Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/32831
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dc.contributor.authorHo, Erwin-
dc.contributor.authorSCHENK, Julie-
dc.contributor.authorHutse, Veronik-
dc.contributor.authorSuin, Vanessa-
dc.contributor.authorLitzroth, Amber-
dc.contributor.authorBlaizot, Stephanie-
dc.contributor.authorHERZOG, Sereina-
dc.contributor.authorVerburgh, Vera-
dc.contributor.authorJacques, Marjorie-
dc.contributor.authorRahman, Abbas-
dc.contributor.authorMichielsen, Peter-
dc.contributor.authorVan Damme, Pierre-
dc.contributor.authorVan Gucht, Steven-
dc.contributor.authorTheeten, Heidi-
dc.contributor.authorHENS, Niel-
dc.contributor.authorVanwolleghem, Thomas-
dc.date.accessioned2020-12-09T13:09:24Z-
dc.date.available2020-12-09T13:09:24Z-
dc.date.issued2020-
dc.date.submitted2020-12-01T10:43:09Z-
dc.identifier.citationJournal of viral hepatitis (Print), 27 (11) , p. 1253 -1260-
dc.identifier.urihttp://hdl.handle.net/1942/32831-
dc.description.abstractRecent European studies suggest an emergence of hepatitis E virus (HEV) infection. We evaluated trends in birth cohort-specific HEV seroprevalence and regional differences in Belgium. HEV IgG seroprevalence was analysed on national serum banks (1579 and 2087 samples for 2006 and 2014, respectively. Hepatitis E virus antigen was tested on positive samples. Observed data were modelled using a generalized additive model with a complementary log-log link. No significant differences between birth cohorts or sexes were found. Modelling identified the individual's age and province as relevant factors. The probability of HEV seropositivity increases significantly with age. An estimated total of 434 819 (yearly rate of 54,352) (sero-)infections were found between 2006 and 2014. Overall, HEV IgG seroprevalences were 4.1% (64/1579, 95% CI 3.1-5.1) and 5.8% (121/2087, CI 4.8-6.9) in 2006 and 2014, respectively. Observed HEV antigen seroprevalence was 0.027% (1/3666) for the entire cohort. These results show stable HEV IgG seroprevalence in Belgium.-
dc.description.sponsorshipGilead SciencesGilead Sciences [Gilead Sciences BeLux Fellowship 2017] Funding Source: Medline; European Union Horizon 2020 research and innovation [682540 - TransMID] Funding Source: Medline; Foundation Against Cancer Belgium [2014-087] Funding Source: Medline-
dc.language.isoen-
dc.publisherWILEY-
dc.subject.otherBelgium-
dc.subject.otherepidemiology-
dc.subject.otherEurope-
dc.subject.otherhepatitis E-
dc.titleStable HEV IgG seroprevalence in Belgium between 2006 and 2014-
dc.typeJournal Contribution-
dc.identifier.epage1260-
dc.identifier.issue11-
dc.identifier.spage1253-
dc.identifier.volume27-
local.format.pages8-
local.bibliographicCitation.jcatA1-
dc.description.notesVanwolleghem, T (corresponding author), Antwerp Univ Hosp, Dept Gastroenterol & Hepatol, Edegem, Belgium.-
dc.description.notesthomas.vanwolleghem@uza.be-
dc.description.otherVanwolleghem, T (corresponding author), Antwerp Univ Hosp, Dept Gastroenterol & Hepatol, Edegem, Belgium. thomas.vanwolleghem@uza.be-
local.publisher.place111 RIVER ST, HOBOKEN 07030-5774, NJ USA-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.type.programmeH2020-
local.relation.h2020682540-
dc.identifier.doi10.1111/jvh.13347-
dc.identifier.isiWOS:000575345200016-
dc.contributor.orcidvan damme, pierre/0000-0002-8642-1249-
dc.identifier.eissn-
dc.identifier.eissn1365-2893-
local.provider.typewosris-
local.uhasselt.uhpubyes-
local.description.affiliation[Ho, Erwin; Michielsen, Peter; Vanwolleghem, Thomas] Antwerp Univ Hosp, Dept Gastroenterol & Hepatol, Edegem, Belgium.-
local.description.affiliation[Ho, Erwin; Michielsen, Peter; Vanwolleghem, Thomas] Univ Antwerp, Lab Expt Med & Paediat, Fac Med & Hlth Sci, Antwerp, Belgium.-
local.description.affiliation[Schenk, Julie; Hens, Niel] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Data Sci Inst, Hasselt, Belgium.-
local.description.affiliation[Schenk, Julie; Blaizot, Stephanie; Herzog, Sereina A.; Hens, Niel] Univ Antwerp, Vaccine & Infect Dis Inst, Ctr Hlth Econ Res & Modelling Infect Dis, Fac Med & Hlth Sci, Antwerp, Belgium.-
local.description.affiliation[Hutse, Veronik; Suin, Vanessa; Verburgh, Vera; Jacques, Marjorie] Natl Reference Ctr Hepatitis Viruses, Sci Directorate Infect Dis Humans, Sciensano, Belgium.-
local.description.affiliation[Litzroth, Amber] Sci Directorate Epidemiol & Publ Hlth, Sciensano, Belgium.-
local.description.affiliation[Rahman, Abbas; Van Damme, Pierre; Theeten, Heidi] Univ Antwerp, Fac Med & Hlth Sci, Vaccine & Infect Dis Inst, Ctr Evaluat Vaccinat, Antwerp, Belgium.-
local.uhasselt.internationalno-
item.contributorHo, Erwin-
item.contributorSCHENK, Julie-
item.contributorHutse, Veronik-
item.contributorSuin, Vanessa-
item.contributorLitzroth, Amber-
item.contributorBlaizot, Stephanie-
item.contributorHERZOG, Sereina-
item.contributorVerburgh, Vera-
item.contributorJacques, Marjorie-
item.contributorRahman, Abbas-
item.contributorMichielsen, Peter-
item.contributorVan Damme, Pierre-
item.contributorVan Gucht, Steven-
item.contributorTheeten, Heidi-
item.contributorHENS, Niel-
item.contributorVanwolleghem, Thomas-
item.fullcitationHo, Erwin; SCHENK, Julie; Hutse, Veronik; Suin, Vanessa; Litzroth, Amber; Blaizot, Stephanie; HERZOG, Sereina; Verburgh, Vera; Jacques, Marjorie; Rahman, Abbas; Michielsen, Peter; Van Damme, Pierre; Van Gucht, Steven; Theeten, Heidi; HENS, Niel & Vanwolleghem, Thomas (2020) Stable HEV IgG seroprevalence in Belgium between 2006 and 2014. In: Journal of viral hepatitis (Print), 27 (11) , p. 1253 -1260.-
item.accessRightsOpen Access-
item.fulltextWith Fulltext-
item.validationecoom 2021-
crisitem.journal.issn1352-0504-
crisitem.journal.eissn1365-2893-
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