Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/35887
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Feng, YM | - |
dc.contributor.author | Thijs, L | - |
dc.contributor.author | Zhang , ZY | - |
dc.contributor.author | BIJNENS, Esmee | - |
dc.contributor.author | Yang, WY | - |
dc.contributor.author | Wei, FF | - |
dc.contributor.author | JANSSEN, Bram | - |
dc.contributor.author | NAWROT, Tim | - |
dc.contributor.author | Staessen, JA | - |
dc.date.accessioned | 2021-11-25T12:55:23Z | - |
dc.date.available | 2021-11-25T12:55:23Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-09-13T15:12:42Z | - |
dc.identifier.citation | Scientific reports (Nature Publishing Group), 11 (1) (Art N° 14646) | - |
dc.identifier.uri | http://hdl.handle.net/1942/35887 | - |
dc.description.abstract | From 1990 until 2017, global air-pollution related mortality increased by 40%. Few studies addressed the renal responses to ultrafine particulate [<= 2.5 mu m (PM2.5)], including black carbon (BC), which penetrate into the blood stream. In a Flemish population study, glomerular filtration estimated from serum creatinine (eGFR) and the urinary albumin-to-creatinine ratio were measured in 2005-2009 in 820 participants (women, 50.7%; age, 51.1 years) with follow-up of 523 after 4.7 years (median). Serum creatinine, eGFR, chronic kidney disease (eGFR<60 mL/min/1.73 m(2)) and microalbuminuria (>3.5/>2.5 mg per mmol creatinine in women/men) were correlated in individual participants via their residential address with PM2.5 [median 13.1 (range 0.3-2.9) mu g/m(3)] and BC [1.1 (0.3-18) mu g/m(3)], using mixed models accounting for address clusters. Cross-sectional and longitudinally, no renal outcome was associated with PM2.5 or BC in models adjusted for sex and baseline or time varying covariables, including age, blood pressure, heart rate, body mass index, plasma glucose, the total-to-HDL serum cholesterol ratio, alcohol intake, smoking, physical activity, socioeconomic class, and antihypertensive treatment. The subject-level geocorrelations of eGFR change with to BC and PM2.5 were 0.13 and 0.02, respectively (P >= 0.68). In conclusion, in a population with moderate exposure, renal function was unrelated to ultrafine particulate. | - |
dc.description.sponsorship | FLEMENGHO was supported by the European Union (Grants IC15-CT98-0329-EPOGH, LSHM CT 037093-InGenious HyperCare, HEALTH-201550-HyperGenes, HEALTH-278249-EU-MASCARA, HEALTH-305507 HOMAGE), the European Research Council (Advanced Researcher Grant-2011–294713-EPLORE and Proof-of-Concept Grant-713601 uPROPHET), the European Research Area Net for Cardiovascular Diseases (JTC2017-046-PROACT), and the Research Foundation Flanders, Ministry of the Flemish Community, Brussels, Belgium. APPREMED (URL: http://www.appremed.org) received a non-binding grant from OMRON Healthcare Co., Ltd., Kyoto, Japan. Te National Science Fund in China (Grant Numbers: 81470566 and 81670765) supported collaboration between Youan Hospital, Beijing, China and the Research Unit Hypertension and Cardiovascular Epidemiology, Leuven, Belgium. Bram Janssen is a postdoctoral fellow supported by the Research Foundation Flanders (Grant Number: 12W3218). Te authors gratefully acknowledge the expert clerical assistance of Vera De Leebeeck and Renilde Wolfs, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium. | - |
dc.language.iso | en | - |
dc.publisher | NATURE RESEARCH | - |
dc.rights | The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | - |
dc.title | Glomerular function in relation to fine airborne particulate matter in a representative population sample | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 11 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 14646 | - |
dc.identifier.doi | 10.1038/s41598-021-94136-1 | - |
dc.identifier.pmid | 34282189 | - |
dc.identifier.isi | 000675839300013 | - |
local.provider.type | Web of Science | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.contributor | Feng, YM | - |
item.contributor | Thijs, L | - |
item.contributor | Zhang , ZY | - |
item.contributor | BIJNENS, Esmee | - |
item.contributor | Yang, WY | - |
item.contributor | Wei, FF | - |
item.contributor | JANSSEN, Bram | - |
item.contributor | NAWROT, Tim | - |
item.contributor | Staessen, JA | - |
item.fullcitation | Feng, YM; Thijs, L; Zhang , ZY; BIJNENS, Esmee; Yang, WY; Wei, FF; JANSSEN, Bram; NAWROT, Tim & Staessen, JA (2021) Glomerular function in relation to fine airborne particulate matter in a representative population sample. In: Scientific reports (Nature Publishing Group), 11 (1) (Art N° 14646). | - |
item.validation | ecoom 2022 | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 2045-2322 | - |
crisitem.journal.eissn | 2045-2322 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Glomerular function in relation to fine airborne particulate matter in a representative population sample.pdf | Published version | 1.42 MB | Adobe PDF | View/Open |
WEB OF SCIENCETM
Citations
3
checked on May 16, 2024
Page view(s)
36
checked on Sep 7, 2022
Download(s)
8
checked on Sep 7, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.