Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/3174
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | GEUSENS, Piet | - |
dc.contributor.author | Dequeker, J | - |
dc.contributor.author | VANHOOF, Johan | - |
dc.contributor.author | STALMANS, Rita | - |
dc.contributor.author | Boonen, S | - |
dc.contributor.author | Joly, J | - |
dc.contributor.author | Nijs, J | - |
dc.contributor.author | RAUS, Jef | - |
dc.date.accessioned | 2007-11-27T08:19:46Z | - |
dc.date.available | 2007-11-27T08:19:46Z | - |
dc.date.issued | 1998 | - |
dc.identifier.citation | ANNALS OF THE RHEUMATIC DISEASES, 57(12). p. 724-727 | - |
dc.identifier.issn | 0003-4967 | - |
dc.identifier.uri | http://hdl.handle.net/1942/3174 | - |
dc.description.abstract | Objective-To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. Methods-A double blind, randomised placebo controlled study comparing cyclic etidronate and placebo during two years in 37 postmenopausal women receiving long term corticosteroid treatment, mainly for polymyalgia rheumatica (40% of the patients) and rheumatoid arthritis (30%). Bone density was measured in the lumbar spine, femoral neck, and femoral trochanter. Results-After two years of treatment there was a significant difference between the groups in mean per cent change from baseline in bone density in the spine in favour of etidronate (p=0.003). The estimated treatment difference (mean (SD)) was 9.3 (2.1)%. Etidronate increased bone density in the spine (4.9 (2.1)%, p<0.05) whereas the placebo group lost bone (-2.4 (1.6)%). At the femoral neck there was an estimated difference of 5.3 (2.6)% between the groups (etidronate: 3.6 (1.4)%, p<0.05, placebo: -2.4 (2.1)%). The estimated difference at the trochanter was 8.2 (3.0) (etidronate: 9.0 (1.5)%, p<0.0001, placebo: 0.5 (2.3)%). No significant bone loss occurred in the hip in placebo treated patients. Conclusions-Cyclic etidronate is an effective treatment for postmenopausal women receiving corticosteroid treatment and is well tolerated. | - |
dc.language.iso | en | - |
dc.publisher | BRITISH MED JOURNAL PUBL GROUP | - |
dc.title | Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 727 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 724 | - |
dc.identifier.volume | 57 | - |
local.format.pages | 4 | - |
dc.description.notes | Limburgs Univ Ctr, Dr L Willems Inst, B-3590 Diepenbeek, Belgium. Akad Ziekenhuis Maastricht, Dept Rheumatol, Maastricht, Netherlands. KU Leuven, Arthrit & Metab Bone Dis Res Unit, Louvain, Belgium. KU Leuven, Dept Geriatr Med, Louvain, Belgium.Geusens, P, Limburgs Univ Ctr, Dr L Willems Inst, B-3590 Diepenbeek, Belgium. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.isi | 000077744800005 | - |
item.fullcitation | GEUSENS, Piet; Dequeker, J; VANHOOF, Johan; STALMANS, Rita; Boonen, S; Joly, J; Nijs, J & RAUS, Jef (1998) Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study. In: ANNALS OF THE RHEUMATIC DISEASES, 57(12). p. 724-727. | - |
item.validation | ecoom 2000 | - |
item.contributor | GEUSENS, Piet | - |
item.contributor | Dequeker, J | - |
item.contributor | VANHOOF, Johan | - |
item.contributor | STALMANS, Rita | - |
item.contributor | Boonen, S | - |
item.contributor | Joly, J | - |
item.contributor | Nijs, J | - |
item.contributor | RAUS, Jef | - |
item.fulltext | No Fulltext | - |
item.accessRights | Closed Access | - |
Appears in Collections: | Research publications |
WEB OF SCIENCETM
Citations
44
checked on May 10, 2024
Page view(s)
92
checked on Nov 1, 2023
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.