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http://hdl.handle.net/1942/33113
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DC Field | Value | Language |
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dc.contributor.author | EVENS, Lize | - |
dc.contributor.author | BELIEN, Hanne | - |
dc.contributor.author | DELUYKER, Dorien | - |
dc.contributor.author | BRONCKAERS, Annelies | - |
dc.contributor.author | GERVOIS, Pascal | - |
dc.contributor.author | HENDRIKX, Marc | - |
dc.contributor.author | BITO, Virginie | - |
dc.date.accessioned | 2021-01-19T09:29:00Z | - |
dc.date.available | 2021-01-19T09:29:00Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2021-01-13T14:06:32Z | - |
dc.identifier.citation | Stem Cells International, 2020 (Art N° 8886612) | - |
dc.identifier.uri | http://hdl.handle.net/1942/33113 | - |
dc.description.abstract | Stem cell-based regenerative therapies hold great promises to treat a wide spectrum of diseases. However, stem cell engraftment and survival are still challenging due to an unfavorable transplantation environment. Advanced glycation end-products (AGEs) can contribute to the generation of these harmful conditions. AGEs are a heterogeneous group of glycated products, nonenzymatically formed when proteins and/or lipids become glycated and oxidized. Our typical Western diet as well as cigarettes contain high AGEs content. AGEs are also endogenously formed in our body and accumulate with senescence and in pathological situations. Whether AGEs have an impact on stem cell viability in regenerative medicine remains unclear, and research on the effect of AGEs on stem cell proliferation and apoptosis is still ongoing. Therefore, this systematic review provides a clear overview of the effects of glycated proteins on cell viability in various types of primary isolated stem cells used in regenerative medicine. | - |
dc.description.sponsorship | Figures were created using images from Servier Medical Art Commons Attribution 3.0 Unported License (http://smart.servier.com). Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License. This work was supported by a Bijzonder onderzoeksfonds (BOF) grant from Hasselt University (grant number: 16NI05BOF). HB benefits from an aspirant PhD mandate (grant number: 1154120N) of the `Research Foundation-Flanders' (fonds voor wetenschappelijk onderzoek (FWO)). PG is also supported by the FWO (grant numbers: 12U7718N and 1502120N). | - |
dc.language.iso | en | - |
dc.publisher | HINDAWI LTD | - |
dc.rights | Copyright © 2020 Lize Evens et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | - |
dc.title | The Impact of Advanced Glycation End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 2020 | - |
local.format.pages | 13 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bito, V (corresponding author), Hasselt Univ, Biomed BIOMED Res Inst, Agoralaan Bldg C, B-3590 Diepenbeek, Belgium. | - |
dc.description.notes | virginie.bito@uhasselt.be | - |
dc.description.other | Bito, V (corresponding author), Hasselt Univ, Biomed BIOMED Res Inst, Agoralaan Bldg C, B-3590 Diepenbeek, Belgium. virginie.bito@uhasselt.be | - |
local.publisher.place | ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
local.bibliographicCitation.artnr | 8886612 | - |
dc.identifier.doi | 10.1155/2020/8886612 | - |
dc.identifier.isi | WOS:000597357900002 | - |
dc.contributor.orcid | Bronckaers, Annelies/0000-0001-8969-873X | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Evens, Lize; Belien, Hanne; Deluyker, Dorien; Bronckaers, Annelies; Gervois, Pascal; Bito, Virginie] Hasselt Univ, Biomed BIOMED Res Inst, Agoralaan Bldg C, B-3590 Diepenbeek, Belgium. | - |
local.description.affiliation | [Hendrikx, Marc] Hasselt Univ, Fac Med & Life Sci, Martelarenlaan 42, B-3500 Hasselt, Belgium. | - |
local.uhasselt.international | no | - |
item.contributor | EVENS, Lize | - |
item.contributor | BELIEN, Hanne | - |
item.contributor | DELUYKER, Dorien | - |
item.contributor | BRONCKAERS, Annelies | - |
item.contributor | GERVOIS, Pascal | - |
item.contributor | HENDRIKX, Marc | - |
item.contributor | BITO, Virginie | - |
item.validation | ecoom 2021 | - |
item.fullcitation | EVENS, Lize; BELIEN, Hanne; DELUYKER, Dorien; BRONCKAERS, Annelies; GERVOIS, Pascal; HENDRIKX, Marc & BITO, Virginie (2020) The Impact of Advanced Glycation End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review. In: Stem Cells International, 2020 (Art N° 8886612). | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1687-966X | - |
crisitem.journal.eissn | 1687-9678 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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8886612.pdf | Published version | 895.13 kB | Adobe PDF | View/Open |
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