Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/33795
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dc.contributor.authorD'ONOFRIO, Valentino-
dc.contributor.authorMeersman, Agnes-
dc.contributor.authorVijgen, Sara-
dc.contributor.authorCartuyvels, Reinoud-
dc.contributor.authorMESSIAEN, Peter-
dc.contributor.authorGYSSENS, Inge-
dc.date.accessioned2021-03-31T13:10:02Z-
dc.date.available2021-03-31T13:10:02Z-
dc.date.issued2021-
dc.date.submitted2021-03-02T09:41:59Z-
dc.identifier.citationOpen Forum Infectious Diseases, 8 (1) (Art N° ofaa594)-
dc.identifier.issn2328-8957-
dc.identifier.urihttp://hdl.handle.net/1942/33795-
dc.description.abstractBackground. There is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department. Methods. A prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify independent risk factors. Results. Sequential organ failure assessment (SOFA) score of >= 2 and serum lactate of >= 2mmol/L were associated with all outcomes. Other independent risk factors were individual SOFA variables and systemic inflammatory response syndrome variables but varied per outcome. Mean arterial pressure <70 mmHg negatively impacted all outcomes. Conclusions. These readily available measurements can help with early risk stratification and prediction of prognosis.-
dc.description.sponsorshipThis work was funded by the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement 634137 and is part of the Fast Assay for Pathogen Identification and Characterisation project. Acknowledgments We thank Dr. Liesbeth Bruckers (Interuniversity institute for Biostatistics and Statistical Bioinformatics, Hasselt University) for providing statistical advice and reviewing the statistical methodology of this study. This study is part of the Limburg Clinical Research Center UHasselt-ZOL-Jessa, supported by the foundation Limburg Sterk Merk, Hasselt University, Ziekenhuis Oost-Limburg and Jessa Hospital. Financial support. This work was funded by the European Union’s Horizon 2020 Research and Innovation Program under Grant Agreement 634137 and is part of the Fast Assay for Pathogen Identification and Characterisation project-
dc.language.isoen-
dc.publisherOXFORD UNIV PRESS INC-
dc.rightsThe Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/ by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com DOI: 10.1093/ofid/ofaa594-
dc.subject.otherbacteremia-
dc.subject.otherbacteremia-
dc.subject.otheremergency department-
dc.subject.otheremergency department-
dc.subject.otherICU admission-
dc.subject.otherICU admission-
dc.subject.otherrisk factors-
dc.subject.otherrisk factors-
dc.subject.othersepsis-
dc.subject.othersepsis-
dc.titleRisk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study-
dc.typeJournal Contribution-
dc.identifier.issue1-
dc.identifier.volume8-
local.format.pages6-
local.bibliographicCitation.jcatA1-
dc.description.notesGyssens, IC (corresponding author), Radboud Univ Nijmegen, Dept Internal Med, Med Ctr, Geert Grootepl Zuid 10, NL-6525 GA Nijmegen, Netherlands.; Gyssens, IC (corresponding author), Radboud Univ Nijmegen, Radboud Ctr Infect Dis, Med Ctr, Nijmegen, Netherlands.-
dc.description.notesinge.gyssens@radboudumc.nl-
dc.description.otherGyssens, IC (corresponding author), Radboud Univ Nijmegen, Dept Internal Med, Med Ctr, Geert Grootepl Zuid 10, NL-6525 GA Nijmegen, Netherlands ; Radboud Univ Nijmegen, Radboud Ctr Infect Dis, Med Ctr, Nijmegen, Netherlands. inge.gyssens@radboudumc.nl-
local.publisher.placeJOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.bibliographicCitation.artnrofaa594-
dc.identifier.doi10.1093/ofid/ofaa594-
dc.identifier.pmid33511231-
dc.identifier.isiWOS:000610004000035-
local.provider.typewosris-
local.uhasselt.uhpubyes-
local.description.affiliation[D'Onofrio, Valentino; Messiaen, Peter; Gyssens, Inge C.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium.-
local.description.affiliation[D'Onofrio, Valentino; Messiaen, Peter] Jessa Hosp, Dept Infect Dis & Immun, Hasselt, Belgium.-
local.description.affiliation[D'Onofrio, Valentino; Gyssens, Inge C.] Radboud Univ Nijmegen, Dept Internal Med, Med Ctr, Geert Grootepl Zuid 10, NL-6525 GA Nijmegen, Netherlands.-
local.description.affiliation[D'Onofrio, Valentino; Gyssens, Inge C.] Radboud Univ Nijmegen, Radboud Ctr Infect Dis, Med Ctr, Nijmegen, Netherlands.-
local.description.affiliation[Meersman, Agnes] Jessa Hosp, Emergency Dept, Hasselt, Belgium.-
local.description.affiliation[Vijgen, Sara; Cartuyvels, Reinoud] Jessa Hosp, Clin Lab, Hasselt, Belgium.-
local.uhasselt.internationalyes-
item.contributorD'ONOFRIO, Valentino-
item.contributorMeersman, Agnes-
item.contributorVijgen, Sara-
item.contributorCartuyvels, Reinoud-
item.contributorMESSIAEN, Peter-
item.contributorGYSSENS, Inge-
item.fullcitationD'ONOFRIO, Valentino; Meersman, Agnes; Vijgen, Sara; Cartuyvels, Reinoud; MESSIAEN, Peter & GYSSENS, Inge (2021) Risk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study. In: Open Forum Infectious Diseases, 8 (1) (Art N° ofaa594).-
item.accessRightsOpen Access-
item.fulltextWith Fulltext-
item.validationecoom 2022-
crisitem.journal.issn2328-8957-
crisitem.journal.eissn2328-8957-
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