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http://hdl.handle.net/1942/33984
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DC Field | Value | Language |
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dc.contributor.author | VERBRUGGE, Frederik | - |
dc.contributor.author | Reddy, Yogesh N., V | - |
dc.contributor.author | Sorimachi, Hidemi | - |
dc.contributor.author | Omote, Kazunori | - |
dc.contributor.author | Carter, Rickey E. | - |
dc.contributor.author | Borlaug, Barry A. | - |
dc.date.accessioned | 2021-04-26T10:02:03Z | - |
dc.date.available | 2021-04-26T10:02:03Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-04-13T12:16:10Z | - |
dc.identifier.citation | EUROPEAN JOURNAL OF HEART FAILURE, 23(6), p. 954-963 | - |
dc.identifier.uri | http://hdl.handle.net/1942/33984 | - |
dc.description.abstract | Aims To investigate the prognostic value of diagnostic scores for heart failure (HF) with preserved ejection fraction (HFpEF). Methods and results Consecutive patients with HFpEF admitted for unequivocal decompensated HF treated with intravenous loop diuretics were evaluated (n = 443; mean age 78 +/- 12 years; 60% women). The HFA-PEFF and H2FPEF scores were calculated for all patients with echocardiography data available within 1 year and the population was stratified according to HFA-PEFF scores 2-4 (n = 79), 5 (n = 93), or 6 (n = 271) and H2FPEF score probabilities <90% (n = 80), 90-95% (n = 61), and 96-100% (n = 293). HF readmission rates (95% confidence intervals) increased from 28.9 (22.7-35.0) per 100 patient-years in HFA-PEFF 2-4 to 46.0 (38.5-53.5) in HFA-PEFF 5 and 45.0 (40.1-49.8) in HFA-PEFF 6. Similarly, HF readmission rates increased with increasing H2FPEF probability: <0.90 [31.8 (25.3-38.2) per 100 patient-years], 0.90-0.95 [41.5 (32.9-50.1)], and 0.96-1.00 [45.9 (41.2-50.6]. Median survival was 65 months (36-89 months) in HFA-PEFF score 2-4, 45 months (26-59 months) in HFA-PEFF score 5, and 28 months (22-42 months) in HFA-PEFF score 6 (P < 0.001), while the hazard ratio (95% confidence interval) for all-cause mortality was 1.16 (1.02-1.32) per 0.10 increase in H2FPEF probability. Conclusions Among patients hospitalized with HFpEF, higher HFpEF probability according to diagnostic scores is associated with increased risk of subsequent HF readmissions and all-cause mortality. | - |
dc.description.sponsorship | F.H.V. is supported by a Fellowship of the Belgian American Educational Foundation (B.A.E.F.) and by the Special Research Fund (BOF) of Hasselt University (BOF19PD04). B.A.B. is supported by RO1 HL128526 from the National Heart, Lung, and Blood Institute. | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject.other | Cause of death | - |
dc.subject.other | Diastolic heart failure | - |
dc.subject.other | Mortality | - |
dc.subject.other | Patient readmission | - |
dc.subject.other | Risk assessment | - |
dc.title | Diagnostic scores predict morbidity and mortality in patients hospitalized for heart failure with preserved ejection fraction | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 963 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 954 | - |
dc.identifier.volume | 23 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Borlaug, BA (corresponding author), Mayo Clink & Fdn, 200 First St SW, Rochester, MN 55905 USA. | - |
dc.description.notes | borlaug.barry@mayo.edu | - |
dc.description.other | Borlaug, BA (corresponding author), Mayo Clink & Fdn, 200 First St SW, Rochester, MN 55905 USA. borlaug.barry@mayo.edu | - |
local.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1002/ejhf.2142 | - |
dc.identifier.isi | WOS:000626761200001 | - |
dc.contributor.orcid | Verbrugge, Frederik Hendrik/0000-0003-0599-9290; Borlaug, | - |
dc.contributor.orcid | Barry/0000-0001-9375-0596; Omote, Kazunori/0000-0002-8132-7173 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Verbrugge, Frederik H.; Reddy, Yogesh N., V; Sorimachi, Hidemi; Omote, Kazunori; Borlaug, Barry A.] Mayo Clin, Dept Cardiovasc Dis, Rochester, MN USA. | - |
local.description.affiliation | [Verbrugge, Frederik H.] Hasselt Univ, Fac Med & Life Sci, Biomed Res Inst, Hasselt, Belgium. | - |
local.description.affiliation | [Carter, Rickey E.] Mayo Clin, Dept Hlth Sci Res, Jacksonville, FL 32224 USA. | - |
local.uhasselt.international | yes | - |
item.contributor | VERBRUGGE, Frederik | - |
item.contributor | Reddy, Yogesh N., V | - |
item.contributor | Sorimachi, Hidemi | - |
item.contributor | Omote, Kazunori | - |
item.contributor | Carter, Rickey E. | - |
item.contributor | Borlaug, Barry A. | - |
item.validation | ecoom 2022 | - |
item.fullcitation | VERBRUGGE, Frederik; Reddy, Yogesh N., V; Sorimachi, Hidemi; Omote, Kazunori; Carter, Rickey E. & Borlaug, Barry A. (2021) Diagnostic scores predict morbidity and mortality in patients hospitalized for heart failure with preserved ejection fraction. In: EUROPEAN JOURNAL OF HEART FAILURE, 23(6), p. 954-963. | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1388-9842 | - |
crisitem.journal.eissn | 1879-0844 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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European J of Heart Fail - 2021 - Verbrugge - Diagnostic scores predict morbidity and mortality in patients hospitalized.pdf | Published version | 1.73 MB | Adobe PDF | View/Open |
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