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http://hdl.handle.net/1942/31124
Title: | Climacturia: a comprehensive review assessing pathophysiology, prevalence, impact, and treatment options regarding the “leak of pleasure” | Authors: | Mykoniatis, Ioannis VAN RENTERGHEM, Koenraad Sokolakis, Ioannis Hatzichristodoulou, Georgios Sempels, Maxime Andrianne, Robert |
Issue Date: | 2021 | Publisher: | NATURE PUBLISHING GROUP | Source: | INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 33(3), p. 259-270 | Abstract: | Aim of this review is to summarize and evaluate the current literature on the pathophysiology, prevalence, sociosexual impact, and potential treatment options of climacturia. Climacturia, defined as orgasm-associated urinary incontinence and characterized by great prevalence variability, ranging between 15.7 and 93% was, so far, a relatively neglected post-radical prostatectomy functional side-effect. Recent studies have shown that it can significantly impact the quality of life of couples after prostate cancer treatment. A knowledge gap characterizes the pathophysiologic pathways while treatment is based on empirically chosen treatment options (condom use, presexual intercourse urination) or on therapeutic modalities proposed by low-quality studies (pelvic floor muscle training, penile applied devices). Evidence regarding efficacy of surgical techniques (artificial urinary sphincter, male sling, or dual implantation of penile prosthesis with a sling) for climacturia treatment are limited but with an increasing trend of relevant published data in the last 5 years. The mini-jupette sling plus inflatable penile prosthesis placement is a promising surgical technique that has been studied in a multi-institutional cohort with encouraging results regarding climacturia, erectile dysfunction, and mild-incontinence control. However, future studies with longer follow-up and larger sample sizes are certainly needed to confirm the long-term safety and benefits of this intervention. | Notes: | Mykoniatis, I (reprint author), Ctr Hosp Univ Liege, Serv dUrol, Hasselt, Belgium.; Mykoniatis, I (reprint author), Jessa Hosp, Dept Urol, Hasselt, Belgium. g_mikoniatis@hotmail.com |
Other: | Mykoniatis, I (reprint author), Ctr Hosp Univ Liege, Serv dUrol, Hasselt, Belgium; Jessa Hosp, Dept Urol, Hasselt, Belgium. g_mikoniatis@hotmail.com | Keywords: | Postradical Prostatectomy Incontinence;Sparing Radical Prostatectomy;Erectile Dysfunction;Urinary-Incontinence;Orgasmic Dysfunction;Predicting Factors;Radiation-Therapy;Cancer;Rehabilitation;Metaanalysis | Document URI: | http://hdl.handle.net/1942/31124 | ISSN: | 0955-9930 | e-ISSN: | 1476-5489 | DOI: | 10.1038/s41443-020-0257-1 | ISI #: | WOS:000520399400005 | Rights: | The Author(s), under exclusive licence to Springer Nature Limited 2020 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2021 |
Appears in Collections: | Research publications |
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