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http://hdl.handle.net/1942/32618
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DC Field | Value | Language |
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dc.contributor.author | Lafont, Alexandre | - |
dc.contributor.author | Sinnaeve, Peter R. | - |
dc.contributor.author | Cuisset, Thomas | - |
dc.contributor.author | Cook, Stephane | - |
dc.contributor.author | Sideris, Giorgios | - |
dc.contributor.author | Kedev, Sasko | - |
dc.contributor.author | Carrie, Didier | - |
dc.contributor.author | Hovasse, Thomas | - |
dc.contributor.author | Garot, Philippe | - |
dc.contributor.author | El Mahmoud, Rami | - |
dc.contributor.author | Spaulding, Christian | - |
dc.contributor.author | Helft, Gerard | - |
dc.contributor.author | Diaz Fernandez, Jose F. | - |
dc.contributor.author | Brugaleta, Salvatore | - |
dc.contributor.author | Pinar-Bermudez, Eduardo | - |
dc.contributor.author | Ferre, Josepa Mauri | - |
dc.contributor.author | Commeau, Philippe | - |
dc.contributor.author | Teiger, Emmanuel | - |
dc.contributor.author | BOGAERTS, Kris | - |
dc.contributor.author | Sabate, Manel | - |
dc.contributor.author | Morice, Marie Claude | - |
dc.contributor.author | Varenne, Olivier | - |
dc.date.accessioned | 2020-11-16T15:48:40Z | - |
dc.date.available | 2020-11-16T15:48:40Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2020-10-21T11:43:00Z | - |
dc.identifier.citation | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 97(5), p. E607-E613 | - |
dc.identifier.uri | http://hdl.handle.net/1942/32618 | - |
dc.description.abstract | Objectives Report the results at 2 years of the patients included in the SENIOR trial. Background Patients above 75 years of age represent a fast-growing population in the cathlab. In the SENIOR trial, patients treated by percutaneous coronary intervention (PCI) with drug eluting stent (DES) and a short duration of P2Y12 inhibitor (1 and 6 months for stable and unstable coronary syndromes, respectively) compared with bare metal stents (BMS) was associated with a 29% reduction in the rate of all-cause mortality, myocardial infarction (MI), stroke, and ischaemia-driven target lesion revascularization (ID-TLR) at 1 year. The results at 2 years are reported here. Methods and Results We randomly assigned 1,200 patients (596[50%] to the DES group and 604[50%] to the BMS group). At 2 years, the composite endpoint of all-cause mortality, MI, stroke and ID-TLR had occurred in 116 (20%) patients in the DES group and 131 (22%) patients in the BMS group (RR 0.90 [95%CI 0.72-1.13],p= .37). IDTLR occurred in 14 (2%) patients in the DES group and 41 (7%) patients in the BMS group (RR 0.35 [95%CI 0.16-0.60],p= .0002). Major bleedings (BARC 3-5) occurred in 27(5%) patients in both groups (RR 1.00, [95%CI 0.58-1.75],p= .99). Stent thrombosis rates were low and similar between DES and BMS (0.8 vs 1.3%, (RR 0.52 [95%CI 0.01-1.95],p= .27). Conclusion Among elderly PCI patients, a strategy combining a DES together with a short duration of DAPT is associated with a reduction in revascularization up to 2 years compared with BMS with very few late events and without any increased in bleeding complications or stent thrombosis. | - |
dc.description.sponsorship | Boston Scientific Corporation, Grant/Award Number: Through a grant to CERIC | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.rights | 2020 Wiley Periodicals LLC. | - |
dc.subject.other | bare metal stents | - |
dc.subject.other | drug eluting stents | - |
dc.subject.other | elderly patients | - |
dc.subject.other | PCI | - |
dc.subject.other | short DAPT | - |
dc.title | Two-year outcomes after percutaneous coronary intervention with drug-eluting stents or bare-metal stents in elderly patients with coronary artery disease | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | E613 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | E607 | - |
dc.identifier.volume | 97 | - |
local.format.pages | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Varenne, O (corresponding author), Hop Cochin, AP HP, F-75014 Paris, France. | - |
dc.description.notes | olivier.varenne@aphp.fr | - |
dc.description.other | Varenne, O (corresponding author), Hop Cochin, AP HP, F-75014 Paris, France. olivier.varenne@aphp.fr | - |
local.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1002/ccd.29159 | - |
dc.identifier.pmid | 32761890 | - |
dc.identifier.isi | WOS:000555892800001 | - |
dc.contributor.orcid | Kedev, Sasko/0000-0003-4844-6434 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Lafont, Alexandre; Varenne, Olivier] Hop Cochin, AP HP, Cardiol Dept, Paris, France. | - |
local.description.affiliation | [Lafont, Alexandre; Varenne, Olivier] Univ Paris, Paris, France. | - |
local.description.affiliation | [Sinnaeve, Peter R.] Univ Hosp Leuven, Dept Cardiovasc Med, Leuven, Belgium. | - |
local.description.affiliation | [Cuisset, Thomas] Ctr Hosp Univ Timone, Cardiol Dept, Marseille, France. | - |
local.description.affiliation | [Cook, Stephane] Univ & Hosp Fribourg, Cardiol Dept, Fribourg, Switzerland. | - |
local.description.affiliation | [Sideris, Giorgios] Univ Paris Diderot, Hop Lariboisiere, AP HP, Cardiol Dept,Serv Cardiol,Inst Natl Sante & Rech, Paris, France. | - |
local.description.affiliation | [Kedev, Sasko] Univ St Cyril & Methodius, Cardiol Dept, Skopje, North Macedonia. | - |
local.description.affiliation | [Carrie, Didier] Univ Paul Sabatier, Ctr Hosp Univ Toulouse Rangueil, Serv Cardiol, Toulouse, France. | - |
local.description.affiliation | [Hovasse, Thomas; Garot, Philippe] Ramsay Gen Sante, Inst Cardiovasc Paris Sud, Massy, France. | - |
local.description.affiliation | [El Mahmoud, Rami] Univ Versailles St Quentin Yvelines, Hop Ambroise Pare, AP HP, Versailles, France. | - |
local.description.affiliation | [Spaulding, Christian] Univ Paris, Hop Europeen Georges Pompidou, AP HP, Serv Cardiol, Paris, France. | - |
local.description.affiliation | [Spaulding, Christian] Inst Natl Sante & Rech Med U990, Sudden Death Expert Ctr, Paris, France. | - |
local.description.affiliation | [Helft, Gerard] Univ Paris 06, Hop Pitie Salpetriere, AP HP, Inst Cardiol, Paris, France. | - |
local.description.affiliation | [Helft, Gerard] Hop La Pitie Salpetriere, Inst Cardiometab & Nutr, Paris, France. | - |
local.description.affiliation | [Diaz Fernandez, Jose F.] Juan Ramon Jimenez Univ Hosp, Cardiol Dept, Huelva, Spain. | - |
local.description.affiliation | [Brugaleta, Salvatore] Inst Invest Biomed August Pi & Sunyer, Cardiovascular Inst, Hosp Clin, Barcelona, Spain. | - |
local.description.affiliation | [Pinar-Bermudez, Eduardo] Hosp Univ Virgen Arrixaca, Cardiol Dept, Murcia, Spain. | - |
local.description.affiliation | [Ferre, Josepa Mauri] Hosp Badalona Germans Trias & Pujol, Cardiol Dept, Badalona, Spain. | - |
local.description.affiliation | [Commeau, Philippe] Polyclin Les Fleurs, Dept Cardiol Intervent, Ollioules, France. | - |
local.description.affiliation | [Teiger, Emmanuel] Univ Paris Est Creteil, Hop Henri Mondor, AP HP, Serv Cardiol, Creteil, France. | - |
local.description.affiliation | [Bogaerts, Kris] Katholieke Univ Leuven, Interuniv Inst Biostat & Stat Bioinformat I Biost, Dept Publ Hlth & Primary Care, Leuven, Belgium. | - |
local.description.affiliation | [Bogaerts, Kris] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat I Biost, Hasselt, Belgium. | - |
local.description.affiliation | [Sabate, Manel] Inst Invest Biomed August Pi & Sunyer, Hosp Clin, Cardiovasc Inst, Intervent Cardiol Unit, Barcelona, Spain. | - |
local.description.affiliation | [Morice, Marie Claude] CERC Cardiovasc European Res Ctr, Massy, France. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Lafont, Alexandre; Sinnaeve, Peter R.; Cuisset, Thomas; Cook, Stephane; Sideris, Giorgios; Kedev, Sasko; Carrie, Didier; Hovasse, Thomas; Garot, Philippe; El Mahmoud, Rami; Spaulding, Christian; Helft, Gerard; Diaz Fernandez, Jose F.; Brugaleta, Salvatore; Pinar-Bermudez, Eduardo; Ferre, Josepa Mauri; Commeau, Philippe; Teiger, Emmanuel; BOGAERTS, Kris; Sabate, Manel; Morice, Marie Claude & Varenne, Olivier (2021) Two-year outcomes after percutaneous coronary intervention with drug-eluting stents or bare-metal stents in elderly patients with coronary artery disease. In: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 97(5), p. E607-E613. | - |
item.contributor | Lafont, Alexandre | - |
item.contributor | Sinnaeve, Peter R. | - |
item.contributor | Cuisset, Thomas | - |
item.contributor | Cook, Stephane | - |
item.contributor | Sideris, Giorgios | - |
item.contributor | Kedev, Sasko | - |
item.contributor | Carrie, Didier | - |
item.contributor | Hovasse, Thomas | - |
item.contributor | Garot, Philippe | - |
item.contributor | El Mahmoud, Rami | - |
item.contributor | Spaulding, Christian | - |
item.contributor | Helft, Gerard | - |
item.contributor | Diaz Fernandez, Jose F. | - |
item.contributor | Brugaleta, Salvatore | - |
item.contributor | Pinar-Bermudez, Eduardo | - |
item.contributor | Ferre, Josepa Mauri | - |
item.contributor | Commeau, Philippe | - |
item.contributor | Teiger, Emmanuel | - |
item.contributor | BOGAERTS, Kris | - |
item.contributor | Sabate, Manel | - |
item.contributor | Morice, Marie Claude | - |
item.contributor | Varenne, Olivier | - |
item.validation | ecoom 2021 | - |
item.accessRights | Restricted Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1522-1946 | - |
crisitem.journal.eissn | 1522-726X | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Cathet Cardio Intervent - 2020 - Lafont - Two‐year outcomes after percutaneous coronary intervention with drug‐eluting.pdf Restricted Access | Published version | 1.2 MB | Adobe PDF | View/Open Request a copy |
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