Viscerale leishmaniasis met hemofagocytaire lymfohistiocytose: casus en literatuuroverzicht

Abstract

Visceral leishmaniasis and hemophagocytic lymphohistiocytosis: a case report. The pathogenesis of haemophagocytic lymphohistiocytosis (HLH) secondary to an infection is based on an excessive, non-malignant proliferation of histiocytes leading to haemophagocytosis. HLH due to visceral leishmaniasis (VL) is a rare entity, certainly in non-endemic regio's like Belgium. The diagnosis remains often difficult. We present a case of fatal HLH caused by VL in an immunocompromised patient of 54 years.