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http://hdl.handle.net/1942/33916
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DC Field | Value | Language |
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dc.contributor.author | BUSSCHOTS, Dana | - |
dc.contributor.author | KREMER, Cécile | - |
dc.contributor.author | KOC, Ozgur | - |
dc.contributor.author | HEYENS, Leen | - |
dc.contributor.author | BIELEN, Rob | - |
dc.contributor.author | Apers, Ludwig | - |
dc.contributor.author | Florence, Eric | - |
dc.contributor.author | MESSIAEN, Peter | - |
dc.contributor.author | Van Laethem, Kristel | - |
dc.contributor.author | Van Wijngaerden, Eric | - |
dc.contributor.author | Nevens, Frederik | - |
dc.contributor.author | HENS, Niel | - |
dc.contributor.author | ROBAEYS, Geert | - |
dc.date.accessioned | 2021-04-14T13:37:36Z | - |
dc.date.available | 2021-04-14T13:37:36Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-04-12T09:20:54Z | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 105 , p. 217 -223 | - |
dc.identifier.issn | 1201-9712 | - |
dc.identifier.uri | http://hdl.handle.net/1942/33916 | - |
dc.description.abstract | Objectives The Belgian population of people living with HIV (PLHIV) has unrestricted access to direct-acting antiviral (DAA) treatment for hepatitis C virus (HCV) infection, since 2017. International literature claims that half of the patients remain untreated in high-income countries with unrestricted access to DAA. This study was initiated to provide an overview of the present situation in Belgium and recommendations for HCV care in PLHIV in other regions. Methods This was a retrospective, multicenter study of PLHIV in Belgium, from January 1, 2007 to December 31, 2018. The HCV cascade of care was examined. Results Out of 4607 unique PLHIV, 322 (7.0%) tested positive for HCV antibody and HCV RNA positivity was seen in 289 (6.3%). Of those with a proven HCV infection, 207/289 (71.6%) initiated treatment. Of the 171 (82.6%) persons with a sustained virologic response (SVR), 16 (9.4%) subjects were reinfected. Conclusions We present a care cascade of 4607 PLHIV in Belgium. Treatment initiation and SVR rates were high compared to other regions. Implementation of a national HCV register to track progress and yearly screening, especially in PLHIV with high-risk behavior, remains crucial. Identifying reasons for not initiating treatment is necessary to achieve elimination of HCV in PLHIV by 2030. | - |
dc.description.sponsorship | Funding This study is part of the project G0B2317N funded by the Fund of Scientific Research — Flanders(FWO). Acknowledgments This study is part of the project G0B2317N funded by the Fund of Scientific Research — Flanders (FWO). The PhD authors are part of the ‘Limburg ClinicalResearchCenter (LCRC), supported bythe foundation Limburg Sterk Merk, province of Limburg, Flemish government, Hasselt University, Ziekenhuis Oost-Limburg and Jessa Hospital. Special thanks to Salima Gharmaoui, Eveline Van Steenkiste, and Lize Cuypers for their contribution to data management. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | Hepatitis C | - |
dc.subject.other | HIV | - |
dc.subject.other | Cascade of care | - |
dc.subject.other | Treatment | - |
dc.subject.other | Recommendations | - |
dc.subject.other | High-income country | - |
dc.title | The hepatitis C cascade of care in the Belgian HIV population: one step closer to elimination | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 223 | - |
dc.identifier.spage | 217 | - |
dc.identifier.volume | 105 | - |
local.format.pages | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.ijid.2021.02.068 | - |
dc.identifier.isi | 000680208600034 | - |
dc.identifier.eissn | 1878-3511 | - |
local.provider.type | CrossRef | - |
local.uhasselt.international | yes | - |
item.accessRights | Open Access | - |
item.contributor | BUSSCHOTS, Dana | - |
item.contributor | KREMER, Cécile | - |
item.contributor | KOC, Ozgur | - |
item.contributor | HEYENS, Leen | - |
item.contributor | BIELEN, Rob | - |
item.contributor | Apers, Ludwig | - |
item.contributor | Florence, Eric | - |
item.contributor | MESSIAEN, Peter | - |
item.contributor | Van Laethem, Kristel | - |
item.contributor | Van Wijngaerden, Eric | - |
item.contributor | Nevens, Frederik | - |
item.contributor | HENS, Niel | - |
item.contributor | ROBAEYS, Geert | - |
item.fullcitation | BUSSCHOTS, Dana; KREMER, Cécile; KOC, Ozgur; HEYENS, Leen; BIELEN, Rob; Apers, Ludwig; Florence, Eric; MESSIAEN, Peter; Van Laethem, Kristel; Van Wijngaerden, Eric; Nevens, Frederik; HENS, Niel & ROBAEYS, Geert (2021) The hepatitis C cascade of care in the Belgian HIV population: one step closer to elimination. In: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 105 , p. 217 -223. | - |
item.validation | ecoom 2022 | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1201-9712 | - |
crisitem.journal.eissn | 1878-3511 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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PIIS1201971221001545.pdf | Published version | 748.7 kB | Adobe PDF | View/Open |
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