Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/33122
Title: | Nanoscale Dynamic Readout of a Chemical Redox Process Using Radicals Coupled with Nitrogen-Vacancy Centers in Nanodiamonds | Authors: | Barton, Jan GULKA, Michal Tarabek, Jan Mindarava, Yuliya Wang, Zhenyu Schimer, Jiri Raabova, Helena Bednar, Jan Plenio, Martin B. Jelezko, Fedor NESLADEK, Milos Cigler, Petr |
Issue Date: | 2020 | Publisher: | AMER CHEMICAL SOC | Source: | ACS Nano, 14 (10) , p. 12938 -12950 | Abstract: | Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chernical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we describe an analytical tool based on quantum sensing techniques. We magnetically coupled negatively charged nitrogen-vacancy (NV) centers in ranodiamonds (NDs) with nitroxide radicals present in a biomert polymer coating of the NDs. We demonstrated that the T-1 spin relaxation time of the NV centers is very sensitive to the number of nitroxide radicals, with a resolution down to 10 spins per ND (detection of approximately 10-23 mol in a localized volume). The detection is based on T-1 shortening upon the radical attachment, and we propose a theoretical m odel describing this phenomenon. We further show that this colloidally stable, water-soluble system can be used dynamically for spatiotemporal readout of a redox chemical process (oxidation of ascorbic acid) occurring near the ND surface in an aqueous environment under ambient conditions. | Notes: | Cigler, P (corresponding author), Czech Acad Sci, Inst Organ Chem & Biochem, Prague 16610, Czech Republic. cigler@uochb.cas.cz |
Other: | Cigler, P (corresponding author), Czech Acad Sci, Inst Organ Chem & Biochem, Prague 16610, Czech Republic. cigler@uochb.cas.cz | Keywords: | quantum sensing;nanodiamond;nitrogen-vacancy center;radical;chemical reaction;T-1 spin relaxation time | Document URI: | http://hdl.handle.net/1942/33122 | ISSN: | 1936-0851 | e-ISSN: | 1936-086X | DOI: | 10.1021/acsnano.0c04010 | ISI #: | WOS:000586793400049 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2021 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
2010.11257.pdf | Non Peer-reviewed author version | 3.8 MB | Adobe PDF | View/Open |
acsnano.0c04010.pdf Restricted Access | Published version | 3.11 MB | Adobe PDF | View/Open Request a copy |
WEB OF SCIENCETM
Citations
58
checked on May 10, 2024
Page view(s)
40
checked on Sep 6, 2022
Download(s)
30
checked on Sep 6, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.