Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/33122
Title: Nanoscale Dynamic Readout of a Chemical Redox Process Using Radicals Coupled with Nitrogen-Vacancy Centers in Nanodiamonds
Authors: Barton, Jan
GULKA, Michal 
Tarabek, Jan
Mindarava, Yuliya
Wang, Zhenyu
Schimer, Jiri
Raabova, Helena
Bednar, Jan
Plenio, Martin B.
Jelezko, Fedor
NESLADEK, Milos 
Cigler, Petr
Issue Date: 2020
Publisher: AMER CHEMICAL SOC
Source: ACS Nano, 14 (10) , p. 12938 -12950
Abstract: Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chernical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we describe an analytical tool based on quantum sensing techniques. We magnetically coupled negatively charged nitrogen-vacancy (NV) centers in ranodiamonds (NDs) with nitroxide radicals present in a biomert polymer coating of the NDs. We demonstrated that the T-1 spin relaxation time of the NV centers is very sensitive to the number of nitroxide radicals, with a resolution down to 10 spins per ND (detection of approximately 10-23 mol in a localized volume). The detection is based on T-1 shortening upon the radical attachment, and we propose a theoretical m odel describing this phenomenon. We further show that this colloidally stable, water-soluble system can be used dynamically for spatiotemporal readout of a redox chemical process (oxidation of ascorbic acid) occurring near the ND surface in an aqueous environment under ambient conditions.
Notes: Cigler, P (corresponding author), Czech Acad Sci, Inst Organ Chem & Biochem, Prague 16610, Czech Republic.
cigler@uochb.cas.cz
Other: Cigler, P (corresponding author), Czech Acad Sci, Inst Organ Chem & Biochem, Prague 16610, Czech Republic. cigler@uochb.cas.cz
Keywords: quantum sensing;nanodiamond;nitrogen-vacancy center;radical;chemical reaction;T-1 spin relaxation time
Document URI: http://hdl.handle.net/1942/33122
ISSN: 1936-0851
e-ISSN: 1936-086X
DOI: 10.1021/acsnano.0c04010
ISI #: WOS:000586793400049
Category: A1
Type: Journal Contribution
Validations: ecoom 2021
Appears in Collections:Research publications

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