Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/35979
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dc.contributor.authorMUNUSWAMY, Revathy-
dc.contributor.authorDerave, Wim-
dc.contributor.authorDE BRANDT, Jana-
dc.contributor.authorBURTIN, Chris-
dc.contributor.authorAUMANN, Joseph-
dc.contributor.authorSPRUIT, Martijn A.-
dc.contributor.authorMICHIELS, Luc-
dc.date.accessioned2021-11-30T15:19:26Z-
dc.date.available2021-11-30T15:19:26Z-
dc.date.issued2021-
dc.date.submitted2021-10-28T11:32:46Z-
dc.identifier.citationJOURNAL OF INFLAMMATION RESEARCH, 14 , p. 4503 -4507-
dc.identifier.urihttp://hdl.handle.net/1942/35979-
dc.description.abstractChronic low-grade systemic inflammation is frequently observed in patients with chronic obstructive pulmonary disease (COPD), e.g., elevated pentameric CRP (pCRP). However, pCRP can dissociate to form monomeric CRP (mCRP) which exhibits a clear pro inflammatory behaviour in contrast to the more anti-inflammatory properties of pCRP. Therefore, mCRP may be an informative biomarker to demonstrate chronic low-grade systemic inflammation. This was confirmed by analysing serum samples from 38 patients with COPD and 18 non-COPD control persons (NCCP). mCRP was significantly elevated in patients with COPD vs. NCCP, indicating that mCRP might be considered as a new sensitive marker of chronic low-grade systemic inflammation.-
dc.description.sponsorshipDe Brandt J. is funded by the Flemish government. The Research of FWO Aspirant De Brandt J. is sponsored by FWO-grant #11B4718N. Burtin C. is funded by Limburgs Kankerfonds. The authors acknowledge Ms. Bogaers A. of Hasselt University (Diepenbeek, Belgium) for performing blood sampling and DXA scanning. The UBiLim (University Biobank Limburg; Belgium) is acknowledged as they provided storage and release of all human biological material used in this publication. (Linsen L. et al., Raising to the Challenge: Building a Federated Biobank to Accelerate Translational Research-The University Biobank Limburg. Front Med (Lausanne), 2019. 6: p. 224.)-
dc.language.isoen-
dc.publisherDOVE MEDICAL PRESS LTD-
dc.rights2021 Munuswamy et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/ terms.php and incorporate the Creative Commons Attribution –-
dc.subject.otherCOPD-
dc.subject.otherDlow-grade systemic inflammation-
dc.subject.otherpCRP-
dc.subject.othermCRP-
dc.titleMonomeric CRP is Elevated in Patients with COPD Compared to Non-COPD Control Persons-
dc.typeJournal Contribution-
dc.identifier.epage4507-
dc.identifier.spage4503-
dc.identifier.volume14-
local.format.pages5-
local.bibliographicCitation.jcatA1-
dc.description.notesMichiels, L (corresponding author), Hasselt Univ, Biomed Res Inst BIOMED, Fac Med & Life Sci, Hasselt, Belgium.-
dc.description.notesluc.michiels@uhasselt.be-
local.publisher.placePO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND-
local.type.refereedRefereed-
local.type.specifiedLetter-
dc.identifier.doi10.2147/JIR.S320659-
dc.identifier.pmid34522118-
dc.identifier.isiWOS:000703153600005-
dc.identifier.eissn1178-7031-
local.provider.typewosris-
local.uhasselt.uhpubyes-
local.description.affiliation[Munuswamy, Revathy; Michiels, Luc] Hasselt Univ, Biomed Res Inst BIOMED, Fac Med & Life Sci, Hasselt, Belgium.-
local.description.affiliation[De Brandt, Jana; Burtin, Chris] Hasselt Univ, Biomed Res Inst BIOMED, Fac Rehabil Sci, Rehabil Res Ctr REVAL, Hasselt, Belgium.-
local.description.affiliation[Derave, Wim] Univ Ghent, Dept Movement & Sports Sci, Ghent, Belgium.-
local.description.affiliation[Aumann, Joseph] Jessa Hosp, Dept Pneumol, Hasselt, Belgium.-
local.description.affiliation[Spruit, Martijn A.] CIRO, Dept Res & Dev, Horn, Netherlands.-
local.description.affiliation[Spruit, Martijn A.] Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Fac Hlth Med & Life Sci,Dept Resp Med, Maastricht, Netherlands.-
local.uhasselt.internationalyes-
item.fulltextWith Fulltext-
item.contributorMUNUSWAMY, Revathy-
item.contributorDerave, Wim-
item.contributorDE BRANDT, Jana-
item.contributorBURTIN, Chris-
item.contributorAUMANN, Joseph-
item.contributorSPRUIT, Martijn A.-
item.contributorMICHIELS, Luc-
item.fullcitationMUNUSWAMY, Revathy; Derave, Wim; DE BRANDT, Jana; BURTIN, Chris; AUMANN, Joseph; SPRUIT, Martijn A. & MICHIELS, Luc (2021) Monomeric CRP is Elevated in Patients with COPD Compared to Non-COPD Control Persons. In: JOURNAL OF INFLAMMATION RESEARCH, 14 , p. 4503 -4507.-
item.accessRightsOpen Access-
item.validationecoom 2022-
crisitem.journal.eissn1178-7031-
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