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http://hdl.handle.net/1942/35723
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Marincowitz, Clara | - |
dc.contributor.author | Webster, Ingrid | - |
dc.contributor.author | Westcott, Corli | - |
dc.contributor.author | Goswami, Nandu | - |
dc.contributor.author | DE BOEVER, Patrick | - |
dc.contributor.author | Seidel, Gerald | - |
dc.contributor.author | Strijdom, Hans | - |
dc.date.accessioned | 2021-10-27T11:55:31Z | - |
dc.date.available | 2021-10-27T11:55:31Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-09-17T12:51:39Z | - |
dc.identifier.citation | CARDIOVASCULAR JOURNAL OF AFRICA, 32 (3) , p. 133 -140 | - |
dc.identifier.uri | http://hdl.handle.net/1942/35723 | - |
dc.description.abstract | Aim: Flow-mediated dilatation (FMD) and retinal vascular analysis (RVA) may assist in predicting cardiovascular disease (CVD) but are poorly characterised in South Africa. We recorded baseline FMD and retinal vascular widths in healthy participants, and investigated associations with cardiovascular risk factors. Methods: Endothelial function (measured with FMD), microvascular structure (evaluated via fundus image analysis) and major CVD risk factors were assessed in 66 participants from Cape Town. Results: Median FMD% was 9.6%, with higher values in females. Mean retinal arteriolar and venular widths were similar to 156 and similar to 250 mu m, respectively. FMD was not associated with CVD risk factors. Hypertension was associated with narrower retinal arterioles and venules. Conclusions: We report novel baseline FMD data in healthy South African adults from the Western Cape, and show that retinal microvascular calibres are associated with blood pressure. Our baseline FMD and RVA data could serve as a reference for future studies in South Africa. | - |
dc.description.sponsorship | ERAfrica programme of the EU; Department of Science and Technology in South Africa [DST/CON 0077/2014]; Belgian Science Policy in Belgium [BL/67/eranet03]; Osterreichische Agentur fur internationale Mobilitat und Kooperation in Bildung, Wissenschaft und Forschung; in Austria [KEF-Projekt P202]; National Research Foundation of South GmbH (OAD) Africa National Research Foundation - South Africa [CSUR13082330472]; National Research Foundation (NRF) of South Africa Research Career Advancement (RCA) award | - |
dc.language.iso | en | - |
dc.publisher | CLINICS CARDIVE PUBL PTY LTD | - |
dc.subject.other | vascular health | - |
dc.subject.other | endothelial function | - |
dc.subject.other | flow-mediated dilatation | - |
dc.subject.other | retinal imaging | - |
dc.subject.other | cardiovascular risk | - |
dc.title | Vascular health assessment with flow-mediated dilatation and retinal image analysis: a pilot study in an adult population from Cape Town | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 140 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 133 | - |
dc.identifier.volume | 32 | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Webster, I (corresponding author), Stellenbosch Univ, Ctr Cardiometab Res Africa, Div Med Physiol, Cape Town, South Africa. | - |
dc.description.notes | iwebster@sun.ac.za | - |
local.publisher.place | PO BOX 1013, DURBANVILLE, 7551, SOUTH AFRICA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.5830/CVJA-2020-046 | - |
dc.identifier.isi | WOS:000672606600005 | - |
dc.contributor.orcid | De Boever, Patrick/0000-0002-5197-8215; Strijdom, | - |
dc.contributor.orcid | Hans/0000-0003-3726-9153 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Marincowitz, Clara; Webster, Ingrid; Westcott, Corli; Strijdom, Hans] Stellenbosch Univ, Ctr Cardiometab Res Africa, Div Med Physiol, Cape Town, South Africa. | - |
local.description.affiliation | [Goswami, Nandu] Med Univ Graz, Dept Physiol, Graz, Austria. | - |
local.description.affiliation | [Goswami, Nandu] Med Univ Graz, Otto Loewi Res Ctr, Graz, Austria. | - |
local.description.affiliation | [De Boever, Patrick] Flemish Inst Technol Res VITO, Hlth Unit, Mol, Belgium. | - |
local.description.affiliation | [De Boever, Patrick] Hasselt Univ, Ctr Environm Sci, Diepenbeek, Belgium. | - |
local.description.affiliation | [De Boever, Patrick] Univ Antwerp, Dept Biol, Antwerp, Belgium. | - |
local.description.affiliation | [Seidel, Gerald] Med Univ Graz, Dept Ophthalmol, Graz, Austria. | - |
local.uhasselt.international | yes | - |
item.validation | ecoom 2022 | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Marincowitz, Clara; Webster, Ingrid; Westcott, Corli; Goswami, Nandu; DE BOEVER, Patrick; Seidel, Gerald & Strijdom, Hans (2021) Vascular health assessment with flow-mediated dilatation and retinal image analysis: a pilot study in an adult population from Cape Town. In: CARDIOVASCULAR JOURNAL OF AFRICA, 32 (3) , p. 133 -140. | - |
item.accessRights | Open Access | - |
item.contributor | Marincowitz, Clara | - |
item.contributor | Webster, Ingrid | - |
item.contributor | Westcott, Corli | - |
item.contributor | Goswami, Nandu | - |
item.contributor | DE BOEVER, Patrick | - |
item.contributor | Seidel, Gerald | - |
item.contributor | Strijdom, Hans | - |
crisitem.journal.issn | 1995-1892 | - |
crisitem.journal.eissn | 1680-0745 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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180569.pdf | Published version | 105.24 kB | Adobe PDF | View/Open |
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