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http://hdl.handle.net/1942/32447
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DC Field | Value | Language |
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dc.contributor.author | Perna, Eluisa | - |
dc.contributor.author | Aguilera-Lizarraga, Javier | - |
dc.contributor.author | Florens, Morgane V | - |
dc.contributor.author | Jain, Piyush | - |
dc.contributor.author | Theofanous, Stavroula A | - |
dc.contributor.author | Hanning, Nikita | - |
dc.contributor.author | De Man, Joris G | - |
dc.contributor.author | Berg, Maya | - |
dc.contributor.author | De Winter, Benedicte | - |
dc.contributor.author | AGUIAR ALPIZAR, Yeranddy | - |
dc.contributor.author | Talavera, Karel | - |
dc.contributor.author | Vanden Berghe, Pieter | - |
dc.contributor.author | Wouters, Mira | - |
dc.contributor.author | Boeckxstaens, Guy | - |
dc.date.accessioned | 2020-10-13T10:02:29Z | - |
dc.date.available | 2020-10-13T10:02:29Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2020-10-08T12:40:17Z | - |
dc.identifier.citation | Gut, 70 (7), p. 1275 - 1286 | - |
dc.identifier.issn | 0017-5749 | - |
dc.identifier.uri | http://hdl.handle.net/1942/32447 | - |
dc.description.abstract | Resolvins (RvD1, RvD2 and RvE1) are endogenous anti-inflammatory lipid mediators that display potent analgesic properties in somatic pain by modulating transient receptor potential vanilloid 1 (TRPV1) activation. To what extent these molecules could also have a beneficial effect on TRPV1 sensitisation and visceral hypersensitivity (VHS), mechanisms involved in IBS, remains unknown. | - |
dc.description.sponsorship | This work was supported by the Research Foundation—Flanders (FWO-SBO grant nr. S001017). MVF, MMW, PJ, JA-L and YAA were supported by an FWO doctoral or postdoctoral fellowship (1110017N/1110019N, 1248513N, 12R5219N, 12X9820N and 12H8217N). EP was supported by an Early Stage Researcher Marie Curie fellowship (NeuroGUT). We would like to thank the Cell and Tissue Imaging Cluster for the 470 use of the NIKON inverted TillVision 471 microscope, epifluorescence microscope BX 41 Olympus and Zeiss LSM880 – Airyscan 472 confocal microscope. Cell and Tissue Imaging Cluster, CIC, Supported by Hercules 473 AKUL/15/37_GOH1816N and FWO G.0929.15 to Prof. Pieter Vanden Berghe, KU Leuven. This work was supported by the Research Foundation - Flanders (FWO-SBO grant nr. S001017). MVF, MMW, PJ, JAL, and YAA were supported by an FWO doctoral or postdoctoral fellowship (1110017N/1110019N, 1248513N, 12R5219N, 12X9820N and 12H8217N). EP was supported by an Early Stage Researcher Marie Curie fellowship (NeuroGUT). | - |
dc.language.iso | en | - |
dc.publisher | BMJ PUBLISHING GROUP | - |
dc.rights | Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. | - |
dc.subject.other | ION channels | - |
dc.subject.other | abdominal pain | - |
dc.subject.other | irritable bowel syndrome | - |
dc.subject.other | neurogastroenterology | - |
dc.subject.other | visceral hypersensitivity | - |
dc.title | Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1286 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1275 | - |
dc.identifier.volume | 70 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1136/gutjnl-2020-321530 | - |
dc.identifier.pmid | 33023902 | - |
dc.identifier.isi | 000667248900010 | - |
dc.identifier.eissn | 1468-3288 | - |
local.provider.type | PubMed | - |
local.uhasselt.uhpub | yes | - |
local.uhasselt.international | no | - |
item.contributor | Perna, Eluisa | - |
item.contributor | Aguilera-Lizarraga, Javier | - |
item.contributor | Florens, Morgane V | - |
item.contributor | Jain, Piyush | - |
item.contributor | Theofanous, Stavroula A | - |
item.contributor | Hanning, Nikita | - |
item.contributor | De Man, Joris G | - |
item.contributor | Berg, Maya | - |
item.contributor | De Winter, Benedicte | - |
item.contributor | AGUIAR ALPIZAR, Yeranddy | - |
item.contributor | Talavera, Karel | - |
item.contributor | Vanden Berghe, Pieter | - |
item.contributor | Wouters, Mira | - |
item.contributor | Boeckxstaens, Guy | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.fullcitation | Perna, Eluisa; Aguilera-Lizarraga, Javier; Florens, Morgane V; Jain, Piyush; Theofanous, Stavroula A; Hanning, Nikita; De Man, Joris G; Berg, Maya; De Winter, Benedicte; AGUIAR ALPIZAR, Yeranddy; Talavera, Karel; Vanden Berghe, Pieter; Wouters, Mira & Boeckxstaens, Guy (2021) Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS. In: Gut, 70 (7), p. 1275 - 1286. | - |
item.validation | ecoom 2022 | - |
crisitem.journal.issn | 0017-5749 | - |
crisitem.journal.eissn | 1468-3288 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.pdf | Peer-reviewed author version | 1.17 MB | Adobe PDF | View/Open |
Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.pdf Restricted Access | Published version | 3.61 MB | Adobe PDF | View/Open Request a copy |
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