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http://hdl.handle.net/1942/33764
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DC Field | Value | Language |
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dc.contributor.author | Sara Aibar | - |
dc.contributor.author | Carmen Bravo González-Blas | - |
dc.contributor.author | Thomas Moerman | - |
dc.contributor.author | Vân Anh Huynh-Thu | - |
dc.contributor.author | Hana Imrichova | - |
dc.contributor.author | Gert Hulselmans | - |
dc.contributor.author | Florian Rambow | - |
dc.contributor.author | Jean-Christophe Marine | - |
dc.contributor.author | Pierre Geurts | - |
dc.contributor.author | AERTS, Jan | - |
dc.contributor.author | Joost van den Oord | - |
dc.contributor.author | Zeynep Kalender Atak | - |
dc.contributor.author | Jasper Wouters | - |
dc.contributor.author | Stein Aerts | - |
dc.date.accessioned | 2021-03-30T07:10:05Z | - |
dc.date.available | 2021-03-30T07:10:05Z | - |
dc.date.issued | 2017 | - |
dc.date.submitted | 2021-03-22T13:03:34Z | - |
dc.identifier.citation | Nature Methods, 14 (11) , p. 1083 -1086 | - |
dc.identifier.isbn | 15487105 15487091 | - |
dc.identifier.uri | http://hdl.handle.net/1942/33764 | - |
dc.description.abstract | We present SCENIC, a computational method for simultaneous gene regulatory network reconstruction and cell-state identification from single-cell RNA-seq data (http://scenic.aertslab.org). On a compendium of single-cell data from tumors and brain, we demonstrate that cis-regulatory analysis can be exploited to guide the identification of transcription factors and cell states. SCENIC provides critical biological insights into the mechanisms driving cellular heterogeneity. | - |
dc.language.iso | en | - |
dc.publisher | Springer Science and Business Media {LLC} | - |
dc.subject.other | Algorithms | - |
dc.subject.other | Animals | - |
dc.subject.other | Brain | - |
dc.subject.other | Cluster Analysis | - |
dc.subject.other | Gene Expression Profiling | - |
dc.subject.other | Humans | - |
dc.subject.other | Mice | - |
dc.subject.other | Gene Regulatory Networks | - |
dc.subject.other | Single-Cell Analysis | - |
dc.title | SCENIC: single-cell regulatory network inference and clustering | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1086 | - |
dc.identifier.issue | 11 | - |
dc.identifier.spage | 1083 | - |
dc.identifier.volume | 14 | - |
local.bibliographicCitation.jcat | A1 | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1038/nmeth.4463 | - |
dc.identifier.pmid | 28991892 | - |
dc.identifier.scopus | 2-s2.0-85032583384 | - |
dc.identifier.url | https://doi.org/10.1038/nmeth.4463 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | #NODATA# | - |
local.provider.type | Orcid | - |
local.uhasselt.uhpub | no | - |
local.uhasselt.international | no | - |
item.fullcitation | Sara Aibar; Carmen Bravo González-Blas; Thomas Moerman; Vân Anh Huynh-Thu; Hana Imrichova; Gert Hulselmans; Florian Rambow; Jean-Christophe Marine; Pierre Geurts; AERTS, Jan; Joost van den Oord; Zeynep Kalender Atak; Jasper Wouters & Stein Aerts (2017) SCENIC: single-cell regulatory network inference and clustering. In: Nature Methods, 14 (11) , p. 1083 -1086. | - |
item.fulltext | No Fulltext | - |
item.accessRights | Closed Access | - |
item.contributor | Sara Aibar | - |
item.contributor | Carmen Bravo González-Blas | - |
item.contributor | Thomas Moerman | - |
item.contributor | Vân Anh Huynh-Thu | - |
item.contributor | Hana Imrichova | - |
item.contributor | Gert Hulselmans | - |
item.contributor | Florian Rambow | - |
item.contributor | Jean-Christophe Marine | - |
item.contributor | Pierre Geurts | - |
item.contributor | AERTS, Jan | - |
item.contributor | Joost van den Oord | - |
item.contributor | Zeynep Kalender Atak | - |
item.contributor | Jasper Wouters | - |
item.contributor | Stein Aerts | - |
crisitem.journal.issn | 1548-7091 | - |
crisitem.journal.eissn | 1548-7105 | - |
Appears in Collections: | Research publications |
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