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http://hdl.handle.net/1942/33897
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DC Field | Value | Language |
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dc.contributor.author | Makarova, Katerina | - |
dc.contributor.author | Sajkowska-Kozielewicz, Joanna J. | - |
dc.contributor.author | Zawada, Katarzyna | - |
dc.contributor.author | Olchowik-Grabarek, Ewa | - |
dc.contributor.author | CIACH, Michal | - |
dc.contributor.author | Gogolewski, Krzysztof | - |
dc.contributor.author | Dobros, Natalia | - |
dc.contributor.author | Ciechowicz, Paulina | - |
dc.contributor.author | Freichels, Helene | - |
dc.contributor.author | Gambin, Anna | - |
dc.date.accessioned | 2021-04-12T15:00:40Z | - |
dc.date.available | 2021-04-12T15:00:40Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-03-30T13:03:30Z | - |
dc.identifier.citation | Scientific reports, 11 (1) (Art N° 3989) | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/1942/33897 | - |
dc.description.abstract | The polyphenol content and antioxidant capacity of hyperforin and hypericin-standardized H. perforatum L. extracts may vary due to the harvest time. In this work, ethanol and ethanol-water extracts of air-dried and lyophilized flowers of H. perforatum L., collected throughout a vegetation season in central Poland, were studied. Air-dried flowers extracts had higher polyphenol (371 mg GAE/g) and flavonoid (160 mg CAE/g) content, DPPH radical scavenging (1672 mg DPPH/g), ORAC (5214 mu mol TE/g) and FRAP (2.54 mmol Fe2+/g) than lyophilized flowers extracts (238 mg GAE/g, 107 mg CAE/g, 1287 mg DPPH/g, 3313 mu mol TE/g and 0.31 mmol Fe2+/g, respectively). Principal component analysis showed that the collection date influenced the flavonoid and polyphenol contents and FRAP of ethanol extracts, and DPPH and ORAC values of ethanol-water extracts. The ethanol extracts with the highest polyphenol and flavonoid content protected human erythrocytes against bisphenol A-induced damage. Both high field and benchtop NMR spectra of selected extracts, revealed differences in composition caused by extraction solvent and raw material collection date. Moreover, we have shown that benchtop NMR can be used to detect the compositional variation of extracts if the assignment of signals is done previously. | - |
dc.description.sponsorship | The research was supported by the National Science Centre (NSC grant SONATA 2013/11/D/NZ7/02346). | - |
dc.language.iso | en | - |
dc.publisher | NATURE RESEARCH | - |
dc.rights | The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | - |
dc.subject.other | Anthracenes | - |
dc.subject.other | Antioxidants | - |
dc.subject.other | Benzhydryl Compounds | - |
dc.subject.other | Ethanol | - |
dc.subject.other | Flavonoids | - |
dc.subject.other | Flowers | - |
dc.subject.other | Humans | - |
dc.subject.other | Hypericum | - |
dc.subject.other | Perylene | - |
dc.subject.other | Phenols | - |
dc.subject.other | Phloroglucinol | - |
dc.subject.other | Plant Extracts | - |
dc.subject.other | Poland | - |
dc.subject.other | Polyphenols | - |
dc.subject.other | Principal Component Analysis | - |
dc.subject.other | Terpenes | - |
dc.title | Harvest time affects antioxidant capacity, total polyphenol and flavonoid content of Polish St John’s wort’s (Hypericum perforatum L.) flowers | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 11 | - |
local.format.pages | 12 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Makarova, K (corresponding author), Med Univ Warsaw, Dept Phys Chem, Chair Phys Pharm & Bioanal, Fac Pharm,Lab Med Div, Banacha 1, PL-02097 Warsaw, Poland. | - |
dc.description.notes | Katerina.makarova@gmail.com | - |
dc.description.other | Makarova, K (corresponding author), Med Univ Warsaw, Dept Phys Chem, Chair Phys Pharm & Bioanal, Fac Pharm,Lab Med Div, Banacha 1, PL-02097 Warsaw, Poland. Katerina.makarova@gmail.com | - |
local.publisher.place | HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 3989 | - |
dc.identifier.doi | 10.1038/s41598-021-83409-4 | - |
dc.identifier.pmid | 33597594 | - |
dc.identifier.isi | WOS:000621344600014 | - |
dc.contributor.orcid | Gambin, Anna/0000-0003-3476-3017 | - |
dc.identifier.eissn | 2045-2322 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Makarova, Katerina; Sajkowska-Kozielewicz, Joanna J.; Zawada, Katarzyna; Dobros, Natalia; Ciechowicz, Paulina] Med Univ Warsaw, Dept Phys Chem, Chair Phys Pharm & Bioanal, Fac Pharm,Lab Med Div, Banacha 1, PL-02097 Warsaw, Poland. | - |
local.description.affiliation | [Olchowik-Grabarek, Ewa] Univ Bialystok, Lab Mol Biophys, Dept Microbiol & Biotechnol, Fac Biol, Ciolkowskiego 1J, PL-15245 Bialystok, Poland. | - |
local.description.affiliation | [Ciach, Michal Aleksander; Gogolewski, Krzysztof; Gambin, Anna] Univ Warsaw, Fac Math Informat & Mech, Stefana Banacha 2, PL-02097 Warsaw, Poland. | - |
local.description.affiliation | [Ciach, Michal Aleksander] Hasselt Univ, Ctr Stat, B-3590 Limburg, Belgium. | - |
local.description.affiliation | [Freichels, Helene] Magritek GmbH, Philipsstr 8, D-52068 Aachen, Germany. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Makarova, Katerina; Sajkowska-Kozielewicz, Joanna J.; Zawada, Katarzyna; Olchowik-Grabarek, Ewa; CIACH, Michal; Gogolewski, Krzysztof; Dobros, Natalia; Ciechowicz, Paulina; Freichels, Helene & Gambin, Anna (2021) Harvest time affects antioxidant capacity, total polyphenol and flavonoid content of Polish St John’s wort’s (Hypericum perforatum L.) flowers. In: Scientific reports, 11 (1) (Art N° 3989). | - |
item.fulltext | With Fulltext | - |
item.contributor | Makarova, Katerina | - |
item.contributor | Sajkowska-Kozielewicz, Joanna J. | - |
item.contributor | Zawada, Katarzyna | - |
item.contributor | Olchowik-Grabarek, Ewa | - |
item.contributor | CIACH, Michal | - |
item.contributor | Gogolewski, Krzysztof | - |
item.contributor | Dobros, Natalia | - |
item.contributor | Ciechowicz, Paulina | - |
item.contributor | Freichels, Helene | - |
item.contributor | Gambin, Anna | - |
item.validation | ecoom 2022 | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 2045-2322 | - |
crisitem.journal.eissn | 2045-2322 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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s41598-021-83409-4.pdf | Published version | 1.56 MB | Adobe PDF | View/Open |
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