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http://hdl.handle.net/1942/31067
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DC Field | Value | Language |
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dc.contributor.author | BUSSCHOTS, Dana | - |
dc.contributor.author | Toghanian, Samira | - |
dc.contributor.author | BIELEN, Rob | - |
dc.contributor.author | Salomonsson, Stina | - |
dc.contributor.author | KOC, Ozgur | - |
dc.contributor.author | Hendrickx, Greet | - |
dc.contributor.author | Jadoul, Michel | - |
dc.contributor.author | Nevens, Frederik | - |
dc.contributor.author | Sokal, Etienne | - |
dc.contributor.author | Brixko, Christian | - |
dc.contributor.author | Peerlinck, Kathelijne | - |
dc.contributor.author | Apers, Ludwig | - |
dc.contributor.author | ROBAEYS, Geert | - |
dc.contributor.author | Lazarus, Jeffrey V. | - |
dc.date.accessioned | 2020-04-21T14:20:37Z | - |
dc.date.available | 2020-04-21T14:20:37Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-04-13T12:37:17Z | - |
dc.identifier.citation | BMC INFECTIOUS DISEASES, 20 (Art N° 181) | - |
dc.identifier.uri | http://hdl.handle.net/1942/31067 | - |
dc.description.abstract | BackgroundHepatitis C virus is one of the leading causes of chronic liver disease and liver-related deaths worldwide. The estimated prevalence of chronic hepatitis C viral infection among the general Belgian population was 0.57% (n=64,000) in 2015. Although Belgium has had a 'Hepatitis C Plan' since 2014, elimination efforts are unclear. This study employs the best available data and modelling estimates to define the burden of hepatitis C viral infection among key subgroups in Belgium, identify information gaps and propose potential approaches to screening, linkage to care and treatment, and cure.MethodsWe examined the peer-reviewed and grey literature since 2012 for data on the prevalence of hepatitis C viral infection in Belgium in key subgroups identified by national experts and in the literature. Ultimately, this research is primarily based on data provided by the key stakeholders themselves due to a lack of reliable data in the literature. Based on this, we modelled the treatment rates required to reach elimination of hepatitis C in several subgroups.ResultsEleven potential subgroups were identified. There were no data available for two subgroups: generational cohorts and men who have sex with men. In six subgroups, fewer than 3000 people were reported or estimated to have hepatitis C infection. Migrants and people who inject drugs were the most affected subgroups, and children were the least affected subgroup. Only two subgroups are on target to achieve elimination by 2030: patients living with haemophilia and transplant recipients.ConclusionsRemoving Belgian treatment reimbursement restrictions in January 2019 was a big step towards eliminating HCV. In addition, increasing surveillance, including with a national registry, treatment prescription by other health-care providers and availability of treatment in local pharmacies are central to improving the current situation and getting on track to reach the 2030 WHO hepatitis C elimination targets in Belgium. | - |
dc.description.sponsorship | The PhD authors of this review are part of the `Limburg Clinical Research Center (LCRC), supported by the foundation Limburg Sterk Merk, province of Limburg, Flemish government, Hasselt University, Ziekenhuis Oost-Limburg and Jessa Hospital. JVL is supported by a Spanish Ministry of Science, Innovation and Universities Miguel Servet grant (Instituto de Salud III/ESF, European Union (CP18/00074)). This paper drew on a 2018 Global Hepatitis Summit conference abstract that was supported by MSD-Belgium and to which they provided some data. | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.rights | The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | - |
dc.subject.other | Disease elimination | - |
dc.subject.other | Health policy | - |
dc.subject.other | Hepatitis C | - |
dc.subject.other | Treatment | - |
dc.subject.other | Belgium | - |
dc.title | Eliminating viral hepatitis C in Belgium: the micro-elimination approach | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 20 | - |
local.format.pages | 12 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Lazarus, JV (reprint author), Univ Barcelona, Barcelona Inst Global Hlth ISGlobal, Hosp Clin, Barcelona, Spain. | - |
dc.description.notes | Jeffrey.lazarus@isglobal.org | - |
dc.description.other | Lazarus, JV (reprint author), Univ Barcelona, Barcelona Inst Global Hlth ISGlobal, Hosp Clin, Barcelona, Spain. Jeffrey.lazarus@isglobal.org | - |
local.publisher.place | CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 181 | - |
dc.source.type | Article | - |
dc.identifier.doi | 10.1186/s12879-020-4898-y | - |
dc.identifier.pmid | 32106819 | - |
dc.identifier.isi | WOS:000520583600003 | - |
dc.contributor.orcid | Lazarus, Jeffrey/0000-0001-9618-2299 | - |
dc.identifier.eissn | 1471-2334 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.uhasselt.international | yes | - |
item.validation | ecoom 2021 | - |
item.fulltext | With Fulltext | - |
item.fullcitation | BUSSCHOTS, Dana; Toghanian, Samira; BIELEN, Rob; Salomonsson, Stina; KOC, Ozgur; Hendrickx, Greet; Jadoul, Michel; Nevens, Frederik; Sokal, Etienne; Brixko, Christian; Peerlinck, Kathelijne; Apers, Ludwig; ROBAEYS, Geert & Lazarus, Jeffrey V. (2020) Eliminating viral hepatitis C in Belgium: the micro-elimination approach. In: BMC INFECTIOUS DISEASES, 20 (Art N° 181). | - |
item.accessRights | Open Access | - |
item.contributor | BUSSCHOTS, Dana | - |
item.contributor | Toghanian, Samira | - |
item.contributor | BIELEN, Rob | - |
item.contributor | Salomonsson, Stina | - |
item.contributor | KOC, Ozgur | - |
item.contributor | Hendrickx, Greet | - |
item.contributor | Jadoul, Michel | - |
item.contributor | Nevens, Frederik | - |
item.contributor | Sokal, Etienne | - |
item.contributor | Brixko, Christian | - |
item.contributor | Peerlinck, Kathelijne | - |
item.contributor | Apers, Ludwig | - |
item.contributor | ROBAEYS, Geert | - |
item.contributor | Lazarus, Jeffrey V. | - |
crisitem.journal.issn | 1471-2334 | - |
crisitem.journal.eissn | 1471-2334 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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dana.pdf | Published version | 655.23 kB | Adobe PDF | View/Open |
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