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http://hdl.handle.net/1942/32939
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DC Field | Value | Language |
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dc.contributor.author | BOER, Willem | - |
dc.contributor.author | van Tornout, Mathias | - |
dc.contributor.author | SOLMI, Francesca | - |
dc.contributor.author | Willaert, Xavier | - |
dc.contributor.author | Schetz, Miet | - |
dc.contributor.author | Oudemans-van Straaten, Heleen | - |
dc.date.accessioned | 2020-12-15T13:50:36Z | - |
dc.date.available | 2020-12-15T13:50:36Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-12-15T10:47:16Z | - |
dc.identifier.citation | JOURNAL OF CRITICAL CARE, 59 , p. 16 -22 | - |
dc.identifier.uri | http://hdl.handle.net/1942/32939 | - |
dc.description.abstract | Purpose: To identify potential determinants of the Total/ionized Ca ratio (T/iCa), a marker of citrate acctimulation. Materials and methods: Single-center retrospective observational study evaluating citrate dose, citrate target, albumin, phosphate, pH, lactate, and APACHE II score as potential determinants. Linear mixed models (LMM) using citrate dose and citrate target were developed describing associations with T/iCa. Results: From a dataset of 471 samples in 103 patients, an LMM in 379 complete samples (95 patients) sets revealed that citrate dose, pH, phosphate, albumin and APACHE were interactively related to T/iCa. A rising citrate dose was associated with a higher increase in T/iCa when phosphate was high, and less when phosphate was low. A rising albumin was associated with a higher increase in T/iCa when APACHE was high and phosphate was low and less when APACHE was low and phosphate high. In case of acidosis, a rising lactate was associated with a higher increase in T/iCa. In the LMM using citrate target, citrate target and pH were the main independent predictors of T/iCa with albumin, phosphate and APACHE score as modifiers. Conclusions: Besides citrate dose, a high pH and high phosphate, albumin and APACHE are also associated with a rising T/iCa. (C) 2020 Elsevier Inc. All rights reserved. | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | - |
dc.subject.other | AKI | - |
dc.subject.other | CVVH | - |
dc.subject.other | Regional citrate anticoagulation | - |
dc.subject.other | Citrate accumulation | - |
dc.subject.other | Calcium ratio | - |
dc.title | Determinants of Total/ionized Calcium in patients undergoing citrate CVVH: A retrospective observational study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 22 | - |
dc.identifier.spage | 16 | - |
dc.identifier.volume | 59 | - |
local.format.pages | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Boer, W (corresponding author), Ziekenhuis Oost Limburg ZOL, Dept Anesthesiol Intens Care Med Emergency Med &, Schiepsehos 6, B-3600 Genk, Belgium. | - |
dc.description.notes | willem.boer@zol.be | - |
dc.description.other | Boer, W (corresponding author), Ziekenhuis Oost Limburg ZOL, Dept Anesthesiol Intens Care Med Emergency Med &, Schiepsehos 6, B-3600 Genk, Belgium. willem.boer@zol.be | - |
local.publisher.place | 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.jcrc.2020.05.005 | - |
dc.identifier.isi | WOS:000581019400003 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Boer, Willem; van Tornout, Mathias; Willaert, Xavier] Ziekenhuis Oost Limburg ZOL, Dept Anesthesiol Intens Care Med Emergency Med &, Schiepsehos 6, B-3600 Genk, Belgium. | - |
local.description.affiliation | [Schetz, Miet] Katholieke Univ Leuven, Dept Lab & Intens Care Med, Leuven, Belgium. | - |
local.description.affiliation | [Solmi, Francesca] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Data Sci Inst, Hasselt, Belgium. | - |
local.description.affiliation | [Oudemans-van Straaten, Heleen] Univ Amsterdam, Med Ctr, Locat VUmc, Amsterdam, Netherlands. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2021 | - |
item.contributor | BOER, Willem | - |
item.contributor | van Tornout, Mathias | - |
item.contributor | SOLMI, Francesca | - |
item.contributor | Willaert, Xavier | - |
item.contributor | Schetz, Miet | - |
item.contributor | Oudemans-van Straaten, Heleen | - |
item.fullcitation | BOER, Willem; van Tornout, Mathias; SOLMI, Francesca; Willaert, Xavier; Schetz, Miet & Oudemans-van Straaten, Heleen (2020) Determinants of Total/ionized Calcium in patients undergoing citrate CVVH: A retrospective observational study. In: JOURNAL OF CRITICAL CARE, 59 , p. 16 -22. | - |
crisitem.journal.issn | 0883-9441 | - |
crisitem.journal.eissn | 1557-8615 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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1-s2.0-S088394412030561X-main.pdf Restricted Access | Published version | 1.09 MB | Adobe PDF | View/Open Request a copy |
OA_post_JCC_May_2020_Schetz.pdf | Peer-reviewed author version | 350.93 kB | Adobe PDF | View/Open |
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