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http://hdl.handle.net/1942/36039
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DC Field | Value | Language |
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dc.contributor.author | Cornelissen, Dennis | - |
dc.contributor.author | Boonen, Annelies | - |
dc.contributor.author | Evers, Silvia | - |
dc.contributor.author | VAN DEN BERGH, Joop | - |
dc.contributor.author | Bours, Sandrine | - |
dc.contributor.author | Wyers, Caroline E. | - |
dc.contributor.author | van Kuijk, Sander | - |
dc.contributor.author | van Oostwaard, Marsha | - |
dc.contributor.author | van der Weijden, Trudy | - |
dc.contributor.author | Hiligsmann, Mickael | - |
dc.date.accessioned | 2021-12-05T17:23:37Z | - |
dc.date.available | 2021-12-05T17:23:37Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-11-23T16:22:56Z | - |
dc.identifier.citation | BMC MUSCULOSKELETAL DISORDERS, 22 (1) (Art N° 913) | - |
dc.identifier.uri | http://hdl.handle.net/1942/36039 | - |
dc.description.abstract | Background Given the health and economic burden of fractures related to osteoporosis, suboptimal adherence to medication and the increasing importance of shared-decision making, the Improvement of osteoporosis Care Organized by Nurses (ICON) study was designed to evaluate the effectiveness, cost-effectiveness and feasibility of a multi-component adherence intervention (MCAI) for patients with an indication for treatment with anti-osteoporosis medication, following assessment at the Fracture Liaison Service after a recent fracture. The MCAI involves two consultations at the FLS. During the first consultation, a decision aid is will be used to involve patients in the decision of whether to start anti-osteoporosis medication. During the follow-up visit, the nurse inquires about, and stimulates, medication adherence using motivational interviewing techniques. Methods A quasi-experimental trial to evaluate the (cost-) effectiveness and feasibility of an MCAI, consisting of a decision aid (DA) at the first visit, combined with nurse-led adherence support using motivational interviewing during the follow-up visit, in comparison with care as usual, in improving adherence to oral anti-osteoporosis medication for patients with a recent fracture two Dutch FLS. Medication persistence, defined as the proportion of patients who are persistent at one year assuming a refill gap < 30 days, is the primary outcome. Medication adherence, decision quality, subsequent fractures and mortality are the secondary outcomes. A lifetime cost-effectiveness analysis using a model-based economic evaluation and a process evaluation will also be conducted. A sample size of 248 patients is required to show an improvement in the primary outcome with 20%. Study follow-up is at 12 months, with measurements at baseline, after four months, and at 12 months. Discussion We expect that the ICON-study will show that the MCAI is a (cost-)effective intervention for improving persistence with anti-osteoporosis medication and that it is feasible for implementation at the FLS. | - |
dc.description.sponsorship | ZonMw research line Rational Pharmacotherapy [848016001] | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.subject.other | Cost-effectiveness; Process evaluation; Decision aid; Osteoporosis; | - |
dc.subject.other | Patient participation; Protocol; Medication adherence; Medication | - |
dc.subject.other | persistence; Fracture liaison service; Nurse | - |
dc.title | Improvement of osteoporosis Care Organized by Nurses: ICON study - Protocol of a quasi-experimental study to assess the (cost)-effectiveness of combining a decision aid with motivational interviewing for improving medication persistence in patients with a recent fracture being treated at the fracture liaison service | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 22 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Cornelissen, D (corresponding author), Maastricht Univ, Care & Publ Hlth Res Inst CAPHRI, Dept Hlth Serv Res, POB 616, NL-6200 MD Maastricht, Netherlands. | - |
dc.description.notes | d.cornelissen@maastrichtuniversity.nl | - |
local.publisher.place | CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 913 | - |
dc.identifier.doi | 10.1186/s12891-021-04743-2 | - |
dc.identifier.isi | WOS:000712823300002 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Cornelissen, Dennis; Evers, Silvia; Bours, Sandrine; Hiligsmann, Mickael] Maastricht Univ, Care & Publ Hlth Res Inst CAPHRI, Dept Hlth Serv Res, POB 616, NL-6200 MD Maastricht, Netherlands. | - |
local.description.affiliation | [Boonen, Annelies; Bours, Sandrine] Maastricht Univ, Med Ctr, Div Rheumatol, Dept Internal Med, Maastricht, Netherlands. | - |
local.description.affiliation | [Boonen, Annelies; Bours, Sandrine] Care & Publ Hlth Res Inst CAPHRI, Maastricht, Netherlands. | - |
local.description.affiliation | [Evers, Silvia] Netherlands Inst Mental Hlth & Addict, Trimbos Inst, Ctr Econ Evaluat & Machine Learning, Utrecht, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.; Wyers, Caroline E.; van Oostwaard, Marsha] VieCuri Med Ctr, Dept Internal Med, Venlo, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.; Wyers, Caroline E.; van Oostwaard, Marsha] Maastricht Univ, Med Ctr, Nutr & Translat Res Metab NUTRIM, Dept Internal Med, Maastricht, Netherlands. | - |
local.description.affiliation | [van den Bergh, Joop P.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.description.affiliation | [van Kuijk, Sander] Maastricht Univ, Med Ctr, Dept Clin Epidemiol & Med Technol Assessment KEMT, Maastricht, Netherlands. | - |
local.description.affiliation | [van der Weijden, Trudy] Maastricht Univ, Med Ctr, Care & Publ Hlth Res Inst CAPHRI, Dept Family Med, Maastricht, Netherlands. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.contributor | Cornelissen, Dennis | - |
item.contributor | Boonen, Annelies | - |
item.contributor | Evers, Silvia | - |
item.contributor | VAN DEN BERGH, Joop | - |
item.contributor | Bours, Sandrine | - |
item.contributor | Wyers, Caroline E. | - |
item.contributor | van Kuijk, Sander | - |
item.contributor | van Oostwaard, Marsha | - |
item.contributor | van der Weijden, Trudy | - |
item.contributor | Hiligsmann, Mickael | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2022 | - |
item.fullcitation | Cornelissen, Dennis; Boonen, Annelies; Evers, Silvia; VAN DEN BERGH, Joop; Bours, Sandrine; Wyers, Caroline E.; van Kuijk, Sander; van Oostwaard, Marsha; van der Weijden, Trudy & Hiligsmann, Mickael (2021) Improvement of osteoporosis Care Organized by Nurses: ICON study - Protocol of a quasi-experimental study to assess the (cost)-effectiveness of combining a decision aid with motivational interviewing for improving medication persistence in patients with a recent fracture being treated at the fracture liaison service. In: BMC MUSCULOSKELETAL DISORDERS, 22 (1) (Art N° 913). | - |
crisitem.journal.eissn | 1471-2474 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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improvement.pdf | Published version | 2.05 MB | Adobe PDF | View/Open |
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