenhuis Oost-Limburg, and Jessa Hospital. P.N. and M.D. are supported by a research grant provided by Vision4Life-Sciences. | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.rights | Springer Science+Business Media, LLC, part of Springer Nature 2020 | - |
dc.subject.other | Central venous pressure | - |
dc.subject.other | Echocardiography | - |
dc.subject.other | Plasma volume | - |
dc.subject.other | Pulmonary wedge pressure | - |
dc.subject.other | Systolic heart failure | - |
dc.subject.other | Congestion | - |
dc.title | Cardiovascular Volume Reserve in Patients with Heart Failure and Reduced Ejection Fraction | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 527 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 519 | - |
dc.identifier.volume | 13 | - |
local.format.pages | 9 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Nijst, P (reprint author), Ziekenhuis Oost Limburg, Dept Cardiol, Schiepse Bos 6, B-3600 Genk, Belgium.; Nijst, P (reprint author), Hasselt Univ, Doctoral Sch Med & Life Sci, Diepenbeek, Belgium. | - |
dc.description.notes | petranijst@gmail.com | - |
dc.description.other | Nijst, P (reprint author), Ziekenhuis Oost Limburg, Dept Cardiol, Schiepse Bos 6, B-3600 Genk, Belgium, Hasselt Univ, Doctoral Sch Med & Life Sci, Diepenbeek, Belgium. petranijst@gmail.com | - |
local.publisher.place | ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.source.type | Article | - |
dc.identifier.doi | 10.1007/s12265-020-09973-8 | - |
dc.identifier.pmid | 32100209 | - |
dc.identifier.isi | WOS:000515917200001 | - |
dc.identifier.eissn | 1937-5395 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.uhasselt.international | yes | - |
item.contributor | NIJST, Petra | - |
item.contributor | MARTENS, Pieter | - |
item.contributor | VERBRUGGE, Frederik | - |
item.contributor | DUPONT, Matthias | - |
item.contributor | Tang, W. H. Wilson | - |
item.contributor | MULLENS, Wilfried | - |
item.fullcitation | NIJST, Petra; MARTENS, Pieter; VERBRUGGE, Frederik; DUPONT, Matthias; Tang, W. H. Wilson & MULLENS, Wilfried (2020) Cardiovascular Volume Reserve in Patients with Heart Failure and Reduced Ejection Fraction. In: JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 13(4), p. 519-527. | - |
item.accessRights | Restricted Access | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2021 | - |
crisitem.journal.issn | 1937-5387 | - |
crisitem.journal.eissn | 1937-5395 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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s12265-020-09973-8 (1).pdf Restricted Access | Published version | 672.1 kB | Adobe PDF | View/Open Request a copy |
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