Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/36806
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | DECKERS, Jana | - |
dc.contributor.author | HENDRIX, Sophie | - |
dc.contributor.author | Prinsen, Els | - |
dc.contributor.author | VANGRONSVELD, Jaco | - |
dc.contributor.author | CUYPERS, Ann | - |
dc.date.accessioned | 2022-03-07T14:26:43Z | - |
dc.date.available | 2022-03-07T14:26:43Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-03-04T13:56:52Z | - |
dc.identifier.citation | Antioxidants, 11 (1) (Art N° 6) | - |
dc.identifier.issn | - | |
dc.identifier.uri | http://hdl.handle.net/1942/36806 | - |
dc.description.abstract | Pollution by cadmium (Cd) is a worldwide problem, posing risks to human health and impacting crop yield and quality. Cadmium-induced phytotoxicity arises from an imbalance between antioxidants and pro-oxidants in favour of the latter. The Cd-induced depletion of the major antioxidant glutathione (GSH) strongly contributes to this imbalance. Rather than being merely an adverse effect of Cd exposure, the rapid depletion of root GSH levels was proposed to serve as an alert response. This alarm phase is crucial for an optimal stress response, which defines acclimation later on. To obtain a better understanding on the importance of GSH in the course of these responses and how these are defined by the rapid GSH depletion, analyses were performed in the GSH-deficient cadmium-sensitive 2-1 (cad2-1) mutant. Cadmium-induced root and leaf responses related to oxidative challenge, hydrogen peroxide (H2O2), GSH, ethylene, and 1-aminocyclopropane-1-carboxylic acid (ACC) were compared between wild-type (WT) and mutant Arabidopsis thaliana plants. Although the cad2-1 mutant has significantly lower GSH levels, root GSH depletion still occurred, suggesting that the chelating capacity of GSH is prioritised over its antioxidative function. We demonstrated that responses related to GSH metabolism and ACC production were accelerated in mutant roots and that stress persisted due to suboptimal acclimation. In general, the redox imbalance in cad2-1 mutant plants and the lack of proper transient ethylene signalling contributed to this suboptimal acclimation, resulting in a more pronounced Cd effect. | - |
dc.description.sponsorship | This research was funded by Research Foundation-Flanders (FWO) through a PhD grant fellowship for Jana Deckers (1182220N). Additional funding came from the FWO project to Ann Cuypers (G0C7518N). We thank Sevgi Oden, Ann Wijgaerts, Hans Vanbuel, and Carine Put for their expertise, assistance, and technical support. | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.rights | 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | Arabidopsis thaliana | - |
dc.subject.other | 1-aminocyclopropane-1-carboxylic acid | - |
dc.subject.other | cadmium | - |
dc.subject.other | cadmium-sensitive 2-1 mutant | - |
dc.subject.other | ethylene | - |
dc.subject.other | glutathione | - |
dc.subject.other | hydrogen peroxide | - |
dc.subject.other | oxidative challenge | - |
dc.title | Glutathione Is Required for the Early Alert Response and Subsequent Acclimation in Cadmium-Exposed Arabidopsis thaliana Plants | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 11 | - |
local.format.pages | 21 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Cuypers, A (corresponding author), Hasselt Univ, Ctr Environm Sci, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium. | - |
dc.description.notes | jana.deckers@uhasselt.be; sophie.hendrix@uhasselt.be; | - |
dc.description.notes | els.prinsen@uantwerpen.be; jaco.vangronsveld@uhasselt.be; | - |
dc.description.notes | ann.cuypers@uhasselt.be | - |
local.publisher.place | ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 6 | - |
dc.identifier.doi | 10.3390/antiox11010006 | - |
dc.identifier.pmid | 35052510 | - |
dc.identifier.isi | WOS:000757434400001 | - |
dc.contributor.orcid | Cuypers, Ann/0000-0002-0171-0245; Hendrix, Sophie/0000-0001-7436-0234; | - |
dc.contributor.orcid | Prinsen, Els/0000-0003-4320-1585 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Deckers, Jana; Hendrix, Sophie; Vangronsveld, Jaco; Cuypers, Ann] Hasselt Univ, Ctr Environm Sci, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium. | - |
local.description.affiliation | [Hendrix, Sophie] Univ Bonn, Inst Crop Sci & Resource Conservat INRES, D-53113 Bonn, Germany. | - |
local.description.affiliation | [Prinsen, Els] Univ Antwerp, Dept Biol, Groenenborgerlaan 171, B-2020 Antwerp, Belgium. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.fullcitation | DECKERS, Jana; HENDRIX, Sophie; Prinsen, Els; VANGRONSVELD, Jaco & CUYPERS, Ann (2022) Glutathione Is Required for the Early Alert Response and Subsequent Acclimation in Cadmium-Exposed Arabidopsis thaliana Plants. In: Antioxidants, 11 (1) (Art N° 6). | - |
item.contributor | DECKERS, Jana | - |
item.contributor | HENDRIX, Sophie | - |
item.contributor | Prinsen, Els | - |
item.contributor | VANGRONSVELD, Jaco | - |
item.contributor | CUYPERS, Ann | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2023 | - |
crisitem.journal.eissn | 2076-3921 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Glutathione Is Required for the Early Alert Response and Subsequent Acclimation in Cadmium-Exposed Arabidopsis thaliana Plants.pdf | Published version | 2.09 MB | Adobe PDF | View/Open |
WEB OF SCIENCETM
Citations
5
checked on May 8, 2024
Page view(s)
40
checked on Aug 9, 2022
Download(s)
14
checked on Aug 9, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.