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Title: | A retrospective study on patients with chronic knee pain treated with ultrasound-guided radiofrequency of the genicular nerves (RECORGEN trial) | Authors: | BELBA, Amy Vanneste, Thibaut Van Kuijk, Sander M. J. MESOTTEN, Dieter Mestrum, Roel VAN BOXEM, Koen Van Lantschoot, Astrid BELLEMANS, Johan Van de Velde, Marc VAN ZUNDERT, Jan |
Issue Date: | 2022 | Publisher: | WILEY | Source: | Pain practice, 2021, 22 (3) , p. 340-348 | Abstract: | Introduction Radiofrequency (RF) treatment of the genicular nerves is a promising treatment for chronic osteoarthritic and persistent postsurgical knee pain (PPSP), refractory to conventional medical management. Methods The RECORGEN study is a retrospective single-center cohort study of patients treated with ultrasound-guided conventional RF of the genicular nerves for chronic knee pain in Hospital Oost-Limburg, Genk from September 2017 to June 2020. Subgroup analysis based on etiology of pain (PPSP and degenerative knee pain) was performed in addition to the total study population analysis. Outcome parameters were global perceived effect (GPE), Numeric Rating Scale for pain, consumption of strong opioids, and safety of the treatment at 6 weeks and cross-sectionally at a variable time point. Treatment success was defined as GPE >= 50%. Results Sixty-eight cases were screened of which 59 (46 diagnosed with PPSP and 13 with degenerative knee pain) were included in the study. Treatment success at 6 weeks was achieved in 19 of 59 interventions (32.2%) and was similar in both groups. Seventeen responders were evaluated at follow-up. 45.1% (8/17) continued to have a positive effect at the second time point. The mean duration of effect of the RF treatment was 8.3 months. Safety analysis at 6 weeks and at the second time point showed a good safety profile of the treatment. Conclusion Conventional RF of the genicular nerves was clinically successful in more than 30% of the study population refractory to conventional medical management. Overall, the treatment was well tolerated. The mean duration of effect was 8.3 months. | Notes: | Van Zundert, J (corresponding author), Maastricht Univ, Dept Anaesthesiol & Pain Med, Med Ctr, Postbus 5800, NL-6202 AZ Maastricht, Netherlands. jan.van.zundert@mumc.nl |
Keywords: | chronic knee pain;genicular nerves;osteoarthritis;persistent postsurgical pain;radiofrequency ablation | Document URI: | http://hdl.handle.net/1942/35993 | ISSN: | 1530-7085 | e-ISSN: | 1533-2500 | DOI: | 10.1111/papr.13088 | ISI #: | 000715934600001 | Rights: | 2021 The Authors. Pain Practice published by Wiley Periodicals LLC on behalf of World Institute of Pain.. This is an open access article under the terms of the Creative Commons Attribution NonCommercial License | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2022 |
Appears in Collections: | Research publications |
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Pain Practice - 2021 - Belba - A retrospective study on patients with chronic knee pain treated with ultrasoundāguided.pdf | Published version | 401.19 kB | Adobe PDF | View/Open |
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