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http://hdl.handle.net/1942/33867
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DC Field | Value | Language |
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dc.contributor.author | Chichareon, Ply | - |
dc.contributor.author | van Klaveren, David | - |
dc.contributor.author | Modolo, Rodrigo | - |
dc.contributor.author | Kogame, Norihiro | - |
dc.contributor.author | Takahashi, Kuniaki | - |
dc.contributor.author | Chang, Chun-Chin | - |
dc.contributor.author | Tomaniak, Mariusz | - |
dc.contributor.author | Yuan, Jinqing | - |
dc.contributor.author | Xie, Lihua | - |
dc.contributor.author | Song, Ying | - |
dc.contributor.author | Qiao, Shubin | - |
dc.contributor.author | Yang, Yuejin | - |
dc.contributor.author | Guan, Changdong | - |
dc.contributor.author | Zurakowski, Aleksander | - |
dc.contributor.author | van Geuns, Robert-Jan | - |
dc.contributor.author | Sabate, Manel | - |
dc.contributor.author | Ong, Paul J. | - |
dc.contributor.author | Wykrzykowska, Joanna J. | - |
dc.contributor.author | Piek, Jan J. | - |
dc.contributor.author | Garg, Scot | - |
dc.contributor.author | Hamm, Christian | - |
dc.contributor.author | Steg, Gabriel | - |
dc.contributor.author | VRANCKX, Pascal | - |
dc.contributor.author | Valgimigli, Marco | - |
dc.contributor.author | Windecker, Stephan | - |
dc.contributor.author | Juni, Peter | - |
dc.contributor.author | Onuma, Yoshinobu | - |
dc.contributor.author | Steyerberg, Ewout | - |
dc.contributor.author | Xu, Bo | - |
dc.contributor.author | Serruys, Patrick W. | - |
dc.date.accessioned | 2021-04-06T13:58:05Z | - |
dc.date.available | 2021-04-06T13:58:05Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-03-09T12:15:10Z | - |
dc.identifier.citation | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 98 (7) , p. 1287-1297 | - |
dc.identifier.issn | 1522-1946 | - |
dc.identifier.uri | http://hdl.handle.net/1942/33867 | - |
dc.description.abstract | Aims We aimed to update the logistic clinical SYNTAX score to predict 2 year all-cause mortality after contemporary percutaneous coronary intervention (PCI). Methods and results We analyzed 15,883 patients in the GLOBAL LEADERS study who underwent PCI. The logistic clinical SYNTAX model was updated after imputing missing values by refitting the original model (refitted original model) and fitting an extended new model (new model, with, selection based on the Akaike Information Criterion). External validation was performed in 10,100 patients having PCI at Fu Wai hospital. Chronic obstructive pulmonary disease, prior stroke, current smoker, hemoglobin level, and white blood cell count were identified as additional independent predictors of 2 year all-cause mortality and included into the new model. The c-indexes of the original, refitted original and the new model in the derivation cohort were 0.74 (95% CI 0.72-0.76), 0.75 (95% CI 0.73-0.77), and 0.78 (95% CI 0.76-0.80), respectively. The c-index of the new model was lower in the validation cohort than in the derivation cohort, but still showed improved discriminative ability of the newly developed model (0.72; 95% CI 0.67-0.77) compared to the refitted original model (0.69; 95% CI 0.64-0.74). The models overestimated the observed 2 year all-cause mortality of 1.11% in the Chinese external validation cohort by 0.54 percentage points, indicating the need for calibration of the model to the Chinese patient population. Conclusions The new model of the logistic clinical SYNTAX score better predicts 2 year all-cause mortality after PCI than the original model. The new model could guide clinical decision making by risk stratifying patients undergoing PCI. | - |
dc.description.sponsorship | Biosensors International, AstraZeneca, and the Medicines Company GLOBAL LEADERS study was sponsored by the European Clinical Research Institute, which received funding from Biosensors International, AstraZeneca, and the Medicines Company. The study funders had no role in trial design, data collection, analysis, interpretation of the data, preparation, approval, or making a decision to submit the manuscript or publication. | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.rights | 2021 Wiley Periodicals LLC. Free access | - |
dc.subject.other | coronary artery disease | - |
dc.subject.other | percutaneous coronary intervention | - |
dc.subject.other | risk score | - |
dc.subject.other | risk stratification | - |
dc.title | Predicting 2-year all-cause mortality after contemporary PCI: Updating the logistic clinical SYNTAX score | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1297 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1287 | - |
dc.identifier.volume | 98 | - |
local.format.pages | 11 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.other | Xu, B (corresponding author), Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fu Wai Hosp, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China ; Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, A 167,Beilishi Rd, Beijing 100037, Peoples R China. Serruys, PW (corresponding author), Natl Univ Ireland Galway, Dept Cardiol, Galway, Ireland ; Imperial Coll London, NHLI, London, England ; Natl Univ Ireland Galway NUIG, Cardiol, Univ Rd, Galway H91 TK33, Ireland. bxu@citmd.com; patrick.w.j.c.serruys@pwserruys.com | - |
local.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1002/ccd.29490 | - |
dc.identifier.pmid | 33539048 | - |
dc.identifier.isi | 000614528500001 | - |
dc.identifier.eissn | 1522-726X | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Chichareon, Ply; Modolo, Rodrigo; Kogame, Norihiro; Takahashi, Kuniaki; Wykrzykowska, Joanna J.; Piek, Jan J.] Univ Amsterdam, Amsterdam UMC, Amsterdam Cardiovasc Sci, Heart Ctr,Dept Clin & Expt Cardiol, Amsterdam, Netherlands. | - |
local.description.affiliation | [Chichareon, Ply] Prince Songkla Univ, Fac Med, Dept Internal Med, Cardiol Unit, Hat Yai, Thailand. | - |
local.description.affiliation | [van Klaveren, David] Erasmus Univ, Dept Publ Hlth, Med Ctr, Rotterdam, Netherlands. | - |
local.description.affiliation | [van Klaveren, David] Tufts Med Ctr, Inst Clin Res & Hlth Policy Studies, Predict Analyt & Comparat Effectiveness Ctr, Boston, MA 02111 USA. | - |
local.description.affiliation | [Modolo, Rodrigo] Univ Campinas UNICAMP, Dept Internal Med, Div Cardiol, Campinas, Brazil. | - |
local.description.affiliation | [Chang, Chun-Chin; Tomaniak, Mariusz; van Geuns, Robert-Jan] Erasmus Univ, Dept Cardiol, Med Ctr, Rotterdam, Netherlands. | - |
local.description.affiliation | [Tomaniak, Mariusz] Med Univ Warsaw, Dept Cardiol 1, Warsaw, Poland. | - |
local.description.affiliation | [Yuan, Jinqing; Xie, Lihua; Song, Ying; Qiao, Shubin; Yang, Yuejin; Guan, Changdong; Xu, Bo] Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fu Wai Hosp, Natl Clin Res Ctr Cardiovasc Dis, Beijing, Peoples R China. | - |
local.description.affiliation | [Zurakowski, Aleksander] Amer Heart Poland, Ctr Cardiovasc Res & Dev, Katowice, Poland. | - |
local.description.affiliation | [Sabate, Manel] Inst Invest Biomed August Pi & Sunyer IDIBAPS, Univ Hosp Clin, Barcelona, Spain. | - |
local.description.affiliation | [Ong, Paul J.] Tan Tock Seng Hosp, Novena, Singapore. | - |
local.description.affiliation | [Garg, Scot] East Lancashire Hosp NHS Trust, Blackburn, Lancs, England. | - |
local.description.affiliation | [Hamm, Christian] Campus Univ Giessen, Kerckhoff Heart Ctr, Bad Nauheim, Germany. | - |
local.description.affiliation | [Steg, Gabriel] Univ Paris Diderot, French Alliance Cardiovasc Trials, Hop Bichat, AP HP, Paris, France. | - |
local.description.affiliation | [Steg, Gabriel] INSERM U 1148, Paris, France. | - |
local.description.affiliation | [Steg, Gabriel] Imperial Coll, Royal Brompton Hosp, London, England. | - |
local.description.affiliation | [Vranckx, Pascal] Hasselt Univ, Fac Med & Life Sci, Hartctr Hasselt, Hasselt, Belgium. | - |
local.description.affiliation | [Valgimigli, Marco; Windecker, Stephan] Bern Univ Hosp, Dept Cardiol, Bern, Switzerland. | - |
local.description.affiliation | [Juni, Peter] Univ Toronto, Li Ka Shing Knowledge Inst, Appl Hlth Res Ctr, St Michaels Hosp,Dept Med, Toronto, ON, Canada. | - |
local.description.affiliation | [Onuma, Yoshinobu; Serruys, Patrick W.] Natl Univ Ireland Galway, Dept Cardiol, Galway, Ireland. | - |
local.description.affiliation | [Steyerberg, Ewout] Leiden Univ, Dept Biomed Data Sci, Med Ctr, Leiden, Netherlands. | - |
local.description.affiliation | [Serruys, Patrick W.] Imperial Coll London, NHLI, London, England. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Chichareon, Ply; van Klaveren, David; Modolo, Rodrigo; Kogame, Norihiro; Takahashi, Kuniaki; Chang, Chun-Chin; Tomaniak, Mariusz; Yuan, Jinqing; Xie, Lihua; Song, Ying; Qiao, Shubin; Yang, Yuejin; Guan, Changdong; Zurakowski, Aleksander; van Geuns, Robert-Jan; Sabate, Manel; Ong, Paul J.; Wykrzykowska, Joanna J.; Piek, Jan J.; Garg, Scot; Hamm, Christian; Steg, Gabriel; VRANCKX, Pascal; Valgimigli, Marco; Windecker, Stephan; Juni, Peter; Onuma, Yoshinobu; Steyerberg, Ewout; Xu, Bo & Serruys, Patrick W. (2021) Predicting 2-year all-cause mortality after contemporary PCI: Updating the logistic clinical SYNTAX score. In: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 98 (7) , p. 1287-1297. | - |
item.contributor | Chichareon, Ply | - |
item.contributor | van Klaveren, David | - |
item.contributor | Modolo, Rodrigo | - |
item.contributor | Kogame, Norihiro | - |
item.contributor | Takahashi, Kuniaki | - |
item.contributor | Chang, Chun-Chin | - |
item.contributor | Tomaniak, Mariusz | - |
item.contributor | Yuan, Jinqing | - |
item.contributor | Xie, Lihua | - |
item.contributor | Song, Ying | - |
item.contributor | Qiao, Shubin | - |
item.contributor | Yang, Yuejin | - |
item.contributor | Guan, Changdong | - |
item.contributor | Zurakowski, Aleksander | - |
item.contributor | van Geuns, Robert-Jan | - |
item.contributor | Sabate, Manel | - |
item.contributor | Ong, Paul J. | - |
item.contributor | Wykrzykowska, Joanna J. | - |
item.contributor | Piek, Jan J. | - |
item.contributor | Garg, Scot | - |
item.contributor | Hamm, Christian | - |
item.contributor | Steg, Gabriel | - |
item.contributor | VRANCKX, Pascal | - |
item.contributor | Valgimigli, Marco | - |
item.contributor | Windecker, Stephan | - |
item.contributor | Juni, Peter | - |
item.contributor | Onuma, Yoshinobu | - |
item.contributor | Steyerberg, Ewout | - |
item.contributor | Xu, Bo | - |
item.contributor | Serruys, Patrick W. | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2022 | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1522-1946 | - |
crisitem.journal.eissn | 1522-726X | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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Predicting 2‐year all‐cause mortality after contemporary PCI_ Updating the logistic clinical SYNTAX score.pdf | Published version | 2.27 MB | Adobe PDF | View/Open |
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