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http://hdl.handle.net/1942/37125
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DC Field | Value | Language |
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dc.contributor.author | KEMPS, Hannelore | - |
dc.contributor.author | GERVOIS, Pascal | - |
dc.contributor.author | BRONE, Bert | - |
dc.contributor.author | Lemmens, Robin | - |
dc.contributor.author | BRONCKAERS, Annelies | - |
dc.date.accessioned | 2022-03-31T09:51:07Z | - |
dc.date.available | 2022-03-31T09:51:07Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-03-31T09:40:59Z | - |
dc.identifier.citation | PHARMACOLOGY & THERAPEUTICS, 235 (Art N° 108160) | - |
dc.identifier.issn | 0163-7258 | - |
dc.identifier.uri | http://hdl.handle.net/1942/37125 | - |
dc.description.abstract | Editor name: S.J. Enna Although spontaneous recovery can occur following ischemic stroke due to endogenous neuronal reorganization and neuroplastic events, the degree of functional improvement is highly variable, causing many patients to remain permanently impaired. In the last decades, non-invasive brain stimulation (NIBS) techniques have emerged as potential add-on interventions to the standard neurorehabilitation programs to improve post-stroke recovery. Due to their ability to modulate cortical excitability and to induce neuroreparative processes in the brain, multiple studies have assessed the safety, efficacy and (sub)cellular mechanisms of NIBS following ischemic stroke. In this review, an overview will be provided of the different NIBS techniques that are currently being investigated in (pre)clinical stroke studies. The NIBS therapies that will be discussed include transcranial magnetic stimulation, transcranial direct current stimulation and extremely low frequency electromagnetic stimulation. First, an overview will be given of the cellular mechanisms induced by NIBS that are associated with enhanced stroke outcome in preclinical models. Furthermore, the current knowledge on safety and efficacy of these NIBS techniques in stroke patients will be reviewed. | - |
dc.description.sponsorship | This research is supported by the ‘Special Research Funds’ (BOF) of Hasselt University (grants # BOF20TT04 and 18NI06BOF to Annelies Bronckaers and Hannelore Kemps). Robin Lemmens is a senior clinical investigator of Fonds Wetenschappelijk Onderzoek (FWO) Flanders. | - |
dc.language.iso | en | - |
dc.publisher | - | |
dc.rights | 2022 Published by Elsevier Inc | - |
dc.subject.other | Ischemic stroke | - |
dc.subject.other | Transcranial magnetic stimulation | - |
dc.subject.other | Transcranial direct current stimulation | - |
dc.subject.other | Extremely low frequency electromagnetic stimulation | - |
dc.subject.other | (Sub)cellular mechanisms | - |
dc.subject.other | Clinical trials | - |
dc.title | Non-invasive brain stimulation as therapeutic approach for ischemic stroke: Insights into the (sub)cellular mechanisms | - |
dc.type | Journal Contribution | - |
dc.identifier.spage | 108160 | - |
dc.identifier.volume | 235 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
local.bibliographicCitation.artnr | 108160 | - |
dc.identifier.doi | 10.1016/j.pharmthera.2022.108160 | - |
dc.identifier.isi | 000787883300003 | - |
dc.identifier.eissn | 1879-016X | - |
local.provider.type | - | |
local.uhasselt.international | no | - |
item.validation | ecoom 2023 | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.fullcitation | KEMPS, Hannelore; GERVOIS, Pascal; BRONE, Bert; Lemmens, Robin & BRONCKAERS, Annelies (2022) Non-invasive brain stimulation as therapeutic approach for ischemic stroke: Insights into the (sub)cellular mechanisms. In: PHARMACOLOGY & THERAPEUTICS, 235 (Art N° 108160). | - |
item.contributor | KEMPS, Hannelore | - |
item.contributor | GERVOIS, Pascal | - |
item.contributor | BRONE, Bert | - |
item.contributor | Lemmens, Robin | - |
item.contributor | BRONCKAERS, Annelies | - |
crisitem.journal.issn | 0163-7258 | - |
crisitem.journal.eissn | 1879-016X | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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1-s2.0-S0163725822000547-main.pdf Restricted Access | Published version | 1.3 MB | Adobe PDF | View/Open Request a copy |
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