Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds

Gibbs, R.A.; Taylor, J.F.; Van Tassell, C.P.; Barendse, W.; Eversole, K.A.; Gill, C.A.; Green, R.D.; Hamernik, D.L.; Kappes, S.M.; Lien, S.; Matukumalli, L.K.; McEwan, J.C.; Nazareth, L.V.; Schnabel, R.D.; Weinstock, G.M.; Wheeler, D.A.; Ajmone-Marsan, P.; Barends, W.; Boettcher, P.J.; Caetano, A.R.; Garcia, J.F.; OlivierHanotte; Mariani, P.; Skow, L.C.; Sonstegard, T.S.; Williams, J.L.; Diallo, B.; Hailemariam, L.; Hanotte, O.; Martinez, M.L.; Morris, C.A.; Silva, L.O.C.; Spelman, R.J.; Mulatu, W.; Zhao, K.; Abbey, C.A.; Agaba, M.; Araujo, F.R.; Bunch, R.J.; Burton, J.; Gorni, C.; Harrison, B.E.; Luff, B.; Machado, M.A.; Mwakaya, J.; Plastow, G.; Sim, W.; Smith, T.; Thomas, M.B.; Valentini, A.; Williams, P.; Womack, J.; Woolliams, J.A.; Liu, Y.; Qin, X.; Worley, K.C.; Gao, C.; Jiang, H.; Moore, S.S.; Ren, Y.; Song, X.-Z.; Bustamante, C.D.; Hernandez, R.D.; Muzny, D.M.; Patil, S.; Lucas, A.S.; Fu, Q.; Kent, M.P.; Vega, R.; Matukumalli, A.; McWilliam, S.; Sclep, G.; Bryc, K.; Choi, J.; Gao, H.; Grefenstette, J.J.; Murdoch, B.; Stella, A.; Villa-Angulo, R.; Wright, M.; AERTS, Jan; Jann, O.; Negrini, R.; Goddard, M.E.; Hayes, B.J.; Bradley, D.G.; Da Silva, M.B.; Lau, L.P.L.; Liu, G.E.; Lynn, D.J.; Panzitta, F.; Dodds, K.G.

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/33737

Title:	Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds
Authors:	Gibbs, R.A. Taylor, J.F. Van Tassell, C.P. Barendse, W. Eversole, K.A. Gill, C.A. Green, R.D. Hamernik, D.L. Kappes, S.M. Lien, S. Matukumalli, L.K. McEwan, J.C. Nazareth, L.V. Schnabel, R.D. Weinstock, G.M. Wheeler, D.A. Ajmone-Marsan, P. Barends, W. Boettcher, P.J. Caetano, A.R. Garcia, J.F. OlivierHanotte Mariani, P. Skow, L.C. Sonstegard, T.S. Williams, J.L. Diallo, B. Hailemariam, L. Hanotte, O. Martinez, M.L. Morris, C.A. Silva, L.O.C. Spelman, R.J. Mulatu, W. Zhao, K. Abbey, C.A. Agaba, M. Araujo, F.R. Bunch, R.J. Burton, J. Gorni, C. Harrison, B.E. Luff, B. Machado, M.A. Mwakaya, J. Plastow, G. Sim, W. Smith, T. Thomas, M.B. Valentini, A. Williams, P. Womack, J. Woolliams, J.A. Liu, Y. Qin, X. Worley, K.C. Gao, C. Jiang, H. Moore, S.S. Ren, Y. Song, X.-Z. Bustamante, C.D. Hernandez, R.D. Muzny, D.M. Patil, S. Lucas, A.S. Fu, Q. Kent, M.P. Vega, R. Matukumalli, A. McWilliam, S. Sclep, G. Bryc, K. Choi, J. Gao, H. Grefenstette, J.J. Murdoch, B. Stella, A. Villa-Angulo, R. Wright, M. AERTS, Jan Jann, O. Negrini, R. Goddard, M.E. Hayes, B.J. Bradley, D.G. Da Silva, M.B. Lau, L.P.L. Liu, G.E. Lynn, D.J. Panzitta, F. Dodds, K.G.
Issue Date:	2009
Publisher:	AMER ASSOC ADVANCEMENT SCIENCE
Source:	SCIENCE, 324 (5926) , p. 528 -532
Abstract:	The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.
Document URI:	http://hdl.handle.net/1942/33737
Link to publication/dataset:	http://www.scopus.com/inward/record.url?eid=2-s2.0-65449132092&partnerID=MN8TOARS
ISBN:	00368075 10959203
ISSN:	0036-8075
e-ISSN:	1095-9203
DOI:	10.1126/science.1167936
ISI #:	000265411200051
Category:	A1
Type:	Journal Contribution
Appears in Collections:	Research publications

Show full item record

Google Scholar^TM

Check

Google ScholarTM

Altmetric

Google Scholar^TM