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http://hdl.handle.net/1942/36039
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DC Field | Value | Language |
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dc.contributor.author | Cornelissen, Dennis | - |
dc.contributor.author | Boonen, Annelies | - |
dc.contributor.author | Evers, Silvia | - |
dc.contributor.author | VAN DEN BERGH, Joop | - |
dc.contributor.author | Bours, Sandrine | - |
dc.contributor.author | Wyers, Caroline E. | - |
dc.contributor.author | van Kuijk, Sander | - |
dc.contributor.author | van Oostwaard, Marsha | - |
dc.contributor.author | van der Weijden, Trudy | - |
dc.contributor.author | Hiligsmann, Mickael | - |
dc.date.accessioned | 2021-12-05T17:23:37Z | - |
dc.date.available | 2021-12-05T17:23:37Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-11-23T16:22:56Z | - |
dc.identifier.citation | BMC musculoskeletal disorders (Online), 22 (1) (Art N° 913) | - |
dc.identifier.uri | http://hdl.handle.net/1942/36039 | - |
dc.description.abstract | Background Given the health and economic burden of fractures related to osteoporosis, suboptimal adherence to medication and the increasing importance of shared-decision making, the Improvement of osteoporosis Care Organized by Nurses (ICON) study was designed to evaluate the effectiveness, cost-effectiveness and feasibility of a multi-component adherence intervention (MCAI) for patients with an indication for treatment with anti-osteoporosis medication, following assessment at the Fracture Liaison Service after a recent fracture. The MCAI involves two consultations at the FLS. During the first consultation, a decision aid is will be used to involve patients in the decision of whether to start anti-osteoporosis medication. During the follow-up visit, the nurse inquires about, and stimulates, medication adherence using motivational interviewing techniques. Methods A quasi-experimental trial to evaluate the (cost-) effectiveness and feasibility of an MCAI, consisting of a decision aid (DA) at the first visit, combined with nurse-led adherence support using motivational interviewing during the follow-up visit, in comparison with care as usual, in improving adherence to oral anti-osteoporosis medication for patients with a recent fracture two Dutch FLS. Medication persistence, defined as the proportion of patients who are persistent at one year assuming a refill gap < 30 days, is the primary outcome. Medication adherence, decision quality, subsequent fractures and mortality are the secondary outcomes. A lifetime cost-effectiveness analysis using a model-based economic evaluation and a process evaluation will also be conducted. A sample size of 248 patients is required to show an improvement in the primary outcome with 20%. Study follow-up is at 12 months, with measurements at baseline, after four months, and at 12 months. Discussion We expect that the ICON-study will show that the MCAI is a (cost-)effective intervention for improving persistence with anti-osteoporosis medication and that it is feasible for implementation at the FLS. | - |
dc.description.sponsorship | The ICON-study is funded by ZonMw research line Rational Pharmacotherapy, grant number 848016001. There are no other sponsors. The funding body played no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript. | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.rights | The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data | - |
dc.title | Improvement of osteoporosis Care Organized by Nurses: ICON study - Protocol of a quasi-experimental study to assess the (cost)-efectiveness of combining a decision aid with motivational interviewing for improving medication persistence in patients with a recent fracture being treated at the fracture liaison service | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 22 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Cornelissen, D (corresponding author), Maastricht Univ, Care & Publ Hlth Res Inst CAPHRI, Dept Hlth Serv Res, POB 616, NL-6200 MD Maastricht, Netherlands. | - |
dc.description.notes | d.cornelissen@maastrichtuniversity.nl | - |
local.publisher.place | CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 913 | - |
dc.identifier.doi | 10.1186/s12891-021-04743-2 | - |
dc.identifier.pmid | 34715838 | - |
dc.identifier.isi | WOS:000712823300002 | - |
dc.identifier.eissn | 1471-2474 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Cornelissen, Dennis; Evers, Silvia; Bours, Sandrine; Hiligsmann, Mickael] Maastricht Univ, Care & Publ Hlth Res Inst CAPHRI, Dept Hlth Serv Res, POB 616, NL-6200 MD Maastricht, Netherlands. | - |
local.description.affiliation | [Boonen, Annelies; Bours, Sandrine] Maastricht Univ, Med Ctr, Div Rheumatol, Dept Internal Med, Maastricht, Netherlands. | - |
local.description.affiliation | [Boonen, Annelies; Bours, Sandrine] Care & Publ Hlth Res Inst CAPHRI, Maastricht, Netherlands. | - |
local.description.affiliation | [Evers, Silvia] Netherlands Inst Mental Hlth & Addict, Trimbos Inst, Ctr Econ Evaluat & Machine Learning, Utrecht, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.; Wyers, Caroline E.; van Oostwaard, Marsha] VieCuri Med Ctr, Dept Internal Med, Venlo, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.; Wyers, Caroline E.; van Oostwaard, Marsha] Maastricht Univ, Med Ctr, Nutr & Translat Res Metab NUTRIM, Dept Internal Med, Maastricht, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.description.affiliation | [van Kuijk, Sander] Maastricht Univ, Med Ctr, Dept Clin Epidemiol & Med Technol Assessment KEMT, Maastricht, Netherlands. | - |
local.description.affiliation | [van der Weijden, Trudy] Maastricht Univ, Med Ctr, Care & Publ Hlth Res Inst CAPHRI, Dept Family Med, Maastricht, Netherlands. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Cornelissen, Dennis; Boonen, Annelies; Evers, Silvia; VAN DEN BERGH, Joop; Bours, Sandrine; Wyers, Caroline E.; van Kuijk, Sander; van Oostwaard, Marsha; van der Weijden, Trudy & Hiligsmann, Mickael (2021) Improvement of osteoporosis Care Organized by Nurses: ICON study - Protocol of a quasi-experimental study to assess the (cost)-efectiveness of combining a decision aid with motivational interviewing for improving medication persistence in patients with a recent fracture being treated at the fracture liaison service. In: BMC musculoskeletal disorders (Online), 22 (1) (Art N° 913). | - |
item.validation | ecoom 2022 | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
item.contributor | Cornelissen, Dennis | - |
item.contributor | Boonen, Annelies | - |
item.contributor | Evers, Silvia | - |
item.contributor | VAN DEN BERGH, Joop | - |
item.contributor | Bours, Sandrine | - |
item.contributor | Wyers, Caroline E. | - |
item.contributor | van Kuijk, Sander | - |
item.contributor | van Oostwaard, Marsha | - |
item.contributor | van der Weijden, Trudy | - |
item.contributor | Hiligsmann, Mickael | - |
crisitem.journal.issn | 1471-2474 | - |
crisitem.journal.eissn | 1471-2474 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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improvement.pdf | Published version | 2.05 MB | Adobe PDF | View/Open |
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