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http://hdl.handle.net/1942/32936
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DC Field | Value | Language |
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dc.contributor.author | Moller, Peter | - |
dc.contributor.author | Azqueta, Amaya | - |
dc.contributor.author | Boutet-Robinet, Elisa | - |
dc.contributor.author | Koppen, Gudrun | - |
dc.contributor.author | Bonassi, Stefano | - |
dc.contributor.author | Milic, Mirta | - |
dc.contributor.author | Gajski, Goran | - |
dc.contributor.author | Costa, Solange | - |
dc.contributor.author | Teixeira, Joao Paulo | - |
dc.contributor.author | Costa Pereira, Cristiana | - |
dc.contributor.author | Dusinska, Maria | - |
dc.contributor.author | GODSCHALK, Roger | - |
dc.contributor.author | Brunborg, Gunnar | - |
dc.contributor.author | Gutzkow, Kristine B. | - |
dc.contributor.author | Giovannelli, Lisa | - |
dc.contributor.author | Cooke, Marcus S. | - |
dc.contributor.author | Richling, Elke | - |
dc.contributor.author | Laffon, Blanca | - |
dc.contributor.author | Valdiglesias, Vanessa | - |
dc.contributor.author | Basaran, Nursen | - |
dc.contributor.author | Del Bo', Cristian | - |
dc.contributor.author | Zegura, Bojana | - |
dc.contributor.author | Novak, Matjaz | - |
dc.contributor.author | Stopper, Helga | - |
dc.contributor.author | Vodicka, Pavel | - |
dc.contributor.author | Vodenkova, Sona | - |
dc.contributor.author | de Andrade, Vanessa Moraes | - |
dc.contributor.author | Sramkova, Monika | - |
dc.contributor.author | Gabelova, Alena | - |
dc.contributor.author | Collins, Andrew | - |
dc.contributor.author | LANGIE, Sabine | - |
dc.date.accessioned | 2020-12-15T12:28:49Z | - |
dc.date.available | 2020-12-15T12:28:49Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-12-15T11:03:45Z | - |
dc.identifier.citation | Nature Protocols, 15 (12) , p. 3817 -3826 | - |
dc.identifier.uri | http://hdl.handle.net/1942/32936 | - |
dc.description.abstract | The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. These differences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because detailed comet assay procedures are not always published. Here, we present a Consensus Statement for the Minimum Information for Reporting Comet Assay (MIRCA) providing recommendations for describing comet assay conditions and results. These recommendations differentiate between 'desirable' and 'essential' information: 'essential' information refers to the precise details that are necessary to assess the quality of the experimental work, whereas 'desirable' information relates to technical issues that might be encountered when repeating the experiments. Adherence to MIRCA recommendations should ensure that comet assay results can be easily interpreted and independently verified by other researchers. Here, members of the hCOMET COST Action program provide a consensus statement on the Minimum Information for Reporting Comet Assays (MIRCA). | - |
dc.language.iso | en | - |
dc.publisher | NATURE RESEARCH | - |
dc.rights | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | - |
dc.title | Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 3826 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 3817 | - |
dc.identifier.volume | 15 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Moller, P (corresponding author), Univ Copenhagen, Sect Environm Hlth, Dept Publ Hlth, Copenhagen, Denmark. | - |
dc.description.notes | pemo@sund.ku.dk | - |
dc.description.other | Moller, P (corresponding author), Univ Copenhagen, Sect Environm Hlth, Dept Publ Hlth, Copenhagen, Denmark. pemo@sund.ku.dk | - |
local.publisher.place | HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1038/s41596-020-0398-1 | - |
dc.identifier.isi | WOS:000583953500001 | - |
dc.contributor.orcid | Azqueta, Amaya/0000-0003-4857-9931; Pereira, | - |
dc.contributor.orcid | Cristiana/0000-0002-2146-1223; bonassi, stefano/0000-0003-3833-6717; | - |
dc.contributor.orcid | Boutet-Robinet, Elisa/0000-0002-5223-4568; Paulo Teixeira, | - |
dc.contributor.orcid | Joao/0000-0001-8693-5250 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Moller, Peter] Univ Copenhagen, Sect Environm Hlth, Dept Publ Hlth, Copenhagen, Denmark. | - |
local.description.affiliation | [Azqueta, Amaya] Univ Navarra, Dept Pharmacol & Toxicol, Pamplona, Spain. | - |
local.description.affiliation | [Azqueta, Amaya] Navarra Inst Hlth Res, IdiSNA, Pamplona, Spain. | - |
local.description.affiliation | [Boutet-Robinet, Elisa] Univ Toulouse, INRAE, ENVT, Toxalim Res Ctr Food Toxicol,INP Purpan,UPS, Toulouse, France. | - |
local.description.affiliation | [Koppen, Gudrun] VITO Hlth, Mol, Belgium. | - |
local.description.affiliation | [Bonassi, Stefano] IRCCS San Raffaele Pisana, Unit Clin & Mol Epidemiol, Rome, Italy. | - |
local.description.affiliation | [Bonassi, Stefano] San Raffaele Univ, Dept Human Sci & Qual Life Promot, Rome, Italy. | - |
local.description.affiliation | [Milic, Mirta; Gajski, Goran] Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia. | - |
local.description.affiliation | [Costa, Solange; Teixeira, Joao Paulo; Costa Pereira, Cristiana] Natl Inst Hlth Dr Ricardo Jorge, Environm Hlth Dept, Porto, Portugal. | - |
local.description.affiliation | [Costa, Solange; Teixeira, Joao Paulo; Costa Pereira, Cristiana] Univ Porto, Inst Saude Publ, Epidemiol Res Unit EPIUnit, Porto, Portugal. | - |
local.description.affiliation | [Dusinska, Maria] Norwegian Inst Air Res NILU, Dept Environm Chem, Hlth Effects Lab, Kjeller, Norway. | - |
local.description.affiliation | [Godschalk, Roger; Langie, Sabine A. S.] Maastricht Univ, Sch Nutr & Translat Res Metab NUTRIM, Dept Pharmacol & Toxicol, Maastricht, Netherlands. | - |
local.description.affiliation | [Brunborg, Gunnar; Gutzkow, Kristine B.] Norwegian Inst Publ Hlth Skoyen, Dept Environm Hlth, Sect Mol Toxicol, Oslo, Norway. | - |
local.description.affiliation | [Giovannelli, Lisa] Univ Florence, Sect Pharmacol & Toxicol, Dept Neurosci Psychol Pharmacol & Child Hlth NEUR, Florence, Italy. | - |
local.description.affiliation | [Cooke, Marcus S.] Univ S Florida, Dept Cell Biol Microbiol & Mol Biol, Oxidat Stress Grp, Tampa, FL 33620 USA. | - |
local.description.affiliation | [Richling, Elke] Univ Kaiserslautern, Dept Chem, Food Chem & Toxicol, Kaiserslautern, Germany. | - |
local.description.affiliation | [Laffon, Blanca; Valdiglesias, Vanessa] Univ A Coruna, Fac Ciencias Educ, Dept Psicol, Ctr Invest Cient Avanzadas CICA,Grp DICOMOSA, Coruna, Spain. | - |
local.description.affiliation | [Laffon, Blanca; Valdiglesias, Vanessa] AE CICA INIBIC, Inst Invest Biomed A Coruna INIBIC, Coruna, Spain. | - |
local.description.affiliation | [Basaran, Nursen] Hacettepe Univ, Dept Toxicol, Fac Pharm, Ankara, Turkey. | - |
local.description.affiliation | [Del Bo', Cristian] Univ Milan, Dept Food Environm & Nutr Sci DeFENS, Div Human Nutr, Milan, Italy. | - |
local.description.affiliation | [Zegura, Bojana; Novak, Matjaz] Natl Inst Biol, Dept Genet Toxicol & Canc Biol, Ljubljana, Slovenia. | - |
local.description.affiliation | [Stopper, Helga] Univ Wurzburg, Inst Pharmacol & Toxicol, Wurzburg, Germany. | - |
local.description.affiliation | [Vodicka, Pavel; Vodenkova, Sona] Czech Acad Sci, Inst Expt Med, Prague, Czech Republic. | - |
local.description.affiliation | [Vodicka, Pavel; Vodenkova, Sona] Charles Univ Prague, Med Fac Pilsen, Biomed Ctr, Prague, Czech Republic. | - |
local.description.affiliation | [de Andrade, Vanessa Moraes] Univ Southern Santa Catarina, Lab Translat Biomed, UNESC, Criciuma, SC, Brazil. | - |
local.description.affiliation | [Sramkova, Monika; Gabelova, Alena] Slovak Acad Sci, Biomed Res Ctr, Canc Res Inst, Dept Nanobiol, Bratislava, Slovakia. | - |
local.description.affiliation | [Collins, Andrew] Univ Oslo, Dept Nutr, Oslo, Norway. | - |
local.description.affiliation | [Langie, Sabine A. S.] Hasselt Univ, Ctr Environm Sci, Hasselt, Belgium. | - |
local.uhasselt.international | yes | - |
item.validation | ecoom 2021 | - |
item.fullcitation | Moller, Peter; Azqueta, Amaya; Boutet-Robinet, Elisa; Koppen, Gudrun; Bonassi, Stefano; Milic, Mirta; Gajski, Goran; Costa, Solange; Teixeira, Joao Paulo; Costa Pereira, Cristiana; Dusinska, Maria; GODSCHALK, Roger; Brunborg, Gunnar; Gutzkow, Kristine B.; Giovannelli, Lisa; Cooke, Marcus S.; Richling, Elke; Laffon, Blanca; Valdiglesias, Vanessa; Basaran, Nursen; Del Bo', Cristian; Zegura, Bojana; Novak, Matjaz; Stopper, Helga; Vodicka, Pavel; Vodenkova, Sona; de Andrade, Vanessa Moraes; Sramkova, Monika; Gabelova, Alena; Collins, Andrew & LANGIE, Sabine (2020) Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. In: Nature Protocols, 15 (12) , p. 3817 -3826. | - |
item.contributor | Moller, Peter | - |
item.contributor | Azqueta, Amaya | - |
item.contributor | Boutet-Robinet, Elisa | - |
item.contributor | Koppen, Gudrun | - |
item.contributor | Bonassi, Stefano | - |
item.contributor | Milic, Mirta | - |
item.contributor | Gajski, Goran | - |
item.contributor | Costa, Solange | - |
item.contributor | Teixeira, Joao Paulo | - |
item.contributor | Costa Pereira, Cristiana | - |
item.contributor | Dusinska, Maria | - |
item.contributor | GODSCHALK, Roger | - |
item.contributor | Brunborg, Gunnar | - |
item.contributor | Gutzkow, Kristine B. | - |
item.contributor | Giovannelli, Lisa | - |
item.contributor | Cooke, Marcus S. | - |
item.contributor | Richling, Elke | - |
item.contributor | Laffon, Blanca | - |
item.contributor | Valdiglesias, Vanessa | - |
item.contributor | Basaran, Nursen | - |
item.contributor | Del Bo', Cristian | - |
item.contributor | Zegura, Bojana | - |
item.contributor | Novak, Matjaz | - |
item.contributor | Stopper, Helga | - |
item.contributor | Vodicka, Pavel | - |
item.contributor | Vodenkova, Sona | - |
item.contributor | de Andrade, Vanessa Moraes | - |
item.contributor | Sramkova, Monika | - |
item.contributor | Gabelova, Alena | - |
item.contributor | Collins, Andrew | - |
item.contributor | LANGIE, Sabine | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1754-2189 | - |
crisitem.journal.eissn | 1750-2799 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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s41596-020-0398-1.pdf | Published version | 935.35 kB | Adobe PDF | View/Open |
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