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http://hdl.handle.net/1942/32652
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DC Field | Value | Language |
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dc.contributor.author | Bislenghi, G. | - |
dc.contributor.author | Martin-Perez, B. | - |
dc.contributor.author | FIEUWS, Steffen | - |
dc.contributor.author | Wolthuis, A. | - |
dc.contributor.author | D'Hoore, A. | - |
dc.date.accessioned | 2020-11-23T10:03:48Z | - |
dc.date.available | 2020-11-23T10:03:48Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-11-03T14:11:47Z | - |
dc.identifier.citation | COLORECTAL DISEASE, | - |
dc.identifier.uri | http://hdl.handle.net/1942/32652 | - |
dc.description.abstract | Aim Ileal pouch-anal anastomosis (IPAA) should be delayed to a second stage in patients with ulcerative colitis and prolonged exposure to medical therapy. However, there is still discussion about whether a modified two-stage approach is preferable to a three-stage approach. Recently, a transanal approach has been introduced to overcome the well-known difficulties of laparoscopic pelvic surgery. This paper presents short-term outcomes of transanal IPAA (Ta-IPAA) according to a modified two-stage approach. Methods Data from all patients who underwent a modified two-stage Ta-IPAA for ulcerative colitis refractory to medical therapy were retrieved retrospectively from a prospective database. A comprehensive complication index was used for 90-day postoperative complications. Conversion, duration of surgery, hospital stay and reoperation were considered. A logistic regression model was used to assess risk factors for peri-pouch sepsis. Results Seventy-five (68.8%) patients were identified from 109 consecutive IPAAs. Median operation time was 159 min. Conversion rate was 4%. Mean comprehensive complication index was 7. All anastomotic leaks (10.6%) were treated with diverting ileostomy. Additionally, active rescue with transanal drainage and early resuturing of the anastomotic gap was performed in six patients. Ileostomy closure occurred after a median period of 5.4 months. At univariable analysis, factors associated with peri-pouch sepsis were male gender and age at IPAA construction. Conclusions A modified two-stage Ta-IPAA is safe and feasible. Standardization and reproducibility of the technique are reflected in few conversions and intra-operative complications. Finally, morbidity and anastomotic leak do not differ from those reported in previous Ta-IPAA series with a variable proportion of multistage procedures. | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.rights | ª 2020 The Association of Coloproctology of Great Britain and Ireland. | - |
dc.subject.other | Close rectal dissection | - |
dc.subject.other | ileal pouch anal anastomosis | - |
dc.subject.other | modified two-stage approach | - |
dc.subject.other | surgery | - |
dc.subject.other | transanal minimally invasive surgery | - |
dc.subject.other | ulcerative colitis | - |
dc.title | Increasing experience of modified two‐stage transanal ileal pouch–anal anastomosis for therapy refractory ulcerative colitis. What have we learned? A retrospective analysis on 75 consecutive cases at a tertiary referral hospital | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 83 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 74 | - |
dc.identifier.volume | 23 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bislenghi, G (corresponding author), Katholieke Univ Leuven, Univ Hosp Leuven, Dept Abdominal Surg, Herestr 49, B-3000 Leuven, Belgium. | - |
dc.description.notes | gabriele.bislenghi@uzleuven.be | - |
dc.description.other | Bislenghi, G (corresponding author), Katholieke Univ Leuven, Univ Hosp Leuven, Dept Abdominal Surg, Herestr 49, B-3000 Leuven, Belgium. gabriele.bislenghi@uzleuven.be | - |
local.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1111/codi.15231 | - |
dc.identifier.pmid | 32619321 | - |
dc.identifier.isi | WOS:000552879800001 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Bislenghi, G.; Martin-Perez, B.; Wolthuis, A.; D'Hoore, A.] Katholieke Univ Leuven, Univ Hosp Leuven, Dept Abdominal Surg, Herestr 49, B-3000 Leuven, Belgium. | - |
local.description.affiliation | [Fieuws, S.] Univ Leuven, Interuniv Ctr Biostat & Stat Bioinformat, Leuven, Belgium. | - |
local.description.affiliation | [Fieuws, S.] Univ Hasselt, Leuven, Belgium. | - |
item.accessRights | Restricted Access | - |
item.contributor | Bislenghi, G. | - |
item.contributor | Martin-Perez, B. | - |
item.contributor | FIEUWS, Steffen | - |
item.contributor | Wolthuis, A. | - |
item.contributor | D'Hoore, A. | - |
item.fullcitation | Bislenghi, G.; Martin-Perez, B.; FIEUWS, Steffen; Wolthuis, A. & D'Hoore, A. (2020) Increasing experience of modified two‐stage transanal ileal pouch–anal anastomosis for therapy refractory ulcerative colitis. What have we learned? A retrospective analysis on 75 consecutive cases at a tertiary referral hospital. In: COLORECTAL DISEASE,. | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2021 | - |
crisitem.journal.issn | 1462-8910 | - |
crisitem.journal.eissn | 1463-1318 | - |
Appears in Collections: | Research publications |
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Bislenghi_G_2020.pdf Restricted Access | Published version | 326.99 kB | Adobe PDF | View/Open Request a copy |
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