Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/3283
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DC Field | Value | Language |
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dc.contributor.author | MEDAER, Rob | - |
dc.contributor.author | STINISSEN, Piet | - |
dc.contributor.author | ZHANG, JINGWU | - |
dc.contributor.author | RAUS, Jef | - |
dc.date.accessioned | 2007-11-27T13:26:17Z | - |
dc.date.available | 2007-11-27T13:26:17Z | - |
dc.date.issued | 1997 | - |
dc.identifier.citation | BIODRUGS, 8(1). p. 1-5 | - |
dc.identifier.issn | 1173-8804 | - |
dc.identifier.uri | http://hdl.handle.net/1942/3283 | - |
dc.description.abstract | Accumulating evidence indicates that multiple sclerosis, a chronic inflammatory disease of the central nervous system, has an autoimmune origin. Since T cells reactive to myelin basic protein (MBP) are thought to play an important role in the pathogenesis of this disease, it was assumed that inactivation or depletion of this pathogenic T cell subset may have therapeutic effects in multiple sclerosis. We have recently reported that T cell vaccination, i.e. immunisation with attenuated autologous MBP-reactive T cell clones, leads to the depletion of the MBP-reactive T cells. Furthermore, this approach induced favourable clinical effects in the treated patients, encouraging further studies of T cell vaccination in multiple sclerosis. | - |
dc.language.iso | en | - |
dc.publisher | ADIS INTERNATIONAL LTD | - |
dc.title | Prospects for T cell vaccination in multiple sclerosis | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 5 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 1 | - |
dc.identifier.volume | 8 | - |
local.format.pages | 5 | - |
dc.description.notes | LIMBURGS UNIV CTR,DIEPENBEEK,BELGIUM.Medaer, R, DR L WILLEMS INST,UNIV CAMPUS,B-3590 DIEPENBEEK,BELGIUM. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.isi | A1997XJ48500001 | - |
item.fulltext | No Fulltext | - |
item.fullcitation | MEDAER, Rob; STINISSEN, Piet; ZHANG, JINGWU & RAUS, Jef (1997) Prospects for T cell vaccination in multiple sclerosis. In: BIODRUGS, 8(1). p. 1-5. | - |
item.accessRights | Closed Access | - |
item.contributor | MEDAER, Rob | - |
item.contributor | STINISSEN, Piet | - |
item.contributor | ZHANG, JINGWU | - |
item.contributor | RAUS, Jef | - |
Appears in Collections: | Research publications |
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